JP5814119B2 - 健康的な老化および長寿を予測および促進するｆｏｘｏ３ａの多型およびハプロタイプを使用する方法 - Google Patents

健康的な老化および長寿を予測および促進するｆｏｘｏ３ａの多型およびハプロタイプを使用する方法 Download PDF

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JP5814119B2
JP5814119B2 JP2011523071A JP2011523071A JP5814119B2 JP 5814119 B2 JP5814119 B2 JP 5814119B2 JP 2011523071 A JP2011523071 A JP 2011523071A JP 2011523071 A JP2011523071 A JP 2011523071A JP 5814119 B2 JP5814119 B2 JP 5814119B2
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foxo3a
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エイチソン ドンロン ティモシー
エイチソン ドンロン ティモシー
ジョン ウィルコックス ブラッドリー
ジョン ウィルコックス ブラッドリー
ジェイ カーブ デイビット
ジェイ カーブ デイビット
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/125—Allele specific primer extension
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2011523071A 2008-08-10 2009-08-10 健康的な老化および長寿を予測および促進するｆｏｘｏ３ａの多型およびハプロタイプを使用する方法 Active JP5814119B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8772208P 2008-08-10 2008-08-10
US61/087,722 2008-08-10
PCT/US2009/053307 WO2010019519A2 (en) 2008-08-10 2009-08-10 Method of using foxo3a polymorphisms and haplotypes to predict and promote healthy aging and longevity

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JP2011530312A JP2011530312A (ja) 2011-12-22
JP2011530312A5 JP2011530312A5 (enExample) 2015-06-18
JP5814119B2 true JP5814119B2 (ja) 2015-11-17

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JP2011523071A Active JP5814119B2 (ja) 2008-08-10 2009-08-10 健康的な老化および長寿を予測および促進するｆｏｘｏ３ａの多型およびハプロタイプを使用する方法

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US (3) US20110212447A1 (enExample)
EP (1) EP2324127B1 (enExample)
JP (1) JP5814119B2 (enExample)
KR (2) KR20160102081A (enExample)
CN (1) CN102177255B (enExample)
AU (1) AU2009282172B2 (enExample)
CA (1) CA2733597C (enExample)
DK (1) DK2324127T3 (enExample)
WO (1) WO2010019519A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2324127B1 (en) * 2008-08-10 2015-01-21 Kuakini Medical Center Method of using foxo3a polymorphisms and haplotypes to predict and promote healthy aging and longevity
US8990135B2 (en) * 2010-06-15 2015-03-24 The Regents Of The University Of Michigan Personalized health risk assessment for critical care
CN103233001B (zh) * 2012-06-25 2016-11-02 西北农林科技大学 秦川牛FoxO1基因单核苷酸多态性分子标记的检测方法与应用
KR102017562B1 (ko) * 2013-03-13 2019-09-03 (주)아모레퍼시픽 미백 효능 물질의 스크리닝 방법
WO2017062751A1 (en) * 2015-10-08 2017-04-13 The Regents Of The University Of California Compounds and methods for promoting stress resistance
WO2018183353A1 (en) * 2017-03-27 2018-10-04 Cardax Pharma, Inc. Small molecule compounds to support healthy human aging
EP3622660B1 (en) * 2017-05-12 2023-08-30 Massachusetts Institute of Technology Systems and methods for crowdsourcing, analyzing, and/or matching personal data
WO2019156591A1 (en) * 2018-02-12 2019-08-15 Limited Liability Company "Gero" Methods and systems for prediction of frailty background
CN111235250A (zh) * 2020-03-31 2020-06-05 中国科学院昆明动物研究所 与健康老龄相关的关键通路及其外周血dna甲基化位点标志物和应用
CN115466321B (zh) * 2022-09-23 2024-03-22 南方医科大学珠江医院 FOXO3a-DRI肽段、其药物组合物及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7932049B2 (en) 2002-12-23 2011-04-26 University Of Massachusetts Methods of identifying longevity modulators and therapeutic methods of use thereof
US20070105109A1 (en) 2003-07-02 2007-05-10 Geesaman Bard J Sirt1 and genetic disorders
US20060069049A1 (en) 2003-12-29 2006-03-30 President And Fellows Of Harvard College Methods and reagents related to foxo
EP1774044A4 (en) * 2004-06-03 2009-06-10 Univ Johns Hopkins METHODS OF SCREENING FOR CELL PROLIFERATION OR NEOPLASTIC DISORDERS
US7622271B2 (en) * 2004-07-26 2009-11-24 University Of Washington Identification of aging genes through large-scale analysis
US20070118398A1 (en) * 2005-11-18 2007-05-24 Flicker Technologies, Llc System and method for estimating life expectancy and providing customized advice for improving life expectancy
JP5292569B2 (ja) * 2006-11-10 2013-09-18 国立大学法人名古屋大学 抗老化転写因子活性化剤及びその利用
EP2324127B1 (en) * 2008-08-10 2015-01-21 Kuakini Medical Center Method of using foxo3a polymorphisms and haplotypes to predict and promote healthy aging and longevity

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Publication number Publication date
WO2010019519A3 (en) 2010-05-27
EP2324127A2 (en) 2011-05-25
HK1158271A1 (en) 2012-07-13
AU2009282172B2 (en) 2016-06-02
WO2010019519A2 (en) 2010-02-18
CN102177255B (zh) 2015-12-16
KR20110057147A (ko) 2011-05-31
EP2324127B1 (en) 2015-01-21
US20150337383A1 (en) 2015-11-26
CA2733597C (en) 2019-02-26
US20110212447A1 (en) 2011-09-01
CA2733597A1 (en) 2010-02-18
CN102177255A (zh) 2011-09-07
DK2324127T3 (en) 2015-04-27
US20130295566A1 (en) 2013-11-07
JP2011530312A (ja) 2011-12-22
KR20160102081A (ko) 2016-08-26
EP2324127A4 (en) 2012-06-13
KR101649541B1 (ko) 2016-08-19
AU2009282172A1 (en) 2010-02-18

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