JP5770261B2 - （２０Ｓ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ジヒドロキシビタミンＤ３および（２０Ｒ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ヒドロキシビタミンＤ３ - Google Patents

（２０Ｓ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ジヒドロキシビタミンＤ３および（２０Ｒ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ヒドロキシビタミンＤ３ Download PDF

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JP5770261B2
JP5770261B2 JP2013501398A JP2013501398A JP5770261B2 JP 5770261 B2 JP5770261 B2 JP 5770261B2 JP 2013501398 A JP2013501398 A JP 2013501398A JP 2013501398 A JP2013501398 A JP 2013501398A JP 5770261 B2 JP5770261 B2 JP 5770261B2
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pharmaceutical composition
mmol
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dimethyl
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JP2013522369A (ja
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ヘクター エフ． デルカ
ヘクター エフ． デルカ
アグニエスツカ フローレス
アグニエスツカ フローレス
パウエル グジィヴァチュ
パウエル グジィヴァチュ
ローリ エイ． プラム
ローリ エイ． プラム
マーガレット クラーゲット−デイム
マーガレット クラーゲット−デイム
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ウイスコンシン アラムニ リサーチ ファンデーション
ウイスコンシン アラムニ リサーチ ファンデーション
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
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    • C07C2601/00—Systems containing only non-condensed rings
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    • C07C2601/14—The ring being saturated
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    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
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    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2013501398A 2010-03-23 2011-03-22 （２０Ｓ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ジヒドロキシビタミンＤ３および（２０Ｒ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ヒドロキシビタミンＤ３ Expired - Fee Related JP5770261B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31663110P 2010-03-23 2010-03-23
US61/316,631 2010-03-23
PCT/US2011/029432 WO2011119610A2 (en) 2010-03-23 2011-03-22 (20S)-2-METHYLENE-19-NOR-22-DIMETHYL-1α,25- DIHYDROXYVITAMIN D3 AND (20R)-2-METHYLENE-19-NOR-22- DIMETHYL-1α,25-HYDROXYVITAMIN D3

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JP2013522369A JP2013522369A (ja) 2013-06-13
JP2013522369A5 JP2013522369A5 (https=) 2014-05-08
JP5770261B2 true JP5770261B2 (ja) 2015-08-26

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US (1) US8604009B2 (https=)
EP (1) EP2556053B1 (https=)
JP (1) JP5770261B2 (https=)
AU (1) AU2011232633B2 (https=)
CA (1) CA2794006C (https=)
ES (1) ES2545403T3 (https=)
WO (1) WO2011119610A2 (https=)

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US9539231B2 (en) 2014-01-17 2017-01-10 The Regents Of The University Of Colorado, A Body Corporate Method for treating triple-negative breast cancer using AMPI-109
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US10369161B2 (en) 2014-12-30 2019-08-06 Wisconsin Alumni Research Foundation Use of 2-methylene-19-NOR-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism

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