JP5885832B2 - ネプリライシン阻害剤 - Google Patents

ネプリライシン阻害剤 Download PDF

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JP5885832B2
JP5885832B2 JP2014513549A JP2014513549A JP5885832B2 JP 5885832 B2 JP5885832 B2 JP 5885832B2 JP 2014513549 A JP2014513549 A JP 2014513549A JP 2014513549 A JP2014513549 A JP 2014513549A JP 5885832 B2 JP5885832 B2 JP 5885832B2
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alkyl
alkylene
compound
coor
phenyl
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JP2014528903A (ja
JP2014528903A5 (enExample
Inventor
メリッサ フルーリー，
メリッサ フルーリー，
ローランド ジェンドロン，
ローランド ジェンドロン，
アダム ディー． ヒューズ，
アダム ディー． ヒューズ，
ジェーン シュミット，
ジェーン シュミット，
Original Assignee
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー
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    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
    • C07D231/26—1-Phenyl-3-methyl-5- pyrazolones, unsubstituted or substituted on the phenyl ring
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    • C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings

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