JP5941072B2 - マイクロニードルデバイス及び方法 - Google Patents

マイクロニードルデバイス及び方法 Download PDF

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Publication number
JP5941072B2
JP5941072B2 JP2013557802A JP2013557802A JP5941072B2 JP 5941072 B2 JP5941072 B2 JP 5941072B2 JP 2013557802 A JP2013557802 A JP 2013557802A JP 2013557802 A JP2013557802 A JP 2013557802A JP 5941072 B2 JP5941072 B2 JP 5941072B2
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Japan
Prior art keywords
microneedle
local anesthetic
microneedles
coating
array
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JP2013557802A
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English (en)
Japanese (ja)
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JP2014514022A (ja
JP2014514022A5 (enExample
Inventor
イン チャン
イン チャン
ジェイ．ハンセン クリステン
ジェイ．ハンセン クリステン
エス．ディターマン アミー
エス．ディターマン アミー
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3M Innovative Properties Co
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3M Innovative Properties Co
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Publication of JP2014514022A5 publication Critical patent/JP2014514022A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

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  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
JP2013557802A 2011-03-07 2012-03-06 マイクロニードルデバイス及び方法 Active JP5941072B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161449988P 2011-03-07 2011-03-07
US61/449,988 2011-03-07
PCT/US2012/027858 WO2012122163A1 (en) 2011-03-07 2012-03-06 Microneedle devices and methods

Publications (3)

Publication Number Publication Date
JP2014514022A JP2014514022A (ja) 2014-06-19
JP2014514022A5 JP2014514022A5 (enExample) 2015-04-23
JP5941072B2 true JP5941072B2 (ja) 2016-06-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013557802A Active JP5941072B2 (ja) 2011-03-07 2012-03-06 マイクロニードルデバイス及び方法

Country Status (11)

