JP5766124B2 - 炎症性疾患および自己免疫疾患の処置の組成物および方法 - Google Patents

炎症性疾患および自己免疫疾患の処置の組成物および方法 Download PDF

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JP5766124B2
JP5766124B2 JP2011548074A JP2011548074A JP5766124B2 JP 5766124 B2 JP5766124 B2 JP 5766124B2 JP 2011548074 A JP2011548074 A JP 2011548074A JP 2011548074 A JP2011548074 A JP 2011548074A JP 5766124 B2 JP5766124 B2 JP 5766124B2
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JP2012515778A (ja
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マーク エー． ギャビン，
マーク エー． ギャビン，
リー リー，
リー リー，
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2011548074A 2009-01-21 2010-01-20 炎症性疾患および自己免疫疾患の処置の組成物および方法 Active JP5766124B2 (ja)

Applications Claiming Priority (3)

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US14611109P 2009-01-21 2009-01-21
US61/146,111 2009-01-21
PCT/US2010/021519 WO2010085495A1 (en) 2009-01-21 2010-01-20 Compositions and methods of treating inflammatory and autoimmune diseases

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JP2014083388A Division JP2014133756A (ja) 2009-01-21 2014-04-15 炎症性疾患および自己免疫疾患の処置の組成物および方法

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JP2012515778A JP2012515778A (ja) 2012-07-12
JP2012515778A5 JP2012515778A5 (enExample) 2013-02-14
JP5766124B2 true JP5766124B2 (ja) 2015-08-19

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JP2011548074A Active JP5766124B2 (ja) 2009-01-21 2010-01-20 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2014083388A Withdrawn JP2014133756A (ja) 2009-01-21 2014-04-15 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2016092985A Withdrawn JP2016138140A (ja) 2009-01-21 2016-05-06 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2018031926A Withdrawn JP2018087244A (ja) 2009-01-21 2018-02-26 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2019191112A Withdrawn JP2020023550A (ja) 2009-01-21 2019-10-18 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2021143804A Withdrawn JP2021185191A (ja) 2009-01-21 2021-09-03 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2024085664A Pending JP2024105721A (ja) 2009-01-21 2024-05-27 炎症性疾患および自己免疫疾患の処置の組成物および方法

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JP2014083388A Withdrawn JP2014133756A (ja) 2009-01-21 2014-04-15 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2016092985A Withdrawn JP2016138140A (ja) 2009-01-21 2016-05-06 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2018031926A Withdrawn JP2018087244A (ja) 2009-01-21 2018-02-26 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2019191112A Withdrawn JP2020023550A (ja) 2009-01-21 2019-10-18 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2021143804A Withdrawn JP2021185191A (ja) 2009-01-21 2021-09-03 炎症性疾患および自己免疫疾患の処置の組成物および方法
JP2024085664A Pending JP2024105721A (ja) 2009-01-21 2024-05-27 炎症性疾患および自己免疫疾患の処置の組成物および方法

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US (5) US20110274650A1 (enExample)
EP (1) EP2382228B2 (enExample)
JP (7) JP5766124B2 (enExample)
AU (1) AU2010206840B2 (enExample)
CA (1) CA2749539C (enExample)
ES (1) ES2825173T5 (enExample)
MX (1) MX2011007647A (enExample)
WO (1) WO2010085495A1 (enExample)

Cited By (4)

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US11945852B2 (en) 2017-12-06 2024-04-02 Pandion Operations, Inc. IL-2 muteins and uses thereof
US12084484B2 (en) 2019-07-26 2024-09-10 Visterra, Inc. Interleukin-2 agents and uses thereof
US12098178B2 (en) 2020-12-04 2024-09-24 Visterra, Inc. Methods of using interleukin-2 agents
US12642840B2 (en) 2021-12-01 2026-06-02 Visterra, Inc. Methods of using interleukin-2 agents

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WO2012088446A1 (en) 2010-12-22 2012-06-28 Board Of Trustees Of The Leland Stanford Junior University Superagonists and antagonists of interleukin-2
CN105440123B (zh) 2011-02-10 2020-10-09 罗切格利卡特公司 突变体白介素-2多肽
EP3443979B2 (en) 2011-03-11 2026-05-20 Assistance Publique - Hôpitaux De Paris IL-2 DOSAGE REGIMEN FOR THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS
US9669071B2 (en) 2011-03-11 2017-06-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for stimulating T lymphocytes with IL-2
EA201892619A1 (ru) 2011-04-29 2019-04-30 Роше Гликарт Аг Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
US9481866B2 (en) * 2011-12-16 2016-11-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of producing T cell populations enriched for stable regulatory T-cells
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KR102493543B1 (ko) * 2014-07-21 2023-01-30 데리니아, 인크. 자가면역 질환의 치료를 위한 조절 t 세포를 선택적으로 활성화시키는 분자
JP6640834B2 (ja) 2014-08-11 2020-02-05 デリニア， インコーポレイテッド 自己免疫疾患の処置のために調節性ｔ細胞を選択的に活性化させる改変ｉｌ−２変異体
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