JP5883436B2 - 血液成分採取装置 - Google Patents
血液成分採取装置 Download PDFInfo
- Publication number
- JP5883436B2 JP5883436B2 JP2013510930A JP2013510930A JP5883436B2 JP 5883436 B2 JP5883436 B2 JP 5883436B2 JP 2013510930 A JP2013510930 A JP 2013510930A JP 2013510930 A JP2013510930 A JP 2013510930A JP 5883436 B2 JP5883436 B2 JP 5883436B2
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- blood
- plasma
- bag
- collection
- anticoagulant
- Prior art date
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- 239000012503 blood component Substances 0.000 title claims description 42
- 210000004369 blood Anatomy 0.000 claims description 162
- 239000008280 blood Substances 0.000 claims description 162
- 239000003146 anticoagulant agent Substances 0.000 claims description 65
- 229940127219 anticoagulant drug Drugs 0.000 claims description 65
- 238000005119 centrifugation Methods 0.000 claims description 17
- 239000000306 component Substances 0.000 claims description 17
- 239000007788 liquid Substances 0.000 claims description 8
- 238000012546 transfer Methods 0.000 claims description 7
- 210000002381 plasma Anatomy 0.000 description 140
- 238000000034 method Methods 0.000 description 65
- 230000008569 process Effects 0.000 description 59
- 238000003860 storage Methods 0.000 description 29
- 230000001133 acceleration Effects 0.000 description 25
- 210000000265 leukocyte Anatomy 0.000 description 23
- 230000007246 mechanism Effects 0.000 description 17
- 210000003743 erythrocyte Anatomy 0.000 description 13
- 238000012545 processing Methods 0.000 description 11
- 238000001914 filtration Methods 0.000 description 8
- 239000012530 fluid Substances 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 230000005856 abnormality Effects 0.000 description 5
- 230000009471 action Effects 0.000 description 5
- 238000001514 detection method Methods 0.000 description 5
- 238000012544 monitoring process Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 4
- 238000004891 communication Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000009825 accumulation Methods 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- 239000011347 resin Substances 0.000 description 3
- 229920005989 resin Polymers 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000037452 priming Effects 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 229920012485 Plasticized Polyvinyl chloride Polymers 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
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- 230000004048 modification Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
Description
Claims (2)
- ドナーから血液を採取する採血ライン(14a)と、
前記採血ライン(14a)に抗凝固剤を供給する抗凝固剤供給ライン(14c)と、
採取された血液を遠心分離して所定の血液成分を得る遠心分離器(120)と、
遠心分離して得られた血漿を貯留する血漿採取バッグ(122)と、
遠心分離して得られた濃厚血小板を一時的に貯留する中間バッグ(126a)と、
前記中間バッグ(126a)から移送される濃厚血小板を貯留する血小板採取バッグ(124)と、
前記中間バッグ(126a)と前記血小板採取バッグ(124)との間の送液ライン上に設けられ、前記濃厚血小板中の所定成分を除去するフィルター(130)と、
前記遠心分離器(120)と前記血漿採取バッグ(122)との間の流路を連通させる状態と、前記遠心分離器(120)と前記中間バッグ(126a)との間の流路を連通させる状態とを選択的に切り替える切替手段(36c、36e)と、
前記遠心分離器(120)及び前記切替手段(36c、36e)を駆動制御する制御部(26)と、
を有し、
前記制御部(26)は、
血液を前記採血ライン(14a)から前記遠心分離器(120)に導入して遠心分離を行うとともに遠心分離して得られた血漿を前記血漿採取バッグ(122)に移送する血漿採取工程と、
前記血漿採取工程の後に、遠心分離して得られた濃厚血小板を前記中間バッグ(126a)に移送する血小板移送工程と、
を少なくとも1サイクル行い、
第1サイクル時の前記血小板移送工程の前に、遠心分離して得られた血漿を所定量だけ前記中間バッグ(126a)に導入する血漿導入工程を行う、
ことを特徴とする血液成分採取装置(10)。 - 請求項1記載の血液成分採取装置(10)において、
前記血漿導入工程において、前記制御部(26)は、前記遠心分離器(120)から最初に流出した血漿を前記中間バッグ(126a)に移送する、
ことを特徴とする血液成分採取装置(10)。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013510930A JP5883436B2 (ja) | 2011-04-20 | 2012-04-02 | 血液成分採取装置 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011094075 | 2011-04-20 | ||
JP2011094075 | 2011-04-20 | ||
PCT/JP2012/058919 WO2012144312A1 (ja) | 2011-04-20 | 2012-04-02 | 血液成分採取装置 |
JP2013510930A JP5883436B2 (ja) | 2011-04-20 | 2012-04-02 | 血液成分採取装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2012144312A1 JPWO2012144312A1 (ja) | 2014-07-28 |
JP5883436B2 true JP5883436B2 (ja) | 2016-03-15 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013510930A Active JP5883436B2 (ja) | 2011-04-20 | 2012-04-02 | 血液成分採取装置 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP5883436B2 (ja) |
WO (1) | WO2012144312A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020166700A1 (ja) * | 2019-02-15 | 2020-08-20 | テルモ株式会社 | 血小板溶解物の製造方法、製造システム及びバッグセット |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005199055A (ja) * | 2003-12-16 | 2005-07-28 | Terumo Corp | 血液成分採取装置 |
JP2006204623A (ja) * | 2005-01-28 | 2006-08-10 | Terumo Corp | フィルター装置および血液成分採取装置 |
WO2007041716A1 (en) * | 2005-10-05 | 2007-04-12 | Gambro Bct, Inc. | Method and apparatus for leukoreduction of red blood cells |
US20090259163A1 (en) * | 2008-04-14 | 2009-10-15 | Etienne Pages | Three-Line Apheresis System and Method |
-
2012
- 2012-04-02 JP JP2013510930A patent/JP5883436B2/ja active Active
- 2012-04-02 WO PCT/JP2012/058919 patent/WO2012144312A1/ja active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005199055A (ja) * | 2003-12-16 | 2005-07-28 | Terumo Corp | 血液成分採取装置 |
JP2006204623A (ja) * | 2005-01-28 | 2006-08-10 | Terumo Corp | フィルター装置および血液成分採取装置 |
WO2007041716A1 (en) * | 2005-10-05 | 2007-04-12 | Gambro Bct, Inc. | Method and apparatus for leukoreduction of red blood cells |
US20090259163A1 (en) * | 2008-04-14 | 2009-10-15 | Etienne Pages | Three-Line Apheresis System and Method |
Also Published As
Publication number | Publication date |
---|---|
JPWO2012144312A1 (ja) | 2014-07-28 |
WO2012144312A1 (ja) | 2012-10-26 |
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