JP2012501973A5 - - Google Patents
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- Publication number
- JP2012501973A5 JP2012501973A5 JP2011525298A JP2011525298A JP2012501973A5 JP 2012501973 A5 JP2012501973 A5 JP 2012501973A5 JP 2011525298 A JP2011525298 A JP 2011525298A JP 2011525298 A JP2011525298 A JP 2011525298A JP 2012501973 A5 JP2012501973 A5 JP 2012501973A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- peptide
- composition according
- mimic
- pain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9402608P | 2008-09-03 | 2008-09-03 | |
| US61/094,026 | 2008-09-03 | ||
| PCT/US2009/055786 WO2010028089A2 (en) | 2008-09-03 | 2009-09-02 | Agents and methods for treatment of pain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012501973A JP2012501973A (ja) | 2012-01-26 |
| JP2012501973A5 true JP2012501973A5 (enExample) | 2012-08-30 |
| JP5801197B2 JP5801197B2 (ja) | 2015-10-28 |
Family
ID=41797838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011525298A Expired - Fee Related JP5801197B2 (ja) | 2008-09-03 | 2009-09-02 | 痛みの治療に関する薬剤及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8324168B2 (enExample) |
| EP (1) | EP2334315B1 (enExample) |
| JP (1) | JP5801197B2 (enExample) |
| CN (1) | CN102202677A (enExample) |
| AU (1) | AU2009288088B2 (enExample) |
| CA (1) | CA2739416C (enExample) |
| WO (1) | WO2010028089A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6005357B2 (ja) * | 2008-05-16 | 2016-10-12 | ノノ インコーポレイテッド | てんかんの治療 |
| EP2334315B1 (en) | 2008-09-03 | 2023-01-18 | NoNO Inc. | Agents and methods for treatment of pain |
| AU2011307488B2 (en) * | 2010-10-01 | 2015-08-20 | Hoba Therapeutics Aps | Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain |
| US10414808B2 (en) | 2012-05-18 | 2019-09-17 | Janssen Biotech, Inc. | Huwentoxin-IV variants and methods of use |
| CA2873860A1 (en) * | 2012-05-18 | 2013-11-21 | Janssen Biotech, Inc. | Huwentoxin-iv variants and methods of use |
| JP6427104B2 (ja) * | 2012-11-28 | 2018-11-21 | ノノ インコーポレイテッド | Ｔａｔ−ＮＲ２Ｂ９ｃの凍結乾燥製剤 |
| US10251935B2 (en) | 2012-11-28 | 2019-04-09 | Nono Inc. | Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose |
| CN103012597B (zh) * | 2012-12-31 | 2014-06-11 | 黑龙江大学 | 用于治疗骨质疏松症和止痛的OGP-CTx融合蛋白及编码该融合蛋白的核酸 |
| ES2841173T3 (es) | 2013-10-03 | 2021-07-07 | Janssen Biotech Inc | Variantes de Protoxina-II y métodos de uso |
| JP2017521044A (ja) | 2014-04-22 | 2017-08-03 | キュー−ステート バイオサイエンシーズ， インコーポレイテッドＱ−Ｓｔａｔｅ Ｂｉｏｓｃｉｅｎｃｅｓ， Ｉｎｃ． | 疼痛及び感覚障害のための化合物の分析 |
| MA41642A (fr) | 2015-03-03 | 2018-01-09 | Janssen Biotech Inc | Variants de protoxine ii et méthodes d'utilisation |
| US10048275B2 (en) | 2015-03-13 | 2018-08-14 | Q-State Biosciences, Inc. | Cardiotoxicity screening methods |
| JP6985151B2 (ja) | 2015-04-02 | 2021-12-22 | ヤンセン バイオテツク，インコーポレーテツド | プロトキシン−ｉｉ変異体及びその使用方法 |
| CN107312071B (zh) * | 2016-04-27 | 2018-11-06 | 拜西欧斯（北京）生物技术有限公司 | 兴奋性神经毒性相关损伤的治疗方法 |
| US20190134150A1 (en) * | 2016-04-27 | 2019-05-09 | Biocells (Beijing) Biotech Co., Ltd. | Therapeutic methods for excitatory neurotoxicity-related injuries |
| CN107913395B (zh) * | 2016-10-10 | 2019-12-13 | 拜西欧斯（北京）生物技术有限公司 | 神经兴奋性损伤相关多肽在预防、缓解或治疗疼痛的用途 |
| BR112020000115A2 (pt) | 2017-07-05 | 2020-07-07 | Biocells (Beijing) Biotech Co., Ltd. | sais farmaceuticamente aceitáveis de polipeptídeos e uso dos mesmos |
| JP7073486B2 (ja) * | 2017-09-30 | 2022-05-23 | ▲拝▼西欧斯（北京）生物技▲術▼有限公司 | 興奮性神経毒性に関連した損傷の治療用ペプチド組成物 |
| CN109232745B (zh) * | 2018-09-18 | 2020-02-28 | 深圳瑞健生物科技有限公司 | 一种可通过血脑屏障的多肽 |
| CN109265558B (zh) * | 2018-09-18 | 2019-12-24 | 深圳瑞健生物科技有限公司 | 改进型齐考诺肽在制备药物中的应用 |
| CN109106942B (zh) * | 2018-09-18 | 2019-11-22 | 深圳瑞健生物科技有限公司 | 一种可通过血脑屏障的多肽在制备药物中的应用 |