Country Link
US (2) US20140066843A1 (enExample)
EP (1) EP2683359B1 (enExample)
JP (1) JP5941072B2 (enExample)
KR (1) KR102058978B1 (enExample)
CN (1) CN103429222B (enExample)
AU (1) AU2012225609B2 (enExample)
BR (1) BR112013022955A2 (enExample)
CA (1) CA2829354C (enExample)
DK (1) DK2683359T3 (enExample)
ES (1) ES2542012T3 (enExample)
WO (1) WO2012122163A1 (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US9687641B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
EP2765927B1 (en) 2011-10-12 2021-02-24 Vaxxas Pty Limited Delivery device
HK1209658A1 (en) * 2012-05-01 2016-04-08 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
CA2889500A1 (en) * 2012-11-02 2014-05-08 Cosmed Pharmaceutical Co., Ltd. Retinoic acid microneedle
JP6865524B2 (ja) 2012-12-21 2021-04-28 コリウム， インコーポレイテッド 治療剤を送達するためのマイクロアレイおよび使用方法
JP6487899B2 (ja) 2013-03-12 2019-03-20 コリウム インターナショナル， インコーポレイテッド 微小突起アプリケータ
WO2014144973A1 (en) 2013-03-15 2014-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP4059450A1 (en) * 2013-03-15 2022-09-21 Corium, Inc. Microstructure array for delivery of active agents
EP2968118B1 (en) 2013-03-15 2022-02-09 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US10195410B2 (en) * 2013-07-22 2019-02-05 Tuo Jin Fabrication process of phase-transition microneedle patch
RU2719927C2 (ru) * 2013-09-30 2020-04-23 Джорджия Тек Рисёч Корпорейшн Микроигольчатые пластыри, системы и способы
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
KR101703050B1 (ko) * 2014-07-10 2017-02-07 주식회사 주빅 경피전달용 미세돌기 구조체
WO2016033540A1 (en) * 2014-08-29 2016-03-03 Corium International, Inc. Microstructure array for delivery of active agents
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
KR102169536B1 (ko) 2014-09-11 2020-10-23 히사미쓰 세이야꾸 가부시키가이샤 마이크로니들 디바이스
SG11201702779PA (en) 2014-10-27 2017-05-30 Hisamitsu Pharmaceutical Co Microneedle device containing recombinant follicle stimulating hormone
WO2016084701A1 (ja) * 2014-11-28 2016-06-02 テルモ株式会社 マイクロニードルデバイス
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
BR112017028392B1 (pt) 2015-06-30 2022-06-21 The Gillette Company Llc Método para fabricação de estrutura de gume cortante, lâmina e caixa de lâminas
AU2016333148B2 (en) 2015-09-28 2021-10-14 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
KR101876176B1 (ko) * 2016-02-17 2018-07-09 가톨릭관동대학교산학협력단 봉독 추출물 함유 경피투과 패치
KR101876177B1 (ko) * 2016-02-17 2018-07-09 가톨릭관동대학교산학협력단 경피투과 보툴리눔 독소 패치
KR102139337B1 (ko) * 2016-03-17 2020-07-29 주식회사 엘지생활건강 미세바늘패치를 이용한 히알루론산 필러
US10562200B2 (en) 2016-06-28 2020-02-18 The Gillette Company Llc Polymeric cutting edge structures and method of manufacturing polymeric cutting edge structures
KR101779393B1 (ko) * 2016-07-22 2017-09-19 주식회사 파마리서치프로덕트 핵산을 포함하는 마이크로니들 어레이 및 이의 제조방법
AU2018222745B2 (en) 2017-02-17 2021-02-18 Allergan, Inc. Microneedle array with active ingredient
CN115923337A (zh) 2017-03-31 2023-04-07 瓦克萨斯私人有限公司 用于涂覆表面的设备和方法
TWI633901B (zh) * 2017-05-16 2018-09-01 怡定興科技股份有限公司 醫美微針貼片之製作方法
JP2018196401A (ja) * 2017-05-19 2018-12-13 ロレアル マイクロニードルシート
DE102017117784A1 (de) * 2017-08-04 2019-02-07 Lts Lohmann Therapie-Systeme Ag Applikatorsystem enthaltend ein Mikronadelarray aufweisend einen Wirkstoff für die Wundheilung
KR102006071B1 (ko) 2017-08-18 2019-07-31 가천대학교 산학협력단 마이크로 니들 및 이의 제조방법
US11596592B2 (en) 2017-09-19 2023-03-07 Lg Household & Health Care Ltd. Hyaluronic acid filler using microneedle patch
JP2021506790A (ja) * 2017-12-14 2021-02-22 エルテーエス ローマン テラピー−ジステーメ アーゲー 塩形態の有効成分を含むマイクロニードルアレイ
WO2019226599A1 (en) * 2018-05-22 2019-11-28 Alkalidx, Inc. Diagnostics and treatments of anesthetic insensitive subjects
US11460411B2 (en) * 2018-06-18 2022-10-04 Kindeva Drug Delivery L.P. Process and apparatus for inspecting microneedle arrays
AU2020255670B2 (en) * 2019-03-29 2025-12-11 Vaxxas Pty Ltd Vaccination using high-density microprojection array patch
WO2020232394A1 (en) 2019-05-16 2020-11-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Microneedle arrays with undercut features for cutaneous and non-cutaneous drug delivery
GB2586475A (en) * 2019-08-20 2021-02-24 Innoture Ip Ltd Methods
CN115734798A (zh) 2020-04-28 2023-03-03 提克纳有限责任公司 微针组件
CN111991344B (zh) * 2020-09-28 2023-01-13 四川大学 一种适用于局部麻醉的微针贴片及其制备方法
CA3203391A1 (en) * 2020-12-30 2022-07-07 Song Li Methods and devices for inducement of sweat for medical diagnostics
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
KR20240054293A (ko) * 2021-09-15 2024-04-25 코스메드 파마소티컬 씨오 쩜 엘티디 약제를 도포한 마이크로니들 어레이
CN114699510B (zh) * 2021-12-29 2024-07-16 浙江湃肽生物有限公司 一种司美格鲁肽微针阵列及其制备方法
WO2024192352A2 (en) * 2023-03-16 2024-09-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biodissolvable microneedle array-metal-organic framework-vaccine biocomposites for effective skin immunization and manufacturing thereof
CN120897774A (zh) * 2023-03-30 2025-11-04 株式会社村田制作所 微针装置以及给药/反应物抽吸方法
CN119462417A (zh) * 2023-08-10 2025-02-18 中科中山药物创新研究院 药物包合物共晶、组合物、其制备方法和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585398A (en) * 1994-07-15 1996-12-17 Ernst; Amy A. Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use
ATE314092T1 (de) * 1997-09-26 2006-01-15 Noven Pharma Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen
EP1263413B1 (en) * 2000-03-09 2006-05-24 Ohio State University Research Foundation Method of preparing solid dispersions
US6455066B1 (en) * 2000-03-10 2002-09-24 Epicept Corporation Intradermal-penetration agents for topical local anesthetic administration
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
MXPA05000597A (es) 2002-07-19 2005-04-28 3M Innovative Properties Co Dispositivos de microaguja y aparatos de administracion por microaguja.
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
WO2005123173A1 (en) 2004-06-10 2005-12-29 3M Innovative Properties Company Patch application device and kit
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
WO2006138719A2 (en) * 2005-06-17 2006-12-28 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
JP2007089792A (ja) 2005-09-28 2007-04-12 Nano Device & System Research Inc 経皮投与装置
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
JP5298011B2 (ja) * 2007-05-15 2013-09-25 久光製薬株式会社 マイクロニードルのコーティング方法
CN101336895B (zh) * 2008-08-21 2010-08-25 董萍 一种碱化固液双态表皮快速麻醉纳米乳及其制备方法
US8834423B2 (en) * 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US10800040B1 (en) 2017-12-14 2020-10-13 Amazon Technologies, Inc. Simulation-real world feedback loop for learning robotic control policies

Also Published As

Publication number Publication date
WO2012122163A1 (en) 2012-09-13
EP2683359B1 (en) 2015-04-22
KR20140010425A (ko) 2014-01-24
US20140066843A1 (en) 2014-03-06
CN103429222A (zh) 2013-12-04
AU2012225609B2 (en) 2015-10-01
JP2014514022A (ja) 2014-06-19
DK2683359T3 (en) 2015-07-20
CA2829354C (en) 2020-09-29
EP2683359A1 (en) 2014-01-15
ES2542012T3 (es) 2015-07-29
KR102058978B1 (ko) 2019-12-24
AU2012225609A1 (en) 2013-10-10
CN103429222B (zh) 2015-09-09
CA2829354A1 (en) 2012-09-13
US20180344631A1 (en) 2018-12-06
BR112013022955A2 (pt) 2016-12-06

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