JP5785177B2 - ポリペプチドのネイティブライゲーション法 - Google Patents

ポリペプチドのネイティブライゲーション法 Download PDF

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Publication number
JP5785177B2
JP5785177B2 JP2012536000A JP2012536000A JP5785177B2 JP 5785177 B2 JP5785177 B2 JP 5785177B2 JP 2012536000 A JP2012536000 A JP 2012536000A JP 2012536000 A JP2012536000 A JP 2012536000A JP 5785177 B2 JP5785177 B2 JP 5785177B2
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polypeptide
formula
amino acid
ligation reaction
trt
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Japanese (ja)
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JP2013509396A5 (https=
JP2013509396A (ja
Inventor
ミディア レダ
ミディア レダ
デュール ジュリアン
デュール ジュリアン
オリビエ ナタリー
オリビエ ナタリー
メルニク オル
メルニク オル
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Institut Pasteur de Lille
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Institut Pasteur de Lille
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012536000A 2009-10-29 2010-10-28 ポリペプチドのネイティブライゲーション法 Active JP5785177B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0957639A FR2952058B1 (fr) 2009-10-29 2009-10-29 Procede de ligation native de polypeptides
FR0957639 2009-10-29
PCT/IB2010/054897 WO2011051906A1 (fr) 2009-10-29 2010-10-28 Procede de ligation native de polypeptides

Publications (3)

Publication Number Publication Date
JP2013509396A JP2013509396A (ja) 2013-03-14
JP2013509396A5 JP2013509396A5 (https=) 2013-12-19
JP5785177B2 true JP5785177B2 (ja) 2015-09-24

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ID=42145118

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JP2012536000A Active JP5785177B2 (ja) 2009-10-29 2010-10-28 ポリペプチドのネイティブライゲーション法

Country Status (9)

Country Link
US (1) US9029503B2 (https=)
EP (1) EP2493909B1 (https=)
JP (1) JP5785177B2 (https=)
CN (1) CN102770437B (https=)
CA (1) CA2778875C (https=)
DK (1) DK2493909T3 (https=)
ES (1) ES2493917T3 (https=)
FR (1) FR2952058B1 (https=)
WO (1) WO2011051906A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012005691A1 (en) * 2010-07-06 2012-01-12 Nanyang Technological University Compound for use in peptide synthesis
FR2971509B1 (fr) * 2011-02-16 2013-02-22 Centre Nat Rech Scient Procede de preparation de peptides par assemblage de multiples fragments peptidiques
FR2981352B1 (fr) * 2011-10-17 2015-07-03 Centre Nat Rech Scient Procede de synthese de proteines
FR2988392B1 (fr) * 2012-03-21 2014-04-11 Centre Nat Rech Scient Procede de ligation native

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI0832096T1 (en) * 1995-05-04 2001-12-31 Scripps Research Inst Synthesis of proteins by native chemical ligation
TR200901109T1 (tr) 1995-09-01 2012-02-21 Corixa Corporation Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler
WO1998028434A1 (en) * 1996-12-24 1998-07-02 The Scripps Research Institute General chemical ligation
US6570040B2 (en) 2000-03-16 2003-05-27 The Regents Of The University Of California Chemoselective ligation
DE60110127T2 (de) 2000-05-12 2006-02-02 Wisconsin Alumni Research Foundation, Madison Ligationsverfahren und reagenzien zur bildung einer amid-bindung
BR0113579A (pt) * 2000-09-08 2003-06-17 Gryphon Therapeutics Inc Proteìnas sintéticas modificadas por polìmero
CA2477159A1 (en) * 2002-02-20 2003-08-28 Invitrogen Corporation Highly homogeneous molecular markers for electrophoresis
US7667076B2 (en) 2005-09-14 2010-02-23 Regents Of The University Of California Amide forming chemical ligation

Also Published As

Publication number Publication date
EP2493909A1 (fr) 2012-09-05
FR2952058A1 (fr) 2011-05-06
CN102770437A (zh) 2012-11-07
JP2013509396A (ja) 2013-03-14
WO2011051906A1 (fr) 2011-05-05
ES2493917T3 (es) 2014-09-12
FR2952058B1 (fr) 2013-10-04
US20120220721A1 (en) 2012-08-30
US9029503B2 (en) 2015-05-12
CN102770437B (zh) 2016-04-20
CA2778875A1 (fr) 2011-05-05
CA2778875C (fr) 2017-11-07
EP2493909B1 (fr) 2014-05-21
DK2493909T3 (da) 2014-08-25

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