IN2012DN03099A - - Google Patents

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Publication number
IN2012DN03099A
IN2012DN03099A IN3099DEN2012A IN2012DN03099A IN 2012DN03099 A IN2012DN03099 A IN 2012DN03099A IN 3099DEN2012 A IN3099DEN2012 A IN 3099DEN2012A IN 2012DN03099 A IN2012DN03099 A IN 2012DN03099A
Authority
IN
India
Prior art keywords
organisms
carried out
liquid droplet
particles
detection
Prior art date
Application number
Inventor
Allier Cedric
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Publication of IN2012DN03099A publication Critical patent/IN2012DN03099A/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4022—Concentrating samples by thermal techniques; Phase changes
    • G01N2001/4027—Concentrating samples by thermal techniques; Phase changes evaporation leaving a concentrated sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1481—Optical analysis of particles within droplets

Landscapes

  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

The general field of the invention is that of contact imaging devices. The process relates to detecting micron- or submicron-sized particles or organisms by means of such a device, said particles or organisms being immersed in a liquid droplet (G) and the detection being carried out by means of a matrix of photosensitive cells or photosites. The process comprises one detection step or a succession of detection steps carried out while the liquid droplet is evaporating. It may also comprise a detection step carried out after the liquid droplet has evaporated. Under certain conditions, the process allows a three-dimensional distribution of the particles or organisms in the initial unevaporated droplet to be reconstructed.
IN3099DEN2012 2009-10-16 2010-10-14 IN2012DN03099A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0904966A FR2951542B1 (en) 2009-10-16 2009-10-16 METHOD FOR OPTICALLY DETECTING MICROMETRIC OBJECTS IN SOLUTION
PCT/EP2010/065382 WO2011045360A1 (en) 2009-10-16 2010-10-14 Method for optically detecting dissolved micrometric objects

Publications (1)

Publication Number Publication Date
IN2012DN03099A true IN2012DN03099A (en) 2015-09-18

Family

ID=42153733

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3099DEN2012 IN2012DN03099A (en) 2009-10-16 2010-10-14

Country Status (7)

Country Link
US (1) US8605265B2 (en)
EP (1) EP2488847B1 (en)
JP (2) JP5987249B2 (en)
CN (1) CN102575977A (en)
FR (1) FR2951542B1 (en)
IN (1) IN2012DN03099A (en)
WO (1) WO2011045360A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9075225B2 (en) 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
CN105974571B (en) 2009-10-28 2019-05-28 阿兰蒂克微科学股份有限公司 Micro-imaging
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
US8767069B2 (en) * 2010-06-30 2014-07-01 Luminex Corporation Apparatus, system, and method for increasing measurement accuracy in a particle imaging device using light distribution
FR2991457B1 (en) * 2012-06-01 2014-07-18 Commissariat Energie Atomique METHOD AND SYSTEM FOR CHARACTERIZING THE SPEED OF DISPLACEMENT OF PARTICLES CONTAINED IN A LIQUID, SUCH AS BLOOD PARTICULATES
FR2993276B1 (en) * 2012-07-12 2015-07-24 Commissariat Energie Atomique COMPOSITION FOR OPTICALLY DETECTING PARTICLES, COMPRISING WATER, PARTICLES, SURFACTANT AND HYDROPHILIC POLYMER, SYSTEM AND METHOD FOR OPTICAL DETECTION THEREOF
FR2993372B1 (en) * 2012-07-13 2015-04-10 Commissariat Energie Atomique METHOD AND SYSTEM FOR RECONSTRUCTING OPTICAL PROPERTIES OF DIFFRACTING OBJECTS BATHING IN A LIQUID ENVIRONMENT
FR2998493B1 (en) * 2012-11-27 2015-02-13 Commissariat Energie Atomique METHOD FOR FORMING A LIQUID FILM ON A SUPPORT
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
CA2938896A1 (en) * 2013-02-06 2014-08-14 Alentic Microscience Inc. Detecting and using light representative of a sample
FR3002634B1 (en) * 2013-02-28 2015-04-10 Commissariat Energie Atomique METHOD OF OBSERVING AT LEAST ONE OBJECT, SUCH AS A BIOLOGICAL ENTITY, AND ASSOCIATED IMAGING SYSTEM
JP2016522880A (en) * 2013-03-15 2016-08-04 リチャード・ハリー・ターナー System and method for in vitro detection of particles and soluble chemicals in body fluids
CA2953620C (en) 2013-06-26 2020-08-25 Alentic Microscience Inc. Sample processing improvements for microscopy
FR3041474A1 (en) 2015-09-23 2017-03-24 Commissariat Energie Atomique IMAGING DEVICE WITHOUT LENS AND ASSOCIATED OBSERVATION METHOD
FR3062209B1 (en) * 2017-01-25 2021-08-27 Commissariat Energie Atomique OPTICAL PARTICLE DETECTOR
CN108844936A (en) * 2018-07-09 2018-11-20 领航基因科技（杭州）有限公司 A kind of three-dimensional drop detection system and detection method
CN113939730A (en) * 2019-05-13 2022-01-14 荷语布鲁塞尔自由大学 Method and system for particle characterization

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FR2192708A5 (en) * 1972-07-13 1974-02-08 Ctre Nal Transf Sion San
JP2890730B2 (en) * 1990-07-27 1999-05-17 ジェイエスアール株式会社 Method for measuring the number of fine particles in the test solution
JPH04316478A (en) * 1991-04-12 1992-11-06 Nec Corp Device for observing test specimen of organism, system and method
JPH06311879A (en) * 1993-03-15 1994-11-08 Nec Corp Biosensor
JPH0755664A (en) * 1993-08-13 1995-03-03 Nikon Corp Substrates for cell and chromosome specimens
CA2389358C (en) * 1996-12-31 2008-07-15 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
JP3979718B2 (en) * 1998-03-23 2007-09-19 大日本印刷株式会社 Droplet fixing device for measuring chip and measuring chip preparation device having the fixing device
WO2002078906A2 (en) * 2001-03-29 2002-10-10 Cellect Technologies Corp. Methods devices and systems for sorting and separating particles
CN100436574C (en) * 2001-09-06 2008-11-26 基因描绘系统有限公司 Rapid detection of replicating cells
JP4030438B2 (en) * 2003-01-29 2008-01-09 株式会社トクヤマ Immunological measurement method and immunochromatography method measurement kit.
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US7201878B2 (en) * 2004-03-26 2007-04-10 The United States Of America As Represented By The Secretary Of The Army Aerosol particle analyzer for measuring an analyte in airborne particles
US7751048B2 (en) * 2004-06-04 2010-07-06 California Institute Of Technology Optofluidic microscope device
FR2887983A1 (en) * 2005-06-30 2007-01-05 Commissariat Energie Atomique Microfluid preparation device comprising a distributor to distribute liquid in droplets to first concentration, a droplet displacer with electro wetting comprising a substrate with hydrophobic surface, and a droplet evaporator
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US20120224053A1 (en) * 2009-06-17 2012-09-06 Board Of Regents, The University Of Texas System Method and apparatus for quantitative microimaging

Also Published As

Publication number Publication date
JP2016057307A (en) 2016-04-21
CN102575977A (en) 2012-07-11
EP2488847A1 (en) 2012-08-22
JP5987249B2 (en) 2016-09-07
US8605265B2 (en) 2013-12-10
FR2951542B1 (en) 2011-12-02
FR2951542A1 (en) 2011-04-22
WO2011045360A1 (en) 2011-04-21
JP2013507630A (en) 2013-03-04
US20110228256A1 (en) 2011-09-22
EP2488847B1 (en) 2017-11-15

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