SI2155880T1 - Modificiranje proizvodnje glikoproteina pri rastlinah - Google Patents

Modificiranje proizvodnje glikoproteina pri rastlinah

Info

Publication number
SI2155880T1
SI2155880T1 SI200831699A SI200831699A SI2155880T1 SI 2155880 T1 SI2155880 T1 SI 2155880T1 SI 200831699 A SI200831699 A SI 200831699A SI 200831699 A SI200831699 A SI 200831699A SI 2155880 T1 SI2155880 T1 SI 2155880T1
Authority
SI
Slovenia
Prior art keywords
plants
glycoprotein production
modifying glycoprotein
modifying
production
Prior art date
Application number
SI200831699A
Other languages
English (en)
Slovenian (sl)
Inventor
Marc-Andre D'aoust
Estelle Marquet-Blouin
Muriel Bardor
Carole Burel
Loic Faye
Patrice Lerouge
Louis-Philippe Vezina
Veronique Gomord
Stephanie Aquin
Christophe Rihouey
Thomas Paccalet
Christophe Sourrouille
Original Assignee
Medicago Inc.
Centre National De La Recherche Scientifique
Universite De Rouen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicago Inc., Centre National De La Recherche Scientifique, Universite De Rouen filed Critical Medicago Inc.
Publication of SI2155880T1 publication Critical patent/SI2155880T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Cultivation Of Plants (AREA)
SI200831699A 2007-06-15 2008-06-13 Modificiranje proizvodnje glikoproteina pri rastlinah SI2155880T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94434407P 2007-06-15 2007-06-15
EP08772802.8A EP2155880B1 (en) 2007-06-15 2008-06-13 Modifying glycoprotein production in plants
PCT/CA2008/001139 WO2008151440A1 (en) 2007-06-15 2008-06-13 Modifying glycoprotein production in plants

Publications (1)

Publication Number Publication Date
SI2155880T1 true SI2155880T1 (sl) 2017-03-31

Family

ID=40129187

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831699A SI2155880T1 (sl) 2007-06-15 2008-06-13 Modificiranje proizvodnje glikoproteina pri rastlinah

Country Status (24)

Country Link
US (1) US20110008837A1 (cg-RX-API-DMAC7.html)
EP (1) EP2155880B1 (cg-RX-API-DMAC7.html)
JP (1) JP5783720B2 (cg-RX-API-DMAC7.html)
KR (2) KR20130075787A (cg-RX-API-DMAC7.html)
CN (3) CN103382487A (cg-RX-API-DMAC7.html)
AU (1) AU2008261527C1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0812538B1 (cg-RX-API-DMAC7.html)
CA (2) CA2700180C (cg-RX-API-DMAC7.html)
DK (1) DK2155880T3 (cg-RX-API-DMAC7.html)
EG (1) EG26600A (cg-RX-API-DMAC7.html)
ES (1) ES2624776T3 (cg-RX-API-DMAC7.html)
HU (1) HUE031698T2 (cg-RX-API-DMAC7.html)
IL (1) IL202568A (cg-RX-API-DMAC7.html)
MA (1) MA31516B1 (cg-RX-API-DMAC7.html)
MX (1) MX2009013665A (cg-RX-API-DMAC7.html)
NZ (2) NZ598417A (cg-RX-API-DMAC7.html)
PL (1) PL2155880T3 (cg-RX-API-DMAC7.html)
PT (1) PT2155880T (cg-RX-API-DMAC7.html)
RU (2) RU2499053C2 (cg-RX-API-DMAC7.html)
SG (1) SG185249A1 (cg-RX-API-DMAC7.html)
SI (1) SI2155880T1 (cg-RX-API-DMAC7.html)
TN (1) TN2009000512A1 (cg-RX-API-DMAC7.html)
WO (1) WO2008151440A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201000207B (cg-RX-API-DMAC7.html)

