JP5890095B2 - カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法 - Google Patents
カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法 Download PDFInfo
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- JP5890095B2 JP5890095B2 JP2010516041A JP2010516041A JP5890095B2 JP 5890095 B2 JP5890095 B2 JP 5890095B2 JP 2010516041 A JP2010516041 A JP 2010516041A JP 2010516041 A JP2010516041 A JP 2010516041A JP 5890095 B2 JP5890095 B2 JP 5890095B2
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- nucleic acid
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
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- Molecular Biology (AREA)
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- Microbiology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
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- Biophysics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92968507P | 2007-07-09 | 2007-07-09 | |
| US60/929,685 | 2007-07-09 | ||
| PCT/US2008/008394 WO2009009054A1 (en) | 2007-07-09 | 2008-07-09 | Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014089131A Division JP2014148533A (ja) | 2007-07-09 | 2014-04-23 | カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010533178A JP2010533178A (ja) | 2010-10-21 |
| JP2010533178A5 JP2010533178A5 (https=) | 2011-04-14 |
| JP5890095B2 true JP5890095B2 (ja) | 2016-03-22 |
Family
ID=40228915
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010516041A Expired - Fee Related JP5890095B2 (ja) | 2007-07-09 | 2008-07-09 | カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法 |
| JP2014089131A Pending JP2014148533A (ja) | 2007-07-09 | 2014-04-23 | カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014089131A Pending JP2014148533A (ja) | 2007-07-09 | 2014-04-23 | カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090053299A1 (https=) |
| EP (1) | EP2175835B1 (https=) |
| JP (2) | JP5890095B2 (https=) |
| KR (2) | KR101570886B1 (https=) |
| CN (2) | CN101801344A (https=) |
| AU (1) | AU2008275713B2 (https=) |
| BR (1) | BRPI0814558A2 (https=) |
| CA (1) | CA2692546C (https=) |
| EA (1) | EA201070050A1 (https=) |
| IL (1) | IL203204B (https=) |
| MX (1) | MX2010000166A (https=) |
| NZ (1) | NZ582414A (https=) |
| SG (1) | SG182994A1 (https=) |
| WO (1) | WO2009009054A1 (https=) |
| ZA (1) | ZA201000038B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5573111B2 (ja) * | 2009-11-06 | 2014-08-20 | ライオン株式会社 | イソプロピルメチルフェノール含有液体口腔用組成物 |
| US20110182976A1 (en) * | 2010-01-28 | 2011-07-28 | National Taiwan Ocean University | Lipoplex-patch based dna vaccine |
| CN102858367B (zh) * | 2010-02-26 | 2014-12-17 | 国立大学法人长崎大学 | 抗原或药物递送复合物 |
| RS63890B1 (sr) * | 2010-08-31 | 2023-02-28 | Glaxosmithkline Biologicals Sa | Mali lipozomi za isporuku rnk koja kodira imunogen |
| US8932575B2 (en) | 2010-09-21 | 2015-01-13 | University Of Miami | Compositions and methods for inducing migration by dendritic cells and an immune response |
| WO2012040266A2 (en) * | 2010-09-24 | 2012-03-29 | University Of Miami | Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines |
| US20140120157A1 (en) | 2012-09-19 | 2014-05-01 | Georgetown University | Targeted liposomes |
| SG2013014170A (en) * | 2012-09-19 | 2014-04-28 | Univ Georgetown | Targeted liposomes |
| CN103405386B (zh) * | 2012-09-21 | 2016-05-18 | 上海泽润生物科技有限公司 | 一种脂质体的制备方法及制作脂质体佐剂的方法 |
| WO2014159917A2 (en) | 2013-03-14 | 2014-10-02 | Georgetown University | Treatment for exposure to nerve agent |
| CN105726485B (zh) * | 2016-03-24 | 2019-08-06 | 东华大学 | 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法 |
| WO2020117715A1 (en) | 2018-12-03 | 2020-06-11 | Board Of Regents, The University Of Texas System | Oligo-benzamide analogs and their use in cancer treatment |
| CN111840538A (zh) * | 2020-05-29 | 2020-10-30 | 中山大学 | 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用 |
