JP5940731B2 - S−アリル−l−システインを有効成分として含む眼疾患予防または治療用組成物、およびこれを含む医薬製剤 - Google Patents

S−アリル−l−システインを有効成分として含む眼疾患予防または治療用組成物、およびこれを含む医薬製剤 Download PDF

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JP5940731B2
JP5940731B2 JP2015527392A JP2015527392A JP5940731B2 JP 5940731 B2 JP5940731 B2 JP 5940731B2 JP 2015527392 A JP2015527392 A JP 2015527392A JP 2015527392 A JP2015527392 A JP 2015527392A JP 5940731 B2 JP5940731 B2 JP 5940731B2
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composition
preventing
cysteine
allyl
macular degeneration
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JP2015528825A (ja
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べ キム、ソオン
べ キム、ソオン
ソオン キム、クワン
ソオン キム、クワン
べ キム、ワン
べ キム、ワン
チャン クワク、ウィエ
チャン クワク、ウィエ
トゥク チョン、スン
トゥク チョン、スン
ヤン ヨオン、ヒュン
ヤン ヨオン、ヒュン
ピョ チャン、ヤン
ピョ チャン、ヤン
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Pharmaking Co Ltd
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Pharmaking Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2015527392A 2012-08-17 2013-08-19 S−アリル−l−システインを有効成分として含む眼疾患予防または治療用組成物、およびこれを含む医薬製剤 Active JP5940731B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020120089857A KR101423631B1 (ko) 2012-08-17 2012-08-17 에스-알릴엘-시스테인을 유효성분으로 포함하는 안질환 예방 또는 치료용 조성물 및 이를 포함하는 의약제제
KR10-2012-0089857 2012-08-17
PCT/KR2013/007420 WO2014027865A1 (fr) 2012-08-17 2013-08-19 Composition contenant comme principe actif de la s-allyl-l-cystéine et destinée à prévenir ou à traiter des maladies oculaires, et formulation pharmaceutique contenant cette composition

Publications (2)

Publication Number Publication Date
JP2015528825A JP2015528825A (ja) 2015-10-01
JP5940731B2 true JP5940731B2 (ja) 2016-06-29

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JP2015527392A Active JP5940731B2 (ja) 2012-08-17 2013-08-19 S−アリル−l−システインを有効成分として含む眼疾患予防または治療用組成物、およびこれを含む医薬製剤

Country Status (7)

Country Link
US (1) US9326960B2 (fr)
EP (1) EP2886112A4 (fr)
JP (1) JP5940731B2 (fr)
KR (1) KR101423631B1 (fr)
CN (1) CN104540506A (fr)
RU (1) RU2605618C2 (fr)
WO (1) WO2014027865A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2972329T3 (es) * 2015-12-17 2024-06-12 Link Genomics Inc Supresor de neovascularización coroidea o supresor de formación de drusas y método para evaluar o detectar las mismas
TWI715864B (zh) * 2018-09-05 2021-01-11 趙效明 用於預防或治療由視網膜缺血引起的疾病、病症或病況的方法
KR102165845B1 (ko) * 2018-09-18 2020-10-15 안국건강 주식회사 청색광에 의한 눈피로 개선용 조성물
EP3934660A4 (fr) * 2019-03-05 2022-11-23 Cornell University Compositions de matière présentant une activité pour éliminer la lipofuscine de cellules rétiniennes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2875308B2 (ja) 1989-11-22 1999-03-31 湧永製薬株式会社 S−アリルシステイン高濃度含有組成物の製造方法
US5596011A (en) * 1995-04-06 1997-01-21 Repine; Karen M. Method for the treatment of macular degeneration
US6866864B2 (en) * 2000-03-20 2005-03-15 Ahmed Mousa Compositions and methods of use in the treatment of angiogenesis and vascular-related disorders
WO2002041837A2 (fr) * 2000-11-22 2002-05-30 Rxkinetix, Inc. Traitement de mucosite
WO2005077176A1 (fr) 2004-02-11 2005-08-25 The Trustees Of Columbia University In The City Of New York Composes anthocyaniniques et procedes d'utilisation correspondants
EP1778207A2 (fr) * 2004-08-18 2007-05-02 Sytera Inc. Compositions combinees avec derives de 13-cis-retinyle et leur utilisation pour le traitement des etats ophtalmiques
DK2110141T3 (da) * 2007-01-31 2013-06-17 Sanwa Kagaku Kenkyusho Co Middel til beskyttelse af retinalnerve eller synsnerve
CN101467991B (zh) * 2007-08-02 2012-02-01 复旦大学 烯丙基半胱氨酸及其类似物在制备治疗心肌损伤药物中的用途
KR101188746B1 (ko) * 2009-09-23 2012-10-11 주식회사파마킹 에스-알릴-엘-시스테인을 유효성분으로 포함하는 위장질환 예방 또는 치료용 조성물
CN102077965A (zh) * 2010-12-14 2011-06-01 吕昌龙 一种制备黑大蒜及从中提取活性物质的方法
CN104415212A (zh) * 2013-08-27 2015-03-18 北京继开德铭医药科技有限公司 大蒜总多糖和含硫氨基酸类的组合物的抗皮肤脱屑及瘙痒用途

Also Published As

Publication number Publication date
WO2014027865A1 (fr) 2014-02-20
KR101423631B1 (ko) 2014-07-25
RU2015107235A (ru) 2016-10-20
US20150231100A1 (en) 2015-08-20
CN104540506A (zh) 2015-04-22
EP2886112A4 (fr) 2015-12-30
EP2886112A1 (fr) 2015-06-24
RU2605618C2 (ru) 2016-12-27
US9326960B2 (en) 2016-05-03
JP2015528825A (ja) 2015-10-01
KR20140023659A (ko) 2014-02-27

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