MX340350B - Proteinas de union a antigeno especificas para el componente p amiloide serico. - Google Patents

Proteinas de union a antigeno especificas para el componente p amiloide serico.

Info

Publication number
MX340350B
MX340350B MX2012010129A MX2012010129A MX340350B MX 340350 B MX340350 B MX 340350B MX 2012010129 A MX2012010129 A MX 2012010129A MX 2012010129 A MX2012010129 A MX 2012010129A MX 340350 B MX340350 B MX 340350B
Authority
MX
Mexico
Prior art keywords
antigen binding
binding proteins
component
serum amyloid
proteins specific
Prior art date
Application number
MX2012010129A
Other languages
English (en)
Other versions
MX2012010129A (es
Inventor
Germaschewski Volker
Peter Lewis Alan
Brian Pepys Mark
Karen Ford Susannah
Kaur Bhinder Tejinder
Original Assignee
Glaxo Group Ltd *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43881068&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX340350(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd * filed Critical Glaxo Group Ltd *
Publication of MX2012010129A publication Critical patent/MX2012010129A/es
Publication of MX340350B publication Critical patent/MX340350B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a proteínas de unión a antígeno de tipo no múrido, la cual se une específicamente a SAP y compite para unirse a SAP con un anticuerpo de referencia el cual comprende una secuencia de la región variable de la cadena pesada de SEC ID NO: 7, y una secuencia de la región variable de la cadena ligera de SEC ID NO: 9.
MX2012010129A 2010-03-03 2011-03-01 Proteinas de union a antigeno especificas para el componente p amiloide serico. MX340350B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30995710P 2010-03-03 2010-03-03
PCT/EP2011/053038 WO2011107480A1 (en) 2010-03-03 2011-03-01 Antigen binding proteins specific for serum amyloid p component

Publications (2)

Publication Number Publication Date
MX2012010129A MX2012010129A (es) 2012-09-12
MX340350B true MX340350B (es) 2016-07-06

Family

ID=43881068

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012010129A MX340350B (es) 2010-03-03 2011-03-01 Proteinas de union a antigeno especificas para el componente p amiloide serico.

Country Status (39)

Country Link
EP (2) EP3025729B1 (es)
JP (2) JP5922592B2 (es)
KR (1) KR101817265B1 (es)
CN (1) CN102858371B (es)
AR (1) AR080432A1 (es)
AU (1) AU2011223048C1 (es)
BR (1) BR112012021926A2 (es)
CA (1) CA2789557A1 (es)
CL (1) CL2012002418A1 (es)
CO (1) CO6602134A2 (es)
CR (1) CR20120491A (es)
CY (2) CY1118046T1 (es)
DK (2) DK2542261T3 (es)
DO (1) DOP2012000232A (es)
EA (1) EA026375B1 (es)
ES (2) ES2699078T3 (es)
HR (2) HRP20161096T1 (es)
HU (1) HUE028960T2 (es)
IL (2) IL221418A (es)
JO (1) JO3188B1 (es)
LT (2) LT2542261T (es)
MA (1) MA34135B1 (es)
ME (1) ME02491B (es)
MX (1) MX340350B (es)
MY (1) MY159255A (es)
NZ (1) NZ601763A (es)
PE (1) PE20130040A1 (es)
PH (1) PH12012501743A1 (es)
PL (2) PL3025729T3 (es)
PT (2) PT3025729T (es)
RS (2) RS57708B1 (es)
SG (2) SG183316A1 (es)
SI (2) SI2542261T1 (es)
SM (2) SMT201800633T1 (es)
TW (1) TWI558409B (es)
UA (1) UA108227C2 (es)
UY (1) UY33258A (es)
WO (1) WO2011107480A1 (es)
ZA (1) ZA201206529B (es)

