JP5808631B2 - 血管新生用足場、及び再生医療用の血管の製造方法 - Google Patents

血管新生用足場、及び再生医療用の血管の製造方法 Download PDF

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Publication number
JP5808631B2
JP5808631B2 JP2011215549A JP2011215549A JP5808631B2 JP 5808631 B2 JP5808631 B2 JP 5808631B2 JP 2011215549 A JP2011215549 A JP 2011215549A JP 2011215549 A JP2011215549 A JP 2011215549A JP 5808631 B2 JP5808631 B2 JP 5808631B2
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Prior art keywords
scaffold
vascular endothelial
angiogenesis
genetically modified
migration
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JP2011215549A
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Japanese (ja)
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JP2013074936A (ja
JP2013074936A5 (cg-RX-API-DMAC7.html
Inventor
玲子 岩澤
玲子 岩澤
中村　健太郎
中村　　健太郎
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Fujifilm Corp
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Fujifilm Corp
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Priority to JP2011215549A priority Critical patent/JP5808631B2/ja
Priority to US13/597,578 priority patent/US20130084638A1/en
Priority to EP12182347.0A priority patent/EP2578246B1/en
Publication of JP2013074936A publication Critical patent/JP2013074936A/ja
Publication of JP2013074936A5 publication Critical patent/JP2013074936A5/ja
Priority to US14/340,942 priority patent/US20140371145A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3808—Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2011215549A 2011-09-29 2011-09-29 血管新生用足場、及び再生医療用の血管の製造方法 Active JP5808631B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2011215549A JP5808631B2 (ja) 2011-09-29 2011-09-29 血管新生用足場、及び再生医療用の血管の製造方法
US13/597,578 US20130084638A1 (en) 2011-09-29 2012-08-29 Scaffold for vascular endothelial cell migration
EP12182347.0A EP2578246B1 (en) 2011-09-29 2012-08-30 Scaffold for vascular endothelial cell migration
US14/340,942 US20140371145A1 (en) 2011-09-29 2014-07-25 Scaffold for vascular endothelial cell migration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011215549A JP5808631B2 (ja) 2011-09-29 2011-09-29 血管新生用足場、及び再生医療用の血管の製造方法

Publications (3)

Publication Number Publication Date
JP2013074936A JP2013074936A (ja) 2013-04-25
JP2013074936A5 JP2013074936A5 (cg-RX-API-DMAC7.html) 2014-01-30
JP5808631B2 true JP5808631B2 (ja) 2015-11-10

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US (2) US20130084638A1 (cg-RX-API-DMAC7.html)
EP (1) EP2578246B1 (cg-RX-API-DMAC7.html)
JP (1) JP5808631B2 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5876787B2 (ja) * 2011-08-31 2016-03-02 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
JP6534269B2 (ja) * 2015-03-18 2019-06-26 富士フイルム株式会社 管状構造物、細胞構造体の製造方法、及び管状構造物の製造方法
CN107735405B (zh) * 2015-06-25 2022-04-08 克拉根制药株式会社 具有胶原模拟肽结构的聚合肽和凝胶
JPWO2017200039A1 (ja) * 2016-05-19 2019-03-22 富士フイルム株式会社 細胞培養方法、培地及び培地キット
JP6854904B2 (ja) * 2017-08-30 2021-04-07 富士フイルム株式会社 血管新生剤およびその製造方法
CN111032099B (zh) 2017-08-30 2022-08-30 富士胶片株式会社 细胞移植用设备及其制造方法
WO2019103981A1 (en) * 2017-11-22 2019-05-31 Geltor Inc. Methods and systems for engineering collagen
CN113444167B (zh) * 2021-07-15 2022-09-30 陕西巨子生物技术有限公司 重组人胶原蛋白多肽及其应用
WO2024029629A1 (ja) 2022-08-04 2024-02-08 三栄源エフ・エフ・アイ株式会社 細胞培養用の多孔質足場及びその製造方法
CN121100176A (zh) * 2023-05-15 2025-12-09 国立大学法人大阪大学 由生物体组织或器官制造高纯度血管内皮细胞群的方法

Family Cites Families (17)

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US6231881B1 (en) * 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
US6096710A (en) * 1995-11-17 2000-08-01 The Regents Of The University Of California Collagen-like peptoid residue-containing structures
EP1014176B1 (en) 1998-12-23 2009-04-29 FUJIFILM Manufacturing Europe B.V. Silver halide emulsions containing recombinant gelatin-like proteins
US6992172B1 (en) 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
CA2405291A1 (en) * 2000-04-06 2001-10-18 Wayne P. Franco Methods of using growth factors for treating heart disease
US7232802B2 (en) 2001-12-21 2007-06-19 Zimmer Orthobiologics, Inc. Compositions and methods for promoting myocardial and peripheral angiogenesis
US20040063206A1 (en) * 2002-09-30 2004-04-01 Rowley Jon A. Programmable scaffold and method for making and using the same
EP1875924B1 (en) 2003-03-28 2010-04-28 FUJIFILM Manufacturing Europe B.V. RGD-enriched gelatine-like proteins for prevention of platelet aggregation
US20050002904A1 (en) * 2003-07-03 2005-01-06 Wary Kishore K. Uses of vascular endothelial growth factor and type I collagen inducible protein (VCIP)
JP2006083095A (ja) 2004-09-16 2006-03-30 Tohoku Univ 幹細胞および／または内皮前駆細胞の分化促進剤
JP5548983B2 (ja) 2007-02-21 2014-07-16 富士フイルム株式会社 組換えゼラチン
WO2008133196A1 (ja) * 2007-04-19 2008-11-06 Fujifilm Corporation 再生医療用材料
WO2009072508A1 (ja) * 2007-12-03 2009-06-11 Fujifilm Corporation 体内埋め込み用の医療用組成物
EP2428215B1 (en) * 2009-05-07 2017-10-18 FUJIFILM Corporation Recombinant gelatin for use in the treatment of ischemic and heart disease and others
WO2010147109A1 (ja) 2009-06-15 2010-12-23 富士フイルム株式会社 遺伝子組み換えゼラチン及び塩基性線維芽細胞増殖因子を含む血管新生誘導剤
US9597432B2 (en) * 2010-03-01 2017-03-21 Fujifilm Corporation Cell construct comprising polymer blocks having biocompatibility and cells
EP2543398B1 (en) * 2010-03-02 2019-10-16 FUJIFILM Corporation Cell support and bone regeneration material

Also Published As

Publication number Publication date
US20140371145A1 (en) 2014-12-18
JP2013074936A (ja) 2013-04-25
EP2578246A2 (en) 2013-04-10
EP2578246A3 (en) 2015-01-14
US20130084638A1 (en) 2013-04-04
EP2578246B1 (en) 2016-06-01

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