JP5839362B2 - ホルモン変動の症状を治療または予防するための方法および組成物 - Google Patents

ホルモン変動の症状を治療または予防するための方法および組成物 Download PDF

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JP5839362B2
JP5839362B2 JP2012556166A JP2012556166A JP5839362B2 JP 5839362 B2 JP5839362 B2 JP 5839362B2 JP 2012556166 A JP2012556166 A JP 2012556166A JP 2012556166 A JP2012556166 A JP 2012556166A JP 5839362 B2 JP5839362 B2 JP 5839362B2
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symptoms
pharmaceutical composition
dextromethorphan
hormonal
subject
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JP2013521297A5 (enExample
JP2013521297A (ja
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ロイスター,ジュニア,ジョージ,イー.
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FERVENT PHARMACEUTICALS LLC
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FERVENT PHARMACEUTICALS LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2012556166A 2010-03-02 2011-03-01 ホルモン変動の症状を治療または予防するための方法および組成物 Active JP5839362B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30963810P 2010-03-02 2010-03-02
US61/309,638 2010-03-02
PCT/US2011/026650 WO2011109367A2 (en) 2010-03-02 2011-03-01 Methods and compositions for treating or preventing symptoms of hormonal variations

Publications (3)

Publication Number Publication Date
JP2013521297A JP2013521297A (ja) 2013-06-10
JP2013521297A5 JP2013521297A5 (enExample) 2014-05-15
JP5839362B2 true JP5839362B2 (ja) 2016-01-06

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ID=44531862

Family Applications (1)

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JP2012556166A Active JP5839362B2 (ja) 2010-03-02 2011-03-01 ホルモン変動の症状を治療または予防するための方法および組成物

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Country Link
US (1) US20110218213A1 (enExample)
EP (1) EP2542241B1 (enExample)
JP (1) JP5839362B2 (enExample)
CN (1) CN102858343B (enExample)
AU (3) AU2011223807B2 (enExample)
BR (1) BR112012022052B1 (enExample)
CA (1) CA2828041C (enExample)
EA (1) EA027350B1 (enExample)
ES (1) ES2574210T3 (enExample)
IL (2) IL221706A (enExample)
PL (1) PL2542241T3 (enExample)
WO (1) WO2011109367A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9616123B1 (en) * 2012-03-05 2017-04-11 Robert L. Knobler Method and compound for treatment of menopausal symptoms
JP6038416B1 (ja) * 2015-04-07 2016-12-07 株式会社明治 火照り抑制剤
WO2019094596A1 (en) 2017-11-09 2019-05-16 The Trustees Of Columbia University In The City Of New York Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders
US11491120B2 (en) 2017-11-09 2022-11-08 The Trustees Of Columbia University In The City Of New York Pharmacological prophylactics against stress-induced affective disorders in females
EP3958862A4 (en) * 2019-04-22 2023-01-25 Robert L. Knobler NON-HORMONIC HOT FLASH TREATMENT
US20220401366A1 (en) * 2019-11-15 2022-12-22 Consegna Pharma, Inc. Long acting nmda antagonists