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EP2506876B1 (en) 2009-12-02 2016-10-12 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
EA031025B1 (ru) * 2012-12-21 2018-11-30 Сиэтл Дженетикс, Инк. Антитела против ntb-a и связанные с ними композиции и способы
CN103239713A (zh) * 2013-05-28 2013-08-14 东南大学 一种糖尿病肾病微炎症小鼠模型的建立方法
US9737505B2 (en) * 2014-04-29 2017-08-22 Glaxosmithkline Intellectual Property Development Limited Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline
GB201407506D0 (en) 2014-04-29 2014-06-11 Glaxosmithkline Ip Dev Ltd Novel compound
WO2017027325A1 (en) 2015-08-07 2017-02-16 Imaginab, Inc. Antigen binding constructs to target molecules
US11266745B2 (en) 2017-02-08 2022-03-08 Imaginab, Inc. Extension sequences for diabodies
WO2019185502A1 (en) 2018-03-26 2019-10-03 Glaxosmithkline Intellectual Property Development Limited Antibodies comprising methionine sulfoxide at the ch2-ch3 interface
CN116925216B (zh) * 2022-04-11 2024-09-24 东莞市朋志生物科技有限公司 抗血清淀粉样蛋白a抗体、检测血清淀粉样蛋白a的试剂和试剂盒

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Also Published As

Publication number Publication date
ES2699078T3 (es) 2019-02-07
BR112012021926A2 (pt) 2020-08-25
ES2593454T3 (es) 2016-12-09
EA026375B1 (ru) 2017-04-28
PE20130040A1 (es) 2013-02-09
CO6602134A2 (es) 2013-01-18
AU2011223048C1 (en) 2018-06-21
HUE028960T2 (en) 2017-01-30
SMT201800633T1 (it) 2019-01-11
HK1223292A1 (en) 2017-07-28
PL2542261T3 (pl) 2016-12-30
JP6236478B2 (ja) 2017-11-22
CA2789557A1 (en) 2011-09-09
SI2542261T1 (sl) 2016-11-30
SI3025729T1 (sl) 2018-11-30
DK2542261T3 (en) 2016-09-19
CY1120803T1 (el) 2019-12-11
JP5922592B2 (ja) 2016-05-24
DOP2012000232A (es) 2013-01-15
SMT201600337B (it) 2016-11-10
AU2011223048A1 (en) 2012-10-04
PT3025729T (pt) 2018-11-30
TW201143789A (en) 2011-12-16
ME02491B (me) 2017-02-20
MY159255A (en) 2016-12-30
CN102858371B (zh) 2017-03-01
EP3025729B1 (en) 2018-09-12
NZ601763A (en) 2014-08-29
HRP20181666T1 (hr) 2018-12-14
EA201290671A1 (ru) 2013-05-30
HK1173959A1 (zh) 2013-05-31
EP2542261A1 (en) 2013-01-09
AR080432A1 (es) 2012-04-11
AU2011223048B2 (en) 2013-12-19
MA34135B1 (fr) 2013-04-03
SG10201500382SA (en) 2015-03-30
TWI558409B (zh) 2016-11-21
DK3025729T3 (en) 2018-11-26
JP2016154535A (ja) 2016-09-01
LT3025729T (lt) 2018-12-10
IL251031A0 (en) 2017-04-30
EP2542261B1 (en) 2016-07-06
IL221418A (en) 2017-03-30
UY33258A (es) 2011-09-30
RS55133B1 (sr) 2016-12-30
CN102858371A (zh) 2013-01-02
LT2542261T (lt) 2016-09-26
RS57708B1 (sr) 2018-12-31
HRP20161096T1 (hr) 2016-11-04
IL221418A0 (en) 2012-10-31
KR101817265B1 (ko) 2018-01-10
SG183316A1 (en) 2012-09-27
PH12012501743A1 (en) 2012-11-12
WO2011107480A1 (en) 2011-09-09
MX2012010129A (es) 2012-09-12
ZA201206529B (en) 2018-12-19
JO3188B1 (ar) 2018-03-08
EP3025729A1 (en) 2016-06-01
PT2542261T (pt) 2016-09-27
PL3025729T3 (pl) 2019-02-28
CL2012002418A1 (es) 2013-03-08
UA108227C2 (xx) 2015-04-10
JP2013521252A (ja) 2013-06-10
CR20120491A (es) 2013-02-20
KR20130027483A (ko) 2013-03-15
IL251031A (en) 2017-11-30
CY1118046T1 (el) 2017-05-17

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