| CN109265557B (zh) * | 2018-09-18 | 2019-12-24 | 深圳瑞健生物科技有限公司 | 一种齐考诺肽和tat肽的融合多肽在制备药物中的应用 |
| EP4393504A2 (en) * | 2018-12-26 | 2024-07-03 | Skinmed Co., Ltd. | Acetylcholine receptor inhibitory peptides and uses thereof |
| CN111097037A (zh) * | 2020-01-16 | 2020-05-05 | 刘成龙 | 一种psd95-pdz1/2结构域抑制剂及其应用 |
| WO2024199436A1 (zh) * | 2023-03-31 | 2024-10-03 | 青岛普美圣医药科技有限公司 | 具有延长的半衰期和提高的稳定性的多肽活性分子 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7760905B2 (en) | 1999-06-29 | 2010-07-20 | Digimarc Corporation | Wireless mobile phone with content processing |
| US7510824B2 (en) * | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| US7595297B2 (en) * | 1999-06-02 | 2009-09-29 | Michael Tymianski | Method of reducing injury to mammalian cells |
| US6759520B1 (en) | 1999-10-28 | 2004-07-06 | The New England Medical Center Hospitals, Inc. | Chimeric analgesic peptides |
| US20080119412A1 (en) * | 2003-12-23 | 2008-05-22 | Nono Inc. | Polypeptides for Modulating Binding of Trp Channel Proteins and Trp- Associated Proteins |
| US8003609B2 (en) * | 2004-03-30 | 2011-08-23 | The Hospital For Sick Children | Method for ameliorating pain by modification of NMDA receptors through inhibition of Src |
| US20080227684A1 (en) * | 2005-12-30 | 2008-09-18 | Belmares Michael P | Small Molecule Inhibitors of PDZ Interactions |
| US8633160B2 (en) * | 2005-12-30 | 2014-01-21 | Nono Inc. | Small molecule inhibitors of PDZ interactions |
| GB0610868D0 (en) | 2006-06-01 | 2006-07-12 | Syntaxin Ltd | Treatment of pain |
| US20100093829A1 (en) * | 2006-07-07 | 2010-04-15 | Gorman James R | Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures |
| EP1884521A1 (en) * | 2006-07-31 | 2008-02-06 | Xigen S.A. | Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins |
| US20080124698A1 (en) | 2006-11-28 | 2008-05-29 | Ebensberger Jason M | Virtual coatings application system with structured training and remote instructor capabilities |
| JP2010514781A (ja) * | 2006-12-29 | 2010-05-06 | ルバンス セラピュティックス インク． | Ｈｉｖ−ｔａｔに由来するポリペプチド断片を用いて安定化されるボツリヌス毒素を局所適用及び経皮送達する組成物及び方法 |
| JP5631595B2 (ja) * | 2007-03-02 | 2014-11-26 | ノノ インコーポレイテッド | Ｎ型カルシウムチャネルを阻害せずに卒中および他の疾患を治療する方法 |
| US20090062178A1 (en) * | 2007-04-06 | 2009-03-05 | Harrison Stephen D | Methods of use of gamma inhibitor compounds for the attenuation of pain |
| US20100204100A1 (en) * | 2007-04-19 | 2010-08-12 | The Johns Hopkins Univeristy | Biological agents active in central nervous system |
| US8008253B2 (en) * | 2007-07-03 | 2011-08-30 | Andrew Tasker | Treatment for anxiety |
| US8080518B2 (en) * | 2007-12-05 | 2011-12-20 | Arbor Vita Corporation | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| JP6005357B2 (ja) * | 2008-05-16 | 2016-10-12 | ノノ インコーポレイテッド | てんかんの治療 |
| EP2334315B1 (en) | 2008-09-03 | 2023-01-18 | NoNO Inc. | Agents and methods for treatment of pain |
| AU2010327936B2 (en) * | 2009-12-11 | 2015-08-20 | Nono Inc. | Agents and methods for treating ischemic and other diseases |
-
2009
- 2009-09-02 EP EP09812187.4A patent/EP2334315B1/en active Active
- 2009-09-02 WO PCT/US2009/055786 patent/WO2010028089A2/en not_active Ceased
- 2009-09-02 CA CA2739416A patent/CA2739416C/en active Active
- 2009-09-02 JP JP2011525298A patent/JP5801197B2/ja not_active Expired - Fee Related
- 2009-09-02 CN CN2009801431948A patent/CN102202677A/zh active Pending
- 2009-09-02 AU AU2009288088A patent/AU2009288088B2/en not_active Ceased
- 2009-09-03 US US12/553,096 patent/US8324168B2/en not_active Expired - Fee Related
-
2012
- 2012-11-13 US US13/675,893 patent/US8748387B2/en active Active
-
2014
- 2014-05-09 US US14/274,355 patent/US9365620B2/en not_active Expired - Fee Related
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