JP5739527B2 - ＲｈｏキナーゼインヒビターとしてのＮ−環式−３−（環状カルボニルアミノメチル）ベンズアミド誘導体 - Google Patents

ＲｈｏキナーゼインヒビターとしてのＮ−環式−３−（環状カルボニルアミノメチル）ベンズアミド誘導体 Download PDF

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JP5739527B2
JP5739527B2 JP2013518686A JP2013518686A JP5739527B2 JP 5739527 B2 JP5739527 B2 JP 5739527B2 JP 2013518686 A JP2013518686 A JP 2013518686A JP 2013518686 A JP2013518686 A JP 2013518686A JP 5739527 B2 JP5739527 B2 JP 5739527B2
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electrospray
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min compound
salt
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JP2013531013A5 (cg-RX-API-DMAC7.html
JP2013531013A (ja
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ブライアン ニコラス クック
ブライアン ニコラス クック
ジェニファー エイ コワルスキー
ジェニファー エイ コワルスキー
シアン リ
シアン リ
ダニエル リチャード マーシャル
ダニエル リチャード マーシャル
サビーン シュリアー
サビーン シュリアー
ロバート シブレー
ロバート シブレー
ラナ ルイーズ スミス−キーナン
ラナ ルイーズ スミス−キーナン
ファリバ ソレイマンザデー
ファリバ ソレイマンザデー
ロナルド ジョン ソーセック
ロナルド ジョン ソーセック
エリック リチャード ラウシュ ヤング
エリック リチャード ラウシュ ヤング
ユンロン ジャン
ユンロン ジャン
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP2013518686A 2010-07-07 2011-06-30 ＲｈｏキナーゼインヒビターとしてのＮ−環式−３−（環状カルボニルアミノメチル）ベンズアミド誘導体 Active JP5739527B2 (ja)

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US36203210P 2010-07-07 2010-07-07
US61/362,032 2010-07-07
PCT/US2011/042508 WO2012006203A1 (en) 2010-07-07 2011-06-30 N-cyclyl-3 - (cyclylcarbonylaminomethyl) benzamide derivatives as rho kinase inhibitors

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JP2013531013A5 JP2013531013A5 (cg-RX-API-DMAC7.html) 2014-08-14
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JP2020502066A (ja) 2016-11-21 2020-01-23 トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー キナーゼ阻害剤としての複素環式化合物
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SMT202400203T1 (it) 2017-11-24 2024-07-09 Jubilant Episcribe Llc Composti eterociclici come inibitori di prmt5
CA3093527A1 (en) 2018-03-13 2019-09-19 Jubilant Prodel LLC Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation
JP7490569B2 (ja) * 2018-04-24 2024-05-27 トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー キナーゼ阻害剤としてのアミド化合物、組成物および処置方法
CN109678815B (zh) * 2019-01-09 2022-11-29 中国药科大学 N-苄基苯甲酰胺类衍生物及其制备方法与制药用途
US20250074904A1 (en) * 2021-11-17 2025-03-06 The University Of North Carolina At Chapel Hill Nsd2-targeted checmical degraderts and compositions and methods of use thereof
CN116284045A (zh) * 2023-05-18 2023-06-23 西南交通大学 一种手性吲哚单元取代的四氢异喹啉化合物及其合成方法
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US20120165322A1 (en) 2012-06-28
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