JP5781542B2 - Ｅ．ｃｏｌｉキャリアタンパク質に結合体化した多糖免疫原 - Google Patents
Ｅ．ｃｏｌｉキャリアタンパク質に結合体化した多糖免疫原 Download PDFInfo
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- JP5781542B2 JP5781542B2 JP2012546520A JP2012546520A JP5781542B2 JP 5781542 B2 JP5781542 B2 JP 5781542B2 JP 2012546520 A JP2012546520 A JP 2012546520A JP 2012546520 A JP2012546520 A JP 2012546520A JP 5781542 B2 JP5781542 B2 JP 5781542B2
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| PCT/IB2010/003484 WO2011080595A2 (en) | 2009-12-30 | 2010-12-30 | Polysaccharide immunogens conjugated to e. coli carrier proteins |
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| US10988511B2 (en) * | 2009-07-07 | 2021-04-27 | Glaxosmithkline Biologicals Sa | Conserved Escherichia bacterial IG-like domain (group 1) protein (ORF405) immunogens |
| HUE034251T2 (en) | 2009-10-30 | 2018-02-28 | Glaxosmithkline Biologicals Sa | Purification of staphylococcus aureus type 5 and type 8 capsular saccharides |
| CN107913396B (zh) | 2010-08-23 | 2022-03-08 | 惠氏有限责任公司 | 脑膜炎萘瑟氏菌rLP2086抗原的稳定制剂 |
| AU2011300409B2 (en) | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
| EP2755994A2 (en) | 2011-09-14 | 2014-07-23 | Novartis AG | Escherichia coli vaccine combination |
| US9358284B2 (en) | 2011-09-14 | 2016-06-07 | Glaxosmithkline Biologicals Sa | Methods for making saccharide-protein glycoconjugates |
| RU2636350C2 (ru) * | 2011-11-07 | 2017-11-22 | Новартис Аг | МОЛЕКУЛА, СОДЕРЖАЩАЯ SPR0096 и SPR2021 |
| MY198910A (en) | 2012-03-09 | 2023-10-02 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| US20160184449A1 (en) * | 2013-02-28 | 2016-06-30 | University Of Massachusetts | Peptide-and amine-modified glucan particles for delivery of therapeutic cargoes |
| WO2014136064A2 (en) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
| WO2014158963A1 (en) * | 2013-03-12 | 2014-10-02 | Wellstat Vaccines, Llc | Antibodies targeted to fungal cell wall polysaccharides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| US9814769B2 (en) | 2014-09-30 | 2017-11-14 | Qatar University | Vaccines against pathogenic Escherichia coli and methods of using the same |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| WO2016132294A1 (en) | 2015-02-19 | 2016-08-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| BR112019003992A2 (pt) | 2016-09-02 | 2019-05-28 | Sanofi Pasteur Inc | vacina contra neisseria meningitidis |
| AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| WO2020018799A1 (en) * | 2018-07-18 | 2020-01-23 | The University Of Chicago | Compositions comprising sel1-derived peptides and methods of treatment/prevention of excess oxalate levels and associated conditions/diseases therewith |
| WO2021059181A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| EP4178596A1 (en) * | 2020-07-07 | 2023-05-17 | Danmarks Tekniske Universitet | Bacterial vehicle for engineering of non-phagocytic immune cells |
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| MXPA05013260A (es) | 2003-06-26 | 2006-03-09 | Chiron Corp | Composiciones inmunogenicas para chlamydia trachomatis. |
| EP1651262A2 (en) * | 2003-08-06 | 2006-05-03 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Process for preparing polysaccharide-protein conjugate vaccines |
| RU2236257C1 (ru) | 2003-09-15 | 2004-09-20 | Косяков Константин Сергеевич | Синтетический иммуноген для терапии и профилактики злоупотреблений наркотическими и психоактивными веществами |
| KR20110132416A (ko) | 2004-04-05 | 2011-12-07 | 화이자 프로덕츠 인코포레이티드 | 미세유체화된 수중유 유화액 및 백신 조성물 |
| JP2008530245A (ja) | 2005-02-18 | 2008-08-07 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド | 尿路病原性菌株由来の抗原 |
| SI1858920T1 (sl) * | 2005-02-18 | 2016-07-29 | Glaxosmithkline Biologicals S.A. | Proteini in nukleinske kisline iz escherichia coli, povezane z meningitisom/sepso |
| US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
| PE20110072A1 (es) | 2005-06-27 | 2011-02-04 | Glaxosmithkline Biolog Sa | Composicion inmunogenica |
| US8703095B2 (en) | 2005-07-07 | 2014-04-22 | Sanofi Pasteur S.A. | Immuno-adjuvant emulsion |
| US20100266626A1 (en) | 2007-11-26 | 2010-10-21 | Francesco Berti | Adjuvanted glucans |
| ITMI20081249A1 (it) * | 2008-07-09 | 2010-01-09 | Novartis Vaccines & Diagnostic | Immunogeni di escherichia coli con solubilità migliorata. |
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- 2010-12-30 US US13/520,338 patent/US9173954B2/en active Active
- 2010-12-30 ES ES10818096T patent/ES2707778T3/es active Active
- 2010-12-30 EP EP10818096.9A patent/EP2519265B1/en active Active
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| EP2519265A2 (en) | 2012-11-07 |
| US9173954B2 (en) | 2015-11-03 |
| US20120308600A1 (en) | 2012-12-06 |
| WO2011080595A3 (en) | 2012-07-26 |
| WO2011080595A2 (en) | 2011-07-07 |
| ES2707778T3 (es) | 2019-04-05 |
| JP2013516401A (ja) | 2013-05-13 |
| EP2519265B1 (en) | 2018-11-14 |
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