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CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
KR20100120157A (ko) 2007-11-27 2010-11-12 메디카고 인코포레이티드 헤마글루티닌을 발현하는 트랜스제닉 식물에서 생산된 재조합 인플루엔자 바이러스-유사 입자(ＶＬＰｓ)
CN102089432A (zh) 2008-07-08 2011-06-08 麦迪卡格公司 可溶性重组流感抗原
AU2009270404B2 (en) 2008-07-18 2015-01-29 Medicago Inc. New influenza virus immunizing epitope
HRP20180706T1 (hr) 2009-06-24 2018-06-01 Medicago Inc. Kimerna gripa nalik čestici koja sadrži hemaglutinin
JP5551780B2 (ja) 2009-09-22 2014-07-16 メディカゴ インコーポレイテッド 植物由来のタンパク質を調製する方法
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
US11673926B2 (en) * 2011-06-07 2023-06-13 Ibio, Inc. In vivo de-glycosylation of recombinant proteins by co-expression with PNGase F
US9181532B2 (en) 2011-07-29 2015-11-10 Icon Genetics Gmbh Production of galactosylated N-glycans in plants
WO2013044390A1 (en) 2011-09-30 2013-04-04 Medicago Inc. Increasing virus-like particle yield in plants
KR20130125337A (ko) * 2012-05-08 2013-11-18 경상대학교산학협력단 고-만노오스형 n-글라이칸을 생산하는 식물체 및 이를 이용한 고-만노오스형 n-글라이칸의 생산방법
EP2978848B1 (en) 2013-03-28 2020-05-06 Medicago Inc. Influenza virus-like particle production in plants
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
RU2731295C2 (ru) 2014-07-11 2020-09-01 Медикаго Инк. Модификация продуцирования белков в растениях
EP3221455B1 (en) 2014-11-20 2020-08-12 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Compositions and methods for producing polypeptides with a modified glycosylation pattern in plant cells
EP3548612A4 (en) 2016-12-01 2020-04-15 Plantform Corporation TRANSGENIC PLANT WITH REDUCED FUCOSYL TRANSFERASE AND XYLOSYL TRANSFERASE ACTIVITY
US11649465B2 (en) * 2017-09-11 2023-05-16 R.J. Reynolds Tobacco Company Methods and compositions for increasing expression of genes of interest in a plant by co-expression with p21
EP4265104A4 (en) * 2021-01-15 2024-12-11 Denka Company Limited METHOD FOR DETERMINING CULTURE CONDITIONS, AND METHOD FOR PRODUCING DESIRED PROTEIN OR DESIRED PEPTIDE

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IL143641A0 (en) * 1998-12-09 2002-04-21 A method for manufacturing glycoproteins having human-type glycosylation
DE60024658T2 (de) * 1999-10-04 2006-08-24 Medicago Inc., Sainte Foy Promotor zur regulierung von fremdgenexpression
US7125978B1 (en) * 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
BR0014945A (pt) * 1999-10-21 2004-08-31 Monsanto Co Modificação pós-traducional de proteìnas recombinantes produzidas em plantas
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CN1761746B (zh) * 2003-01-22 2016-03-23 罗氏格黎卡特股份公司 融合构建体及其用来生产Fc受体结合亲和性和效应子功能提高的抗体的用途
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Also Published As

Publication number Publication date
NZ581944A (en) 2012-03-30
MX2009013665A (es) 2010-06-02
RU2013137208A (ru) 2015-02-20
WO2008151440A4 (en) 2009-02-26
RU2499053C2 (ru) 2013-11-20
AU2008261527B2 (en) 2014-04-10
KR20130075787A (ko) 2013-07-05
JP2010531136A (ja) 2010-09-24
CA2795379A1 (en) 2008-12-18
EP2155880A1 (en) 2010-02-24
TN2009000512A1 (en) 2011-03-31
AU2008261527B8 (en) 2014-04-24
EP2155880A4 (en) 2010-08-04
AU2008261527A1 (en) 2008-12-18
EP2155880B1 (en) 2016-08-10
DK2155880T3 (en) 2016-12-05
SG185249A1 (en) 2012-11-29
BRPI0812538B1 (pt) 2021-03-16
MA31516B1 (fr) 2010-07-01
RU2010101024A (ru) 2011-07-20
BRPI0812538A2 (pt) 2014-09-30
PT2155880T (pt) 2016-11-18
ES2624776T3 (es) 2017-07-17
CA2700180A1 (en) 2008-12-18
KR101385050B1 (ko) 2014-05-13
IL202568A0 (en) 2011-08-01
WO2008151440A8 (en) 2010-03-04
ZA201000207B (en) 2013-09-25
KR20100037602A (ko) 2010-04-09
US20110008837A1 (en) 2011-01-13
PL2155880T3 (pl) 2017-06-30
CN103382487A (zh) 2013-11-06
IL202568A (en) 2015-02-26
CN104962579A (zh) 2015-10-07
AU2008261527A8 (en) 2010-01-21
CA2700180C (en) 2013-01-29
EG26600A (en) 2014-03-23
HUE031698T2 (en) 2017-07-28
JP5783720B2 (ja) 2015-09-24
AU2008261527C1 (en) 2014-09-04
CN101918559A (zh) 2010-12-15
WO2008151440A1 (en) 2008-12-18
NZ598417A (en) 2013-06-28

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