JP5916288B2 - 自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤 - Google Patents

自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤 Download PDF

Info

Publication number
JP5916288B2
JP5916288B2 JP2011024040A JP2011024040A JP5916288B2 JP 5916288 B2 JP5916288 B2 JP 5916288B2 JP 2011024040 A JP2011024040 A JP 2011024040A JP 2011024040 A JP2011024040 A JP 2011024040A JP 5916288 B2 JP5916288 B2 JP 5916288B2
Authority
JP
Japan
Prior art keywords
innate immunity
lactic acid
royal jelly
acid bacteria
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2011024040A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012162488A (ja
Inventor
啓子 片岡
啓子 片岡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MORIKAWA KENKODO CO., LTD.
Original Assignee
MORIKAWA KENKODO CO., LTD.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MORIKAWA KENKODO CO., LTD. filed Critical MORIKAWA KENKODO CO., LTD.
Priority to JP2011024040A priority Critical patent/JP5916288B2/ja
Priority to CN201280007462.5A priority patent/CN103347527B/zh
Priority to PCT/JP2012/052474 priority patent/WO2012108347A1/ja
Publication of JP2012162488A publication Critical patent/JP2012162488A/ja
Application granted granted Critical
Publication of JP5916288B2 publication Critical patent/JP5916288B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L21/00Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A23L21/20Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/121Brevis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Polymers & Plastics (AREA)
  • Insects & Arthropods (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011024040A 2011-02-07 2011-02-07 自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤 Active JP5916288B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2011024040A JP5916288B2 (ja) 2011-02-07 2011-02-07 自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤
CN201280007462.5A CN103347527B (zh) 2011-02-07 2012-02-03 蜂王浆以乳酸菌发酵的发酵物在制备作为自然免疫活性化剂中的应用
PCT/JP2012/052474 WO2012108347A1 (ja) 2011-02-07 2012-02-03 自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011024040A JP5916288B2 (ja) 2011-02-07 2011-02-07 自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤

Publications (2)

Publication Number Publication Date
JP2012162488A JP2012162488A (ja) 2012-08-30
JP5916288B2 true JP5916288B2 (ja) 2016-05-11

Family

ID=46638563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011024040A Active JP5916288B2 (ja) 2011-02-07 2011-02-07 自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤

Country Status (3)

Country Link
JP (1) JP5916288B2 (zh)
CN (1) CN103347527B (zh)
WO (1) WO2012108347A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3255140B1 (en) * 2015-02-06 2024-10-16 Genome Pharmaceuticals Institute Co., Ltd. Lactic acid bacteria, natural immunoactivator and infection preventative/therapeutic derived from said lactic acid bacteria, and food/beverage
WO2016204120A1 (ja) * 2015-06-15 2016-12-22 乃 玉井 竹発酵抽出物の製造方法及び免疫賦活剤
JP6985666B2 (ja) * 2016-12-27 2021-12-22 アピ株式会社 ローヤルゼリー素材の製造方法、ローヤルゼリー素材、ローヤルゼリー含有飲食品、及びローヤルゼリー含有化粧料
WO2021033726A1 (ja) * 2019-08-22 2021-02-25 株式会社山田養蜂場本社 変換方法、変換剤、ローヤルゼリー組成物の製造方法、及びラクトバチルス属細菌
CN112352937A (zh) * 2020-11-18 2021-02-12 北京中蜜科技发展有限公司 一种蜂王浆双歧杆菌粉的制备方法
CN113712888B (zh) * 2021-09-06 2023-05-12 浙江辰海生命科学有限公司 蜂王浆分离液发酵物、含其皮肤外用剂及制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2918564B2 (ja) * 1989-05-12 1999-07-12 日本製紙株式会社 免疫増強剤
JP2909960B2 (ja) * 1995-11-02 1999-06-23 大槌町漁業協同組合 海藻類芽株の粉末の製造方法
JP3295779B2 (ja) * 2000-04-05 2002-06-24 株式会社日健総本社 抗癌性物質
KR100594353B1 (ko) * 2002-05-28 2006-07-03 주식회사 엠디바이오알파 신규한 인삼잎 및 줄기 다당체, 그 제조방법 및 그를활성성분으로 함유하는 항암제 및 항암보조제 조성물
CN1685886A (zh) * 2005-06-03 2005-10-26 余内逊 一种桑楂琥铬糖参王降糖助睡益肠夜酸乳制备方法
CN1685887A (zh) * 2005-06-03 2005-10-26 余内逊 一种微米糖参珍琥王降糖安神夜酸乳制备方法
CN1685885A (zh) * 2005-06-03 2005-10-26 余内逊 一种桑楂琥铬糖参王降糖助睡益肠夜酸豆奶制备方法
CN1685901A (zh) * 2005-06-03 2005-10-26 余内逊 一种微米糖参珍琥王降糖安神夜酸豆奶制备方法
CN100379346C (zh) * 2005-11-22 2008-04-09 余内逊 一种微米糖参绿猴王西天斗蜂胶滋阴养胃酸奶制备方法
CN1785051A (zh) * 2005-11-22 2006-06-14 余内逊 一种微米糖参绿猴王西天斗蜂胶滋阴养胃酸豆奶制备方法
CN100362925C (zh) * 2006-01-12 2008-01-23 余内逊 一种微米糖参百仙铁皮石斛王养阴消疲酸奶制备方法
US8313779B2 (en) * 2007-04-10 2012-11-20 Genome Pharmaceuticals Institute Co., Ltd. Evaluation method and screening method for substance having action of activating/suppressing innate immunity, agent and food product for activating/suppressing innate immune mechanism and method for producing the same
JP5408927B2 (ja) * 2007-08-10 2014-02-05 森川健康堂株式会社 γ−アミノ酪酸の製造方法
JP5592640B2 (ja) * 2009-11-30 2014-09-17 アピ株式会社 乳酸菌発酵ローヤルゼリーを含有する抗ストレス剤、その製造方法、視床下部−下垂体−副腎皮質系の活動抑制剤、及び交感神経−副腎髄質系の活動抑制剤
JP5502449B2 (ja) * 2009-12-18 2014-05-28 株式会社 杉養蜂園 腸内フローラバランス改善剤及びその製造方法

