JP5783720B2 - 植物での糖タンパク質生成の改変 - Google Patents

植物での糖タンパク質生成の改変 Download PDF

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JP5783720B2
JP5783720B2 JP2010511461A JP2010511461A JP5783720B2 JP 5783720 B2 JP5783720 B2 JP 5783720B2 JP 2010511461 A JP2010511461 A JP 2010511461A JP 2010511461 A JP2010511461 A JP 2010511461A JP 5783720 B2 JP5783720 B2 JP 5783720B2
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protein
plant
nucleotide sequence
interest
seq
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JP2010531136A (ja
JP2010531136A5 (cg-RX-API-DMAC7.html
Inventor
マルク アンドレ ダオース
マルク アンドレ ダオース
ルイ フィリップ ヴェジナ
ルイ フィリップ ヴェジナ
ステファニー アーキン
ステファニー アーキン
ブルーアン エステル マルケ
ブルーアン エステル マルケ
ミュリエル バルドール
ミュリエル バルドール
カロル ビュレル
カロル ビュレル
ロイク ファイユ
ロイク ファイユ
パトリス ルルージュ
パトリス ルルージュ
ヴェロニク ゴモル
ヴェロニク ゴモル
クリストフ リフーエイ
クリストフ リフーエイ
トーマス パカレ
トーマス パカレ
クリストフ スルイユ
クリストフ スルイユ
Original Assignee
メディカゴ インコーポレイテッド
メディカゴ インコーポレイテッド
センター ナショナル ド ラ ルシェルシュ サイエンティフィーク
センター ナショナル ド ラ ルシェルシュ サイエンティフィーク
ユニヴェルシテ ド ルーアン
ユニヴェルシテ ド ルーアン
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

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  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Cultivation Of Plants (AREA)
JP2010511461A 2007-06-15 2008-06-13 植物での糖タンパク質生成の改変 Expired - Fee Related JP5783720B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94434407P 2007-06-15 2007-06-15
US60/944,344 2007-06-15
PCT/CA2008/001139 WO2008151440A1 (en) 2007-06-15 2008-06-13 Modifying glycoprotein production in plants

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JP2010531136A JP2010531136A (ja) 2010-09-24
JP2010531136A5 JP2010531136A5 (cg-RX-API-DMAC7.html) 2011-07-28
JP5783720B2 true JP5783720B2 (ja) 2015-09-24

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US (1) US20110008837A1 (cg-RX-API-DMAC7.html)
EP (1) EP2155880B1 (cg-RX-API-DMAC7.html)
JP (1) JP5783720B2 (cg-RX-API-DMAC7.html)
KR (2) KR20130075787A (cg-RX-API-DMAC7.html)
CN (3) CN103382487A (cg-RX-API-DMAC7.html)
AU (1) AU2008261527C1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0812538B1 (cg-RX-API-DMAC7.html)
CA (2) CA2700180C (cg-RX-API-DMAC7.html)
DK (1) DK2155880T3 (cg-RX-API-DMAC7.html)
EG (1) EG26600A (cg-RX-API-DMAC7.html)
ES (1) ES2624776T3 (cg-RX-API-DMAC7.html)
HU (1) HUE031698T2 (cg-RX-API-DMAC7.html)
IL (1) IL202568A (cg-RX-API-DMAC7.html)
MA (1) MA31516B1 (cg-RX-API-DMAC7.html)
MX (1) MX2009013665A (cg-RX-API-DMAC7.html)
NZ (2) NZ598417A (cg-RX-API-DMAC7.html)
PL (1) PL2155880T3 (cg-RX-API-DMAC7.html)
PT (1) PT2155880T (cg-RX-API-DMAC7.html)
RU (2) RU2499053C2 (cg-RX-API-DMAC7.html)
SG (1) SG185249A1 (cg-RX-API-DMAC7.html)
SI (1) SI2155880T1 (cg-RX-API-DMAC7.html)
TN (1) TN2009000512A1 (cg-RX-API-DMAC7.html)
WO (1) WO2008151440A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201000207B (cg-RX-API-DMAC7.html)

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CN102089432A (zh) 2008-07-08 2011-06-08 麦迪卡格公司 可溶性重组流感抗原
AU2009270404B2 (en) 2008-07-18 2015-01-29 Medicago Inc. New influenza virus immunizing epitope
HRP20180706T1 (hr) 2009-06-24 2018-06-01 Medicago Inc. Kimerna gripa nalik čestici koja sadrži hemaglutinin
JP5551780B2 (ja) 2009-09-22 2014-07-16 メディカゴ インコーポレイテッド 植物由来のタンパク質を調製する方法
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
US11673926B2 (en) * 2011-06-07 2023-06-13 Ibio, Inc. In vivo de-glycosylation of recombinant proteins by co-expression with PNGase F
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RU2731295C2 (ru) 2014-07-11 2020-09-01 Медикаго Инк. Модификация продуцирования белков в растениях
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NZ581944A (en) 2012-03-30
MX2009013665A (es) 2010-06-02
RU2013137208A (ru) 2015-02-20
WO2008151440A4 (en) 2009-02-26
RU2499053C2 (ru) 2013-11-20
AU2008261527B2 (en) 2014-04-10
KR20130075787A (ko) 2013-07-05
JP2010531136A (ja) 2010-09-24
CA2795379A1 (en) 2008-12-18
EP2155880A1 (en) 2010-02-24
TN2009000512A1 (en) 2011-03-31
AU2008261527B8 (en) 2014-04-24
EP2155880A4 (en) 2010-08-04
AU2008261527A1 (en) 2008-12-18
EP2155880B1 (en) 2016-08-10
DK2155880T3 (en) 2016-12-05
SG185249A1 (en) 2012-11-29
BRPI0812538B1 (pt) 2021-03-16
MA31516B1 (fr) 2010-07-01
RU2010101024A (ru) 2011-07-20
BRPI0812538A2 (pt) 2014-09-30
PT2155880T (pt) 2016-11-18
ES2624776T3 (es) 2017-07-17
CA2700180A1 (en) 2008-12-18
KR101385050B1 (ko) 2014-05-13
IL202568A0 (en) 2011-08-01
WO2008151440A8 (en) 2010-03-04
ZA201000207B (en) 2013-09-25
KR20100037602A (ko) 2010-04-09
US20110008837A1 (en) 2011-01-13
PL2155880T3 (pl) 2017-06-30
CN103382487A (zh) 2013-11-06
IL202568A (en) 2015-02-26
CN104962579A (zh) 2015-10-07
AU2008261527A8 (en) 2010-01-21
CA2700180C (en) 2013-01-29
EG26600A (en) 2014-03-23
HUE031698T2 (en) 2017-07-28
AU2008261527C1 (en) 2014-09-04
CN101918559A (zh) 2010-12-15
WO2008151440A1 (en) 2008-12-18
NZ598417A (en) 2013-06-28
SI2155880T1 (sl) 2017-03-31

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