JP5987249B2 - 溶液中でミクロンサイズの物体を検出するための光学的検出方法 - Google Patents

溶液中でミクロンサイズの物体を検出するための光学的検出方法 Download PDF

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JP5987249B2
JP5987249B2 JP2012533626A JP2012533626A JP5987249B2 JP 5987249 B2 JP5987249 B2 JP 5987249B2 JP 2012533626 A JP2012533626 A JP 2012533626A JP 2012533626 A JP2012533626 A JP 2012533626A JP 5987249 B2 JP5987249 B2 JP 5987249B2
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detection method
optical detection
droplet
droplets
particles
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JP2013507630A (ja
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アリエ、セドリック
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コミシリア ア レネルジ アトミック エ オ エナジーズ オルタネティヴズ
コミシリア ア レネルジ アトミック エ オ エナジーズ オルタネティヴズ
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4022—Concentrating samples by thermal techniques; Phase changes
    • G01N2001/4027—Concentrating samples by thermal techniques; Phase changes evaporation leaving a concentrated sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1481—Optical analysis of particles within droplets

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  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
JP2012533626A 2009-10-16 2010-10-14 溶液中でミクロンサイズの物体を検出するための光学的検出方法 Active JP5987249B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0904966 2009-10-16
FR0904966A FR2951542B1 (fr) 2009-10-16 2009-10-16 Procede de detection optique d'objets micrometriques en solution
PCT/EP2010/065382 WO2011045360A1 (fr) 2009-10-16 2010-10-14 Procédé de détection optique d'objets micrométriques en solution

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JP2013507630A JP2013507630A (ja) 2013-03-04
JP5987249B2 true JP5987249B2 (ja) 2016-09-07

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JP2012533626A Active JP5987249B2 (ja) 2009-10-16 2010-10-14 溶液中でミクロンサイズの物体を検出するための光学的検出方法
JP2015222347A Pending JP2016057307A (ja) 2009-10-16 2015-11-12 溶液中でミクロンサイズの物体を検出するための光学的検出方法

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US (1) US8605265B2 (https=)
EP (1) EP2488847B1 (https=)
JP (2) JP5987249B2 (https=)
CN (1) CN102575977A (https=)
FR (1) FR2951542B1 (https=)
IN (1) IN2012DN03099A (https=)
WO (1) WO2011045360A1 (https=)

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CN102713720B (zh) 2009-10-28 2016-05-11 阿兰蒂克微科学股份有限公司 显微成像装置和显微成像方法
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
US8767069B2 (en) * 2010-06-30 2014-07-01 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
FR2991457B1 (fr) * 2012-06-01 2014-07-18 Commissariat Energie Atomique Procede et systeme de caracterisation de la vitesse de deplacement de particules contenues dans un liquide, telles que des particules sanguines
FR2993276B1 (fr) 2012-07-12 2015-07-24 Commissariat Energie Atomique Composition pour la detection optique de particules, comprenant de l'eau, les particules, un surfactant et un polymere hydrophile, systeme et procede de detection optique associes
FR2993372B1 (fr) * 2012-07-13 2015-04-10 Commissariat Energie Atomique Procede et systeme de reconstruction de proprietes optiques d'objets diffractants baignant dans un milieu liquide
FR2998493B1 (fr) * 2012-11-27 2015-02-13 Commissariat Energie Atomique Procede de formation d'un film liquide sur un support
CA2938896A1 (en) * 2013-02-06 2014-08-14 Alentic Microscience Inc. Detecting and using light representative of a sample
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
FR3002634B1 (fr) * 2013-02-28 2015-04-10 Commissariat Energie Atomique Procede d'observation d'au moins un objet, tel qu'une entite biologique, et systeme d'imagerie associe
SG10201707599WA (en) * 2013-03-15 2017-10-30 Richard Harry Turner A System And Methods For The In Vitro Detection Of Particles And Soluble Chemical Entities In Body Fluids
JP2016531282A (ja) 2013-06-26 2016-10-06 アレンティック マイクロサイエンス インコーポレイテッド 顕微鏡法に関するサンプル処理の改善
FR3041474A1 (fr) 2015-09-23 2017-03-24 Commissariat Energie Atomique Dispositif d’imagerie sans lentille et procede d’observation associe
FR3062209B1 (fr) * 2017-01-25 2021-08-27 Commissariat Energie Atomique Detecteur optique de particules
CN108844936A (zh) * 2018-07-09 2018-11-20 领航基因科技（杭州）有限公司 一种三维液滴检测系统及检测方法
EP3969604B1 (en) 2019-05-13 2026-03-18 Vrije Universiteit Brussel Methods and systems for particle characterisation

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JP2890730B2 (ja) * 1990-07-27 1999-05-17 ジェイエスアール株式会社 検定液中の微粒子数の測定方法
JPH04316478A (ja) * 1991-04-12 1992-11-06 Nec Corp 生物試料観察装置、システムおよび方法
JPH06311879A (ja) * 1993-03-15 1994-11-08 Nec Corp バイオセンサ
JPH0755664A (ja) * 1993-08-13 1995-03-03 Nikon Corp 細胞及び染色体の標本用基材
CA2276462C (en) * 1996-12-31 2007-06-12 High Throughput Genomics, Inc. Multiplexed molecular analysis system apparatus and method
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Publication number Publication date
JP2016057307A (ja) 2016-04-21
US20110228256A1 (en) 2011-09-22
US8605265B2 (en) 2013-12-10
CN102575977A (zh) 2012-07-11
JP2013507630A (ja) 2013-03-04
WO2011045360A1 (fr) 2011-04-21
FR2951542A1 (fr) 2011-04-22
FR2951542B1 (fr) 2011-12-02
IN2012DN03099A (https=) 2015-09-18
EP2488847A1 (fr) 2012-08-22
EP2488847B1 (fr) 2017-11-15

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