Also Published As

Publication number Publication date
JP2012162488A (ja) 2012-08-30
CN103347527A (zh) 2013-10-09
CN103347527B (zh) 2015-09-23
WO2012108347A1 (ja) 2012-08-16

Similar Documents

Publication Publication Date Title
JP5916288B2 (ja) 自然免疫促進作用が増強された自然免疫活性化剤の製造方法及びその製造方法で製造されたローヤルゼリー由来の自然免疫活性化剤
KR100514592B1 (ko) 공역화 리놀렌산을 생산하는 신규한 균주, 이를 함유하는 캡슐제 및 이를 이용한 기능성 식품
WO2019212997A1 (en) Compositions and methods for biosynthetic preparation of urolithin compounds and use thereof
JP5592640B2 (ja) 乳酸菌発酵ローヤルゼリーを含有する抗ストレス剤、その製造方法、視床下部−下垂体−副腎皮質系の活動抑制剤、及び交感神経−副腎髄質系の活動抑制剤
CN111212575A (zh) 肌肉增量用组合物
US9895400B2 (en) Composition and use of Lactobacillus reuteri GMNL-263 in decreasing blood lipid levels
JP5740072B2 (ja) β−1,3−1,6−D−グルカンを用いたストレス緩和剤
KR20120112510A (ko) 경구용 dna 손상 수복 촉진제 및 엘라스타아제 활성 억제제
CN116076728B (zh) 促进双歧杆菌生长的组合物
Reshetnik et al. Healthy food products with probiotic and prebiotic properties
CN113499401A (zh) 一种治疗阿尔茨海默病的药物组合物及其制备方法和应用
JP2005013211A (ja) 乳酸菌含有食品組成物
JP5943406B2 (ja) ビフィズス菌または乳酸菌の生存維持用組成物
JP4716770B2 (ja) 免疫賦活・アレルギー改善剤の製造方法
JP2021505211A (ja) 腎臓疾患進行抑制及び予防用プロバイオティクス及びこれを含む腎臓疾患進行抑制及び予防用組成物
CN112616932A (zh) 保护口腔健康的羊奶片及其制备方法
CN111065274A (zh) 用于促进血液中的氨基酸浓度提高的发酵乳
JP5502449B2 (ja) 腸内フローラバランス改善剤及びその製造方法
JP3829107B2 (ja) 免疫反応性NO合成を誘導するiNOS酵素を刺激する組成剤およびその製造方法
WO2018169011A1 (ja) 腸内フローラバランス改善用食品組成物及び腸内フローラバランス改善剤
KR101878525B1 (ko) Qol 개선 또는 지속제
JP7165363B2 (ja) 免疫賦活組成物
Kazemi et al. Evaluation the effect of royal jelly on the growth of two members of gut microbiota; Bacteroides fragillis and Bacteroides thetaiotaomicron.
JP2018154612A (ja) F/b比低下用食品組成物、f/b比低下剤、アッカーマンシア・ムシニフィラ菌占有率増加用食品組成物及びアッカーマンシア・ムシニフィラ菌占有率増加剤
KR20100100827A (ko) 아디포넥틴 분비 촉진 및/또는 감소 억제제

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140129

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20140129

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150127

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150330

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20150408

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20150408

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150825

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151021

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20160316

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160405

R150 Certificate of patent or registration of utility model

Ref document number: 5916288

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250