JP6008846B2 - 修飾されたＲＮａｓｅＨ及び核酸増幅の検出 - Google Patents
修飾されたＲＮａｓｅＨ及び核酸増幅の検出 Download PDFInfo
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
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- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
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| PCT/KR2011/003811 WO2011149255A2 (en) | 2010-05-25 | 2011-05-25 | Modified rnase h and detection of nucleic acid amplification |
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| US8911948B2 (en) * | 2008-04-30 | 2014-12-16 | Integrated Dna Technologies, Inc. | RNase H-based assays utilizing modified RNA monomers |
| US20140255925A9 (en) * | 2008-04-30 | 2014-09-11 | Integrated Dna Technologies | Modified rnase h enzymes and their uses |
| AU2009242546B2 (en) | 2008-04-30 | 2015-01-22 | Integrated Dna Technologies, Inc. | RNase-H-based assays utilizing modified RNA monomers |
| US9506057B2 (en) | 2010-03-26 | 2016-11-29 | Integrated Dna Technologies, Inc. | Modifications for antisense compounds |
| AU2011299233B2 (en) | 2010-09-07 | 2016-09-15 | Integrated Dna Technologies, Inc. | Modifications for antisense compounds |
| WO2012135053A2 (en) | 2011-03-25 | 2012-10-04 | Integrated Dna Technologies, Inc. | Rnase h-based assays utilizing modified rna monomers |
| KR101753833B1 (ko) * | 2012-01-09 | 2017-07-05 | 사회복지법인 삼성생명공익재단 | 절단 가능한 프로브를 이용한 만성골수성백혈병 유전자의 멀티플렉스 검출 방법 |
| US20130231261A1 (en) * | 2012-02-17 | 2013-09-05 | Institute For Systems Biology | Rnase h-based rna profiling |
| EP2828403A1 (de) * | 2012-03-19 | 2015-01-28 | Integrated DNA Technologies Inc. | Modifizierte rnase-h-enzyme und verwendungen davon |
| EP3044326B1 (de) * | 2013-09-13 | 2017-12-06 | F. Hoffmann-La Roche AG | Verwendung von oligo-dt-molekülen zur verhinderung der erzeugung von hochmolekularen pcr-produkten durch polya-träger |
| CN105579589A (zh) * | 2013-09-30 | 2016-05-11 | 日本电气方案创新株式会社 | 用于分析靶标的方法和试剂盒 |
| CN103966184A (zh) * | 2014-05-06 | 2014-08-06 | 江西省科学院微生物研究所 | 一种实时热启动Taq酶及其制备方法 |
| WO2016028671A1 (en) * | 2014-08-19 | 2016-02-25 | Bio-Rad Laboratories, Inc. | Rna amplification methods |
| WO2016065192A1 (en) | 2014-10-22 | 2016-04-28 | Roka Bioscience, Inc. | Compositions and methods for the detection of nucleic acids |
| EP3287530A4 (de) * | 2015-04-20 | 2018-11-21 | KIM, Sung-Chun | Verfahren zur analyse von biomolekülen mittels verwendung eines externen als biomoleküls als standardmaterial und kit dafür |
| KR101901749B1 (ko) | 2016-02-15 | 2018-09-28 | 주식회사 누리바이오 | 실시간 핵산 또는 단백질 검출용 단일핵산 및 이를 이용한 검출 방법 |
| WO2017142297A1 (ko) * | 2016-02-15 | 2017-08-24 | 주식회사 누리바이오 | 실시간 핵산 또는 단백질 검출용 단일핵산 및 이를 이용한 검출 방법 |
| US11046940B2 (en) | 2016-04-12 | 2021-06-29 | Solis Biodyne Ou | Synthetic reverse transcriptases and uses thereof |
| US20190127783A1 (en) * | 2016-04-27 | 2019-05-02 | Prominex, Inc. | Compositions and methods for the detection of nucleic acids |
| WO2017214561A1 (en) * | 2016-06-10 | 2017-12-14 | Life Technologies Corporation | Methods and compositions for nucleic acid amplification |
| JP2019536435A (ja) * | 2016-09-27 | 2019-12-19 | ヌリバイオ カンパニー リミテッドＮｕｒｉｂｉｏ Ｃｏ．， Ｌｔｄ． | スモールｒｎａ又はスモールｒｎａに関連するタンパク質を検出する方法 |
| US11667952B2 (en) | 2017-08-24 | 2023-06-06 | Takara Bio Usa, Inc. | Methods of producing nucleic acids using oligonucleotides modified by a stimulus |
| JP2019198259A (ja) * | 2018-05-15 | 2019-11-21 | 株式会社島津製作所 | １ステップｒｔ−ｐｃｒ法 |
| KR102516307B1 (ko) * | 2019-09-23 | 2023-04-03 | 주식회사 원드롭 | RNase H 효소 및 이의 항체를 포함하는, 표적 핵산 증폭용 조성물 및 이의 용도 |
| US20240011084A1 (en) * | 2020-11-03 | 2024-01-11 | Northwestern University | METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAs CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE |
| WO2023246733A1 (en) * | 2022-06-21 | 2023-12-28 | Genevide Biotech Co., Ltd. | Methods and systems for nucleic acid detection |
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2011
- 2011-05-16 US US13/108,311 patent/US8618253B2/en active Active
- 2011-05-25 EP EP11786887.7A patent/EP2576774B1/de active Active
- 2011-05-25 CN CN201710160001.6A patent/CN106947749A/zh not_active Withdrawn
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| Publication number | Publication date |
|---|---|
| US20140087968A1 (en) | 2014-03-27 |
| US9598729B2 (en) | 2017-03-21 |
| JP2016146846A (ja) | 2016-08-18 |
| KR101865870B1 (ko) | 2018-06-11 |
| CN102918147B (zh) | 2017-04-12 |
| US20110294674A1 (en) | 2011-12-01 |
| US8618253B2 (en) | 2013-12-31 |
| EP2576774A2 (de) | 2013-04-10 |
| JP2013528384A (ja) | 2013-07-11 |
| WO2011149255A3 (en) | 2012-05-18 |
| WO2011149255A9 (en) | 2012-08-16 |
| CN102918147A (zh) | 2013-02-06 |
| WO2011149255A2 (en) | 2011-12-01 |
| EP2576774B1 (de) | 2016-01-06 |
| CN106947749A (zh) | 2017-07-14 |
| EP2576774A4 (de) | 2013-12-11 |
| KR20130021351A (ko) | 2013-03-05 |
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