JP5922592B2 - 血清アミロイドp成分に特異的な抗原結合タンパク質 - Google Patents

血清アミロイドp成分に特異的な抗原結合タンパク質 Download PDF

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JP5922592B2
JP5922592B2 JP2012555403A JP2012555403A JP5922592B2 JP 5922592 B2 JP5922592 B2 JP 5922592B2 JP 2012555403 A JP2012555403 A JP 2012555403A JP 2012555403 A JP2012555403 A JP 2012555403A JP 5922592 B2 JP5922592 B2 JP 5922592B2
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sap
seq
antibody
human
antigen binding
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JP2013521252A (ja
JP2013521252A5 (OSRAM
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ビンダー,テジンダー,カウル
フォード,スザンナ,カレン
ゲルマシェウスキー,フォルカー
ルイス,アラン,ピーター
ピープス,マーク,ブライアン
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Glaxo Group Ltd
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/18Growth factors; Growth regulators
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Diabetes (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2012555403A 2010-03-03 2011-03-01 血清アミロイドp成分に特異的な抗原結合タンパク質 Expired - Fee Related JP5922592B2 (ja)

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US30995710P 2010-03-03 2010-03-03
US61/309,957 2010-03-03
PCT/EP2011/053038 WO2011107480A1 (en) 2010-03-03 2011-03-01 Antigen binding proteins specific for serum amyloid p component

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JP2013521252A JP2013521252A (ja) 2013-06-10
JP2013521252A5 JP2013521252A5 (OSRAM) 2014-03-20
JP5922592B2 true JP5922592B2 (ja) 2016-05-24

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JP2016020718A Expired - Fee Related JP6236478B2 (ja) 2010-03-03 2016-02-05 血清アミロイドp成分に特異的な抗原結合タンパク質

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CN103239713A (zh) * 2013-05-28 2013-08-14 东南大学 一种糖尿病肾病微炎症小鼠模型的建立方法
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US11266745B2 (en) 2017-02-08 2022-03-08 Imaginab, Inc. Extension sequences for diabodies
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CN116925216B (zh) * 2022-04-11 2024-09-24 东莞市朋志生物科技有限公司 抗血清淀粉样蛋白a抗体、检测血清淀粉样蛋白a的试剂和试剂盒

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HRP20161096T1 (hr) 2016-11-04
LT2542261T (lt) 2016-09-26
LT3025729T (lt) 2018-12-10
EP2542261A1 (en) 2013-01-09
CL2012002418A1 (es) 2013-03-08
SI2542261T1 (sl) 2016-11-30
AU2011223048C1 (en) 2018-06-21
HRP20181666T1 (hr) 2018-12-14
SMT201600337B (it) 2016-11-10
CN102858371A (zh) 2013-01-02
JO3188B1 (ar) 2018-03-08
TW201143789A (en) 2011-12-16
HK1173959A1 (zh) 2013-05-31
RS55133B1 (sr) 2016-12-30
CY1118046T1 (el) 2017-05-17
JP6236478B2 (ja) 2017-11-22
UA108227C2 (xx) 2015-04-10
DOP2012000232A (es) 2013-01-15
MX340350B (es) 2016-07-06
EA026375B1 (ru) 2017-04-28
EP3025729B1 (en) 2018-09-12
SMT201800633T1 (it) 2019-01-11
ES2699078T3 (es) 2019-02-07
EP2542261B1 (en) 2016-07-06
JP2013521252A (ja) 2013-06-10
HUE028960T2 (en) 2017-01-30
ZA201206529B (en) 2018-12-19
IL221418A (en) 2017-03-30
WO2011107480A1 (en) 2011-09-09
KR101817265B1 (ko) 2018-01-10
ME02491B (me) 2017-02-20
DK2542261T3 (en) 2016-09-19
IL251031A0 (en) 2017-04-30
SG183316A1 (en) 2012-09-27
NZ601763A (en) 2014-08-29
CY1120803T1 (el) 2019-12-11
EP3025729A1 (en) 2016-06-01
MY159255A (en) 2016-12-30
UY33258A (es) 2011-09-30
ES2593454T3 (es) 2016-12-09
CA2789557A1 (en) 2011-09-09
PT3025729T (pt) 2018-11-30
PH12012501743A1 (en) 2012-11-12
IL251031A (en) 2017-11-30
BR112012021926A2 (pt) 2020-08-25
AU2011223048A1 (en) 2012-10-04
TWI558409B (zh) 2016-11-21
MA34135B1 (fr) 2013-04-03
DK3025729T3 (en) 2018-11-26
EA201290671A1 (ru) 2013-05-30
PT2542261T (pt) 2016-09-27
JP2016154535A (ja) 2016-09-01
AR080432A1 (es) 2012-04-11
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CN102858371B (zh) 2017-03-01
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RS57708B1 (sr) 2018-12-31
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SI3025729T1 (sl) 2018-11-30
PE20130040A1 (es) 2013-02-09
HK1223292A1 (en) 2017-07-28
CO6602134A2 (es) 2013-01-18
MX2012010129A (es) 2012-09-12
CR20120491A (es) 2013-02-20
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