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
CA2115792C (en) * 1993-03-05 2005-11-01 David J. Mayer Method for the treatment of pain
EP2283821A1 (en) * 1993-11-19 2011-02-16 Alkermes, Inc. Preparation of biodegradable microparticles containing a biologically active agent
AUPN605795A0 (en) * 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
NZ517044A (en) * 1999-07-22 2004-02-27 Univ Rochester Gamma-aminobutyric acid analogues, e.g. gabapentin and pregabalin, to treat symptoms of hormonal variation, including hot flushes, nausea, emesis and fever
US20040002482A1 (en) * 2000-08-30 2004-01-01 Dudley Robert E. Androgen pharmaceutical composition and method for treating depression
US6569471B2 (en) * 2000-09-01 2003-05-27 Natumin Pharma Ab Method for the treatment of symptoms related to normal hormonal variations in women
US20050129783A1 (en) * 2001-04-19 2005-06-16 Mccleary Edward L. Composition and method for treatment of neurophysiological conditions and maintenance of neurophysiological health
WO2003037334A1 (en) * 2001-10-31 2003-05-08 Merck & Co., Inc. Method for treating or preventing symptoms of hormonal variation including hot flashes
EP1534258A2 (en) * 2002-08-15 2005-06-01 Wyeth AGONISM OF THE 5HT 2a RECEPTOR FOR TREATMENT OF THERMOREGULATORY DYSFUNCTION
HUP0303313A2 (hu) * 2003-10-09 2005-07-28 Richter Gedeon Vegyészeti Gyár Rt. Transzdermális gyógyszerkészítmények
US7855195B2 (en) * 2003-12-02 2010-12-21 Pharmaneuroboost N.V. Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
EP1753460A2 (en) * 2004-05-11 2007-02-21 Pfizer Products Inc. Combination of atypical antipsychotics and 5-ht1b receptor antagonists
CA2569411A1 (en) * 2004-06-04 2005-12-22 Mood Management Sciences, Llc Methods and compositions for treating mood disorder
EP1827450A4 (en) * 2004-11-17 2009-04-22 Cypress Bioscience Inc METHOD FOR REDUCING THE SIDE EFFECTS OF TREATMENT WITH MIRTAZAPINE
MX2008000248A (es) * 2005-07-06 2008-03-19 Sepracor Inc Combinaciones de eszopiclona y un antidepresivo y metodos de tratamiento contra la menopausia y trastornos del estado de animo, la ansiedad y trastornos cognitivos.
JP5528705B2 (ja) * 2005-12-13 2014-06-25 トリニティ ラボラトリーズ インコーポレイテッド ヒトにおける早漏を治療するための方法
JP2009525343A (ja) * 2006-02-03 2009-07-09 アバニール・ファーマシューティカルズ 鬱病、不安および神経変性疾患を治療するためのデキストロメトルファンおよびキニジンを含む薬剤組成物
US7645750B2 (en) * 2006-12-13 2010-01-12 Yung Shin Pharmaceutical Ind. Co., Ltd. Method of treating symptoms of hormonal variations
ES2423485T3 (es) * 2007-03-19 2013-09-20 Acadia Pharmaceuticals Inc. Asociaciones de agonistas y antagonistas inversos 5-HT2A con antipsicóticos
CN102223893B (zh) * 2008-07-22 2014-07-16 曼诺吉尼克斯公司 治疗与绝经、激素改变和关节炎相关的症状的组合物和方法

Also Published As

Publication number Publication date
ES2574210T3 (es) 2016-06-15
BR112012022052A2 (pt) 2020-07-07
WO2011109367A4 (en) 2012-02-23
AU2016213776B2 (en) 2018-04-12
IL253853B (en) 2019-05-30
CA2828041A1 (en) 2011-09-09
EA201290851A1 (ru) 2013-04-30
WO2011109367A3 (en) 2011-12-29
CN102858343B (zh) 2015-11-25
EP2542241A4 (en) 2013-11-06
AU2016213776A1 (en) 2016-09-01
AU2011223807B2 (en) 2016-05-12
AU2011223807A1 (en) 2012-10-18
IL221706A (en) 2017-08-31
CN102858343A (zh) 2013-01-02
WO2011109367A2 (en) 2011-09-09
EA027350B1 (ru) 2017-07-31
BR112012022052B1 (pt) 2021-06-29
EP2542241A2 (en) 2013-01-09
AU2018205147A1 (en) 2018-08-02
PL2542241T3 (pl) 2016-12-30
EP2542241B1 (en) 2016-04-27
IL253853A0 (en) 2017-09-28
JP2013521297A (ja) 2013-06-10
US20110218213A1 (en) 2011-09-08
CA2828041C (en) 2018-04-17

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