JP5801197B2 - 痛みの治療に関する薬剤及び方法 - Google Patents

痛みの治療に関する薬剤及び方法 Download PDF

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JP5801197B2
JP5801197B2 JP2011525298A JP2011525298A JP5801197B2 JP 5801197 B2 JP5801197 B2 JP 5801197B2 JP 2011525298 A JP2011525298 A JP 2011525298A JP 2011525298 A JP2011525298 A JP 2011525298A JP 5801197 B2 JP5801197 B2 JP 5801197B2
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pain
tat
peptide
nr2b9c
seq
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JP2012501973A5 (enExample
JP2012501973A (ja
Inventor
マイケル ピー． ベルメアース
マイケル ピー． ベルメアース
ジェー． デービッド ガーマン
ジェー． デービッド ガーマン
ピーター エス． ルー
ピーター エス． ルー
マイケル ダブリュ． サルター
マイケル ダブリュ． サルター
マイケル ティミアンスキ
マイケル ティミアンスキ
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ノノ インコーポレイテッド
ノノ インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2011525298A 2008-09-03 2009-09-02 痛みの治療に関する薬剤及び方法 Expired - Fee Related JP5801197B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9402608P 2008-09-03 2008-09-03
US61/094,026 2008-09-03
PCT/US2009/055786 WO2010028089A2 (en) 2008-09-03 2009-09-02 Agents and methods for treatment of pain

Publications (3)

Publication Number Publication Date
JP2012501973A JP2012501973A (ja) 2012-01-26
JP2012501973A5 JP2012501973A5 (enExample) 2012-08-30
JP5801197B2 true JP5801197B2 (ja) 2015-10-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011525298A Expired - Fee Related JP5801197B2 (ja) 2008-09-03 2009-09-02 痛みの治療に関する薬剤及び方法

Country Status (7)

Country Link
US (3) US8324168B2 (enExample)
EP (1) EP2334315B1 (enExample)
JP (1) JP5801197B2 (enExample)
CN (1) CN102202677A (enExample)
AU (1) AU2009288088B2 (enExample)
CA (1) CA2739416C (enExample)
WO (1) WO2010028089A2 (enExample)

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CA2739416C (en) 2008-09-03 2017-10-31 Arbor Vita Corporation Agents and methods for treatment of pain
AU2011307488B2 (en) * 2010-10-01 2015-08-20 Hoba Therapeutics Aps Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain
US10414808B2 (en) 2012-05-18 2019-09-17 Janssen Biotech, Inc. Huwentoxin-IV variants and methods of use
AU2013262630B2 (en) * 2012-05-18 2017-11-16 Janssen Biotech, Inc. Huwentoxin-IV variants and methods of use
AU2013352437B2 (en) * 2012-11-28 2018-04-12 Nono Inc. Lyophilized formulation of TAT-NR2B9c
US10251935B2 (en) 2012-11-28 2019-04-09 Nono Inc. Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose
CN103012597B (zh) * 2012-12-31 2014-06-11 黑龙江大学 用于治疗骨质疏松症和止痛的OGP-CTx融合蛋白及编码该融合蛋白的核酸
KR20160064192A (ko) 2013-10-03 2016-06-07 얀센 바이오테크 인코포레이티드 프로톡신-ii 변이체 및 사용 방법
JP2017518738A (ja) * 2014-04-22 2017-07-13 キュー−ステート バイオサイエンシーズ， インコーポレイテッドＱ−Ｓｔａｔｅ Ｂｉｏｓｃｉｅｎｃｅｓ， Ｉｎｃ． 化合物の光遺伝学的分析
MA41642A (fr) 2015-03-03 2018-01-09 Janssen Biotech Inc Variants de protoxine ii et méthodes d'utilisation
US10048275B2 (en) 2015-03-13 2018-08-14 Q-State Biosciences, Inc. Cardiotoxicity screening methods
CN107921089A (zh) 2015-04-02 2018-04-17 詹森生物科技公司 原毒素‑ii变体及使用方法
EP3450446A4 (en) * 2016-04-27 2019-03-06 Biocells (Beijing) Biotech Co., Ltd. METHOD OF TREATING ADVERSE NEUROTOXICITY-RELATED INJURIES
CN107312071B (zh) * 2016-04-27 2018-11-06 拜西欧斯（北京）生物技术有限公司 兴奋性神经毒性相关损伤的治疗方法
CN107913395B (zh) * 2016-10-10 2019-12-13 拜西欧斯（北京）生物技术有限公司 神经兴奋性损伤相关多肽在预防、缓解或治疗疼痛的用途
US11767344B2 (en) 2017-07-05 2023-09-26 Biocells (Beijing) Biotech Co., Ltd. Pharmaceutically acceptable salts of polypeptides and methods of inhibiting the interaction between psd-95 and n-methyl-d-aspartic acid receptor (nmdar)
BR112020006321A2 (pt) 2017-09-30 2020-11-17 Biocells (Beijing) Biotech Co., Ltd. composição de peptídeos para tratamento de lesões relacionadas a neurotoxicidade excitatória
CN109265557B (zh) * 2018-09-18 2019-12-24 深圳瑞健生物科技有限公司 一种齐考诺肽和tat肽的融合多肽在制备药物中的应用
CN109106942B (zh) * 2018-09-18 2019-11-22 深圳瑞健生物科技有限公司 一种可通过血脑屏障的多肽在制备药物中的应用
CN109232745B (zh) * 2018-09-18 2020-02-28 深圳瑞健生物科技有限公司 一种可通过血脑屏障的多肽
CN109265558B (zh) * 2018-09-18 2019-12-24 深圳瑞健生物科技有限公司 改进型齐考诺肽在制备药物中的应用
CN118324862A (zh) * 2018-12-26 2024-07-12 思亲美有限公司 乙酰胆碱受体抑制肽及其用途
CN111097037A (zh) * 2020-01-16 2020-05-05 刘成龙 一种psd95-pdz1/2结构域抑制剂及其应用
CN120958011A (zh) * 2023-03-31 2025-11-14 青岛普美圣医药科技有限公司 具有延长的半衰期和提高的稳定性的多肽活性分子

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AU2009246316B2 (en) * 2008-05-16 2014-06-19 Nono Inc. Treatment for epilepsy
CA2739416C (en) 2008-09-03 2017-10-31 Arbor Vita Corporation Agents and methods for treatment of pain
JP5848712B2 (ja) * 2009-12-11 2016-01-27 ノノ インコーポレイテッド 虚血性疾患および他の疾患を治療するための薬剤および方法

Also Published As

Publication number Publication date
US8748387B2 (en) 2014-06-10
CA2739416A1 (en) 2010-03-11
AU2009288088A1 (en) 2010-03-11
CA2739416C (en) 2017-10-31
US8324168B2 (en) 2012-12-04
EP2334315A2 (en) 2011-06-22
WO2010028089A2 (en) 2010-03-11
US20100062985A1 (en) 2010-03-11
US9365620B2 (en) 2016-06-14
EP2334315A4 (en) 2012-08-15
US20150018283A1 (en) 2015-01-15
US20130137641A1 (en) 2013-05-30
WO2010028089A3 (en) 2010-04-29
AU2009288088B2 (en) 2014-12-04
JP2012501973A (ja) 2012-01-26
EP2334315B1 (en) 2023-01-18
CN102202677A (zh) 2011-09-28

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