JP5738196B2 - オーロラキナーゼ阻害剤および抗ｃｄ２０抗体の併用 - Google Patents

オーロラキナーゼ阻害剤および抗ｃｄ２０抗体の併用 Download PDF

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JP5738196B2
JP5738196B2 JP2011542127A JP2011542127A JP5738196B2 JP 5738196 B2 JP5738196 B2 JP 5738196B2 JP 2011542127 A JP2011542127 A JP 2011542127A JP 2011542127 A JP2011542127 A JP 2011542127A JP 5738196 B2 JP5738196 B2 JP 5738196B2
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treatment
ring
rituximab
combination
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JP2012513390A5 (https=
JP2012513390A (ja
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マーク マンフレーディ，
マーク マンフレーディ，
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Millennium Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2011542127A 2008-12-22 2009-12-15 オーロラキナーゼ阻害剤および抗ｃｄ２０抗体の併用 Active JP5738196B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20350908P 2008-12-22 2008-12-22
US61/203,509 2008-12-22
PCT/US2009/006560 WO2010074724A1 (en) 2008-12-22 2009-12-15 Combination of aurora kinase inhibitors and anti-cd20 antibodies

Publications (3)

Publication Number Publication Date
JP2012513390A JP2012513390A (ja) 2012-06-14
JP2012513390A5 JP2012513390A5 (https=) 2013-02-07
JP5738196B2 true JP5738196B2 (ja) 2015-06-17

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JP2011542127A Active JP5738196B2 (ja) 2008-12-22 2009-12-15 オーロラキナーゼ阻害剤および抗ｃｄ２０抗体の併用

Country Status (12)

Country Link
US (3) US20100183601A1 (https=)
EP (1) EP2376082B1 (https=)
JP (1) JP5738196B2 (https=)
KR (1) KR101741168B1 (https=)
CN (1) CN102264368B (https=)
AU (1) AU2009330727B2 (https=)
BR (1) BRPI0923579A2 (https=)
CA (1) CA2747326C (https=)
ES (1) ES2468391T3 (https=)
MX (1) MX2011006725A (https=)
RU (1) RU2535032C2 (https=)
WO (1) WO2010074724A1 (https=)

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WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
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Also Published As

Publication number Publication date
CA2747326C (en) 2017-05-16
KR101741168B1 (ko) 2017-05-29
MX2011006725A (es) 2011-09-15
US10391100B2 (en) 2019-08-27
JP2012513390A (ja) 2012-06-14
ES2468391T3 (es) 2014-06-16
EP2376082B1 (en) 2014-03-05
RU2535032C2 (ru) 2014-12-10
AU2009330727B2 (en) 2016-07-28
EP2376082A1 (en) 2011-10-19
RU2011130566A (ru) 2013-01-27
CN102264368B (zh) 2014-09-10
HK1160766A1 (en) 2012-08-17
CN102264368A (zh) 2011-11-30
CA2747326A1 (en) 2010-07-01
US20170296551A1 (en) 2017-10-19
US20100183601A1 (en) 2010-07-22
WO2010074724A1 (en) 2010-07-01
US20160271249A1 (en) 2016-09-22
KR20110114586A (ko) 2011-10-19
BRPI0923579A2 (pt) 2020-01-14
AU2009330727A1 (en) 2011-07-07

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