TN2011000150A1 - Anti cxcr4 antibodies and their use for the treatment of cancer - Google Patents

Anti cxcr4 antibodies and their use for the treatment of cancer

Info

Publication number
TN2011000150A1
TN2011000150A1 TN2011000150A TN2011000150A TN2011000150A1 TN 2011000150 A1 TN2011000150 A1 TN 2011000150A1 TN 2011000150 A TN2011000150 A TN 2011000150A TN 2011000150 A TN2011000150 A TN 2011000150A TN 2011000150 A1 TN2011000150 A1 TN 2011000150A1
Authority
TN
Tunisia
Prior art keywords
antibodies
cancer
treatment
cxcr4
cxcr4 antibodies
Prior art date
Application number
TN2011000150A
Other languages
French (fr)
Inventor
Caussanel Veronique Grenier
Hamour Christine Klinguer
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2009/062787 external-priority patent/WO2010037831A1/en
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of TN2011000150A1 publication Critical patent/TN2011000150A1/en

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a novel isolated antibody, or the derived compounds or functional fragments of same, capable of binding to CXCR4 but also of inducing conformational changed of the CXCR4 homodimers and/or heterodimers. More particularly, the present invention relates to the 414H5 and 515H7 antibodies, specific to the CXCR4 protein, as well as their use for the treatment of cancer. Pharmaceutical compositions composed of such antibodies and a process for the selection of such antibodies are also covered.
TN2011000150A 2009-10-01 2011-03-28 Anti cxcr4 antibodies and their use for the treatment of cancer TN2011000150A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2009/062787 WO2010037831A1 (en) 2008-10-01 2009-10-01 Anti cxcr4 antibodies and their use for the treatment of cancer

Publications (1)

Publication Number Publication Date
TN2011000150A1 true TN2011000150A1 (en) 2012-09-05

Family

ID=55024436

Family Applications (1)

Application Number Title Priority Date Filing Date
TN2011000150A TN2011000150A1 (en) 2009-10-01 2011-03-28 Anti cxcr4 antibodies and their use for the treatment of cancer

Country Status (1)

Country Link
TN (1) TN2011000150A1 (en)

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