JP5820722B2 - シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用 - Google Patents
シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用 Download PDFInfo
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- JP5820722B2 JP5820722B2 JP2011512478A JP2011512478A JP5820722B2 JP 5820722 B2 JP5820722 B2 JP 5820722B2 JP 2011512478 A JP2011512478 A JP 2011512478A JP 2011512478 A JP2011512478 A JP 2011512478A JP 5820722 B2 JP5820722 B2 JP 5820722B2
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5964908P | 2008-06-06 | 2008-06-06 | |
| US61/059,649 | 2008-06-06 | ||
| PCT/US2009/003411 WO2010002428A2 (en) | 2008-06-06 | 2009-06-05 | Novel macrocyclic peptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011523952A JP2011523952A (ja) | 2011-08-25 |
| JP2011523952A5 JP2011523952A5 (OSRAM) | 2012-07-26 |
| JP5820722B2 true JP5820722B2 (ja) | 2015-11-24 |
Family
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Family Applications (1)
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| JP2011512478A Expired - Fee Related JP5820722B2 (ja) | 2008-06-06 | 2009-06-05 | シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9090671B2 (OSRAM) |
| EP (1) | EP2280989B1 (OSRAM) |
| JP (1) | JP5820722B2 (OSRAM) |
| CN (1) | CN102083852A (OSRAM) |
| CA (1) | CA2724523A1 (OSRAM) |
| WO (1) | WO2010002428A2 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2583494C (en) * | 2004-10-01 | 2014-01-21 | Scynexis, Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection |
| DE602006020152D1 (de) | 2005-09-30 | 2011-03-31 | Scynexis Inc | Arylalkyl- und heteroarylalkyl-derivate von cyclosporin a bei der behandlung und vorbeugung einer virusinfektion |
| CN101511357B (zh) | 2006-05-19 | 2011-11-02 | 西尼克斯公司 | 环孢菌素类化合物及其组合物在制备治疗和预防眼部疾病的药物中的应用 |
| EP2027761A1 (fr) * | 2006-06-02 | 2009-02-25 | Claude Annie Perrichon | Gestion des electrons actifs |
| US9090671B2 (en) | 2008-06-06 | 2015-07-28 | Scynexis, Inc. | Macrocyclic peptides |
| US20090306033A1 (en) * | 2008-06-06 | 2009-12-10 | Keqiang Li | Novel cyclic peptides |
| CA2748389A1 (en) | 2008-12-31 | 2010-07-08 | Scynexis, Inc. | Derivatives of cyclosporin a |
| WO2012103520A1 (en) | 2011-01-28 | 2012-08-02 | Board Of Regents Of The University Of Nebraska | Methods and compositions for modulating cyclophilin d |
| EP3263587A1 (en) | 2012-06-01 | 2018-01-03 | Allergan, Inc. | Cyclosporin a analogs |
| TW201639873A (zh) | 2015-01-08 | 2016-11-16 | 歐樂根公司 | Ｍｅｂｍｔ側鏈已環化之環孢菌素衍生物 |
| CN109485771A (zh) * | 2018-10-30 | 2019-03-19 | 焦作中维特品药业股份有限公司 | 一种交联聚维酮的制备方法 |
| JP7277222B2 (ja) | 2019-03-29 | 2023-05-18 | 出光興産株式会社 | 潤滑油組成物 |
| CA3152922A1 (en) * | 2019-10-12 | 2021-04-15 | Michael Peel | Treatment and prevention of nephrotoxin-induced kidney injuries |
| CN114230498B (zh) * | 2021-12-30 | 2023-11-17 | 湖北华世通生物医药科技有限公司 | β-(二甲氨基)乙基对甲苯磺酸巯酯盐酸盐的制备方法 |
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| US4798823A (en) * | 1987-06-03 | 1989-01-17 | Merck & Co., Inc. | New cyclosporin analogs with modified "C-9 amino acids" |
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| FR2757520B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent |
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| JP2013513595A (ja) | 2009-12-09 | 2013-04-22 | サイネクシス，インコーポレーテッド | 新規環状ペプチド |
-
2009
- 2009-06-05 US US12/479,633 patent/US9090671B2/en not_active Expired - Fee Related
- 2009-06-05 JP JP2011512478A patent/JP5820722B2/ja not_active Expired - Fee Related
- 2009-06-05 CN CN2009801261909A patent/CN102083852A/zh active Pending
- 2009-06-05 EP EP09773881.9A patent/EP2280989B1/en not_active Not-in-force
- 2009-06-05 WO PCT/US2009/003411 patent/WO2010002428A2/en not_active Ceased
- 2009-06-05 CA CA2724523A patent/CA2724523A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010002428A2 (en) | 2010-01-07 |
| CN102083852A (zh) | 2011-06-01 |
| JP2011523952A (ja) | 2011-08-25 |
| WO2010002428A3 (en) | 2010-03-11 |
| US9090671B2 (en) | 2015-07-28 |
| EP2280989A2 (en) | 2011-02-09 |
| CA2724523A1 (en) | 2010-01-07 |
| EP2280989B1 (en) | 2016-02-10 |
| US20090312300A1 (en) | 2009-12-17 |
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