| CN117883382B (zh) * | 2023-11-27 | 2025-02-14 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4957735A (en) * | 1984-06-12 | 1990-09-18 | The University Of Tennessee Research Corporation | Target-sensitive immunoliposomes- preparation and characterization |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5688488A (en) * | 1989-04-03 | 1997-11-18 | Purdue Research Foundation | Composition and method for tumor imaging |
| US5753258A (en) * | 1990-10-19 | 1998-05-19 | University Of Florida | Artificial viral envelopes |
| US6099842A (en) * | 1990-12-03 | 2000-08-08 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin |
| DE69332485T2 (de) * | 1992-08-11 | 2003-11-13 | The President And Fellows Of Harvard College, Cambridge | Immunmodulierende peptide |
| US5786214A (en) * | 1994-12-15 | 1998-07-28 | Spinal Cord Society | pH-sensitive immunoliposomes and method of gene delivery to the mammalian central nervous system |
| FR2730637B1 (fr) * | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| CA2245835A1 (en) * | 1995-06-14 | 1997-01-03 | The Regents Of The University Of California | Novel high affinity human antibodies to tumor antigens |
| US6210707B1 (en) * | 1996-11-12 | 2001-04-03 | The Regents Of The University Of California | Methods of forming protein-linked lipidic microparticles, and compositions thereof |
| JP2001510457A (ja) * | 1996-11-12 | 2001-07-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | インビボ送達に有効な、脂質―核酸複合体の安定な製剤の調製 |
| US6794128B2 (en) * | 1998-04-24 | 2004-09-21 | The Regents Of The University Of California | Methods of selecting internalizing antibodies |
| US20030022854A1 (en) * | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
| US9034329B2 (en) * | 1999-02-22 | 2015-05-19 | Georgetown University | Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof |
| ATE511543T1 (de) | 1999-02-22 | 2011-06-15 | Univ Georgetown | Immunoliposome mit einem targeting- antikörperfragment zur systemischen genverabreichung |
| US7780882B2 (en) | 1999-02-22 | 2010-08-24 | Georgetown University | Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent |
| US20020103165A1 (en) * | 2000-02-29 | 2002-08-01 | Alliance Pharmaceutical Corp., | Engineered spray-dried lipid-based microparticles for cellular targeting |
| PT1633327E (pt) | 2003-06-04 | 2010-11-08 | Univ Georgetown | Método para melhoramento da estabilidade e duração de armazenamento de complexos lipossomais |
| AU2006304790B2 (en) * | 2005-10-20 | 2013-06-27 | Georgetown University | Tumor-targeted nanodelivery systems to improve early MRI detection of cancer |
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2008
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- 2008-07-09 CN CN200880105375A patent/CN101801344A/zh active Pending
- 2008-07-09 BR BRPI0814558-0A2A patent/BRPI0814558A2/pt not_active Application Discontinuation
- 2008-07-09 CN CN201710070091.XA patent/CN106890142A/zh active Pending
- 2008-07-09 SG SG2012049664A patent/SG182994A1/en unknown
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|---|---|
| SG182994A1 (en) | 2012-08-30 |
| EP2175835A4 (en) | 2011-08-03 |
| NZ582414A (en) | 2012-09-28 |
| MX2010000166A (es) | 2010-04-27 |
| HK1143532A1 (zh) | 2011-01-07 |
| EA201070050A1 (ru) | 2010-10-29 |
| US20090053299A1 (en) | 2009-02-26 |
| CA2692546A1 (en) | 2009-01-15 |
| KR20150108948A (ko) | 2015-09-30 |
| JP2014148533A (ja) | 2014-08-21 |
| AU2008275713A1 (en) | 2009-01-15 |
| IL203204B (en) | 2018-05-31 |
| BRPI0814558A2 (pt) | 2015-01-06 |
| CN106890142A (zh) | 2017-06-27 |
| WO2009009054A1 (en) | 2009-01-15 |
| AU2008275713B2 (en) | 2014-08-07 |
| EP2175835B1 (en) | 2016-04-20 |
| KR20100044206A (ko) | 2010-04-29 |
| CN101801344A (zh) | 2010-08-11 |
| CA2692546C (en) | 2018-03-13 |
| KR101570886B1 (ko) | 2015-11-23 |
| JP2010533178A (ja) | 2010-10-21 |
| EP2175835A1 (en) | 2010-04-21 |
| ZA201000038B (en) | 2011-03-30 |
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