JP5735645B2 - 抗菌活性を有するペットフード組成物 - Google Patents
抗菌活性を有するペットフード組成物 Download PDFInfo
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- JP5735645B2 JP5735645B2 JP2013523304A JP2013523304A JP5735645B2 JP 5735645 B2 JP5735645 B2 JP 5735645B2 JP 2013523304 A JP2013523304 A JP 2013523304A JP 2013523304 A JP2013523304 A JP 2013523304A JP 5735645 B2 JP5735645 B2 JP 5735645B2
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- lactic acid
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- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/26—Compounds containing phosphorus
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/20—Shaping or working-up of animal feeding-stuffs by moulding, e.g. making cakes or briquettes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
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- A23K40/25—Shaping or working-up of animal feeding-stuffs by extrusion
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
- A23K50/42—Dry feed
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
- A23K50/48—Moist feed
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Description
本発明は2010年8月3日に出願された米国仮出願番号61/370328の利益を主張する。
本発明は、微生物汚染に耐性のある新規な飼料組成物、特にペットフード組成物、およびその製造方法に関する。
飼料組成物、特にペットフード組成物は、サルモネラ菌(Salmonella)、リステリア菌(Listeria)、大腸菌(E.Coli)およびクロストリジウム菌(Clostridium)などの病原菌による、微生物、特に細菌汚染にさらされる。この目的のための有効な抗菌剤の発見は、有効であると同時に、剤が安全で、食味が良好で、費用効果があり、安定である必要があるように、非常に困難なことがわかっている。特に乾燥ペットフード組成物は、加工後の段階で微生物汚染の影響を受けやすい。
US2004/0156884は、クロルヘキシジンを含む界面活性剤/ポリジメチルシロキサン乳化物が全体に含浸された治療的生皮ペットチューイ(chew)を記載する。
US4,049,835は、二酸化炭素包装雰囲気の使用が、予想外に多価アルコール、特に抗菌目的のために用いられる安定剤のプロピレングリコールおよびブチレングリコールの有効性を増加することが見出されるところでの、タンパク質含有フードを調製するための方法を開示する。
US4,212,894は、保存安定性のある中間水分飼料を調製するための方法を開示する。
US4,191,783は、pHを4.0から6.8の間に下げる酸、およびプロピレングリコール、1,3−ブタンジオールまたはそれらの混合物を含む組成物の添加により保存安定とされた高水分含有飼料を開示する。
US4,444,796は、ソルビン酸の微粉末をペットフード原料に混合することを含む、20重量%から45重量%の水分含量および6.0未満のpHを有する、良好な保管安定性のあるペットフードを製造するための方法を記載する。
EP1483975は、動物栄養における使用のための、乳酸またはその誘導体、および無機酸を含む抗菌組成物を開示する。
WO2006/004481は、核および被覆を含む抗菌酸性化給餌製品を開示する。
WO2004/019683は、定義された構造をもつ化合物を含む抗菌組成物を記載する。
本発明の適用のさらなる領域は、これ以降に提供される詳細な説明から明らかになるであろう。詳細な説明および特定の実施例、さらに示される本発明の好ましい実施形態は例示の目的のみを意図し、発明の範囲を限定する意図ではないことが理解されるべきである。
好ましい実施形態の以下の記載は単に事実上の典型例であり、本発明、その応用、または用途を限定する意図では決してない。
a.キブル生地を形成する、湿潤または乾燥原料を上昇温度にて混合することによるプレコンディショニング;
b.キブル生地の高温高圧での押出し;
c.押出しキブルの乾燥;および
d.局所用液(topical liquid)および/または乾燥原料での乾燥した押出しキブルのエンロービング;
を含み、抗菌効果を組成物に付与する原料がキブルに段階aおよび/またはbで、キブルの約0.1重量%から約3重量%の量で適用される。
(a)約0重量%から約95重量%のタンパク質、
(b)約0%から約75%の炭水化物、
(c)約0%から約50%の脂肪、
(d)約0%から約40%の食物繊維、および
(e)約0%から約15%の1種類以上の栄養調整剤。
本試験は、典型的に細菌の抗生物質感受性について使用され、潜在的な抗菌(AMI)活性をもつ原料によるサルモネラ菌増殖の抑制を測定するために適応された。直径が約5mmである濾紙のディスクは、0.1%、0.2%、および0.4%の溶液で浸されたオレガノを除いて、1%、2%、および3%でAMIに浸され、サルモネラ菌(S.aarhus、S.muenster E1およびS.worthington)の標準化された懸濁液が塗布された、テトラフェニルテトラゾリウム(TTC)含有標準寒天培地のペトリ皿に置かれた。サルモネラ菌培養物が飽和した濾紙に関してどれくらい密接に増殖したかを測定することによって、AMIの効力が確定された。
抗菌性原料の最小抑制濃度(MIC)は、サルモネラ菌の増殖を依然として阻害するであろう製品の最大希釈度として定義される。連続した希釈物(0〜3%、オレガノの0〜0.3%を除く)が細菌増殖培地のAMIで作成され、試験管に注がれた。試験生物(S.aarhus、S.muenster E1およびS.worthington)はその後AMI原料の希釈物に最終濃度106または103cfu/gで添加され、30℃で一晩培養され、濁りまたは生菌数で増殖が採点された。
AMI(0〜3%)で被覆された最終製品は、負荷実験で試験された。各々のキブルの100gキブルがサルモネラ菌(S.aarhus、S.muenster E1およびS.worthington)を最終濃度106で接種され、30℃で培養された。サルモネラ菌数計測はあらかじめ定められた時間間隔で実施された。食味実験(2ボウル、2日間)はAMIのない対照に対するAMI含有成犬用および成猫用ペットフード組成物で実施された。
試料調製および培養
サルモネラ属での乾燥ドッグフードの最終製品汚染は4箇所に分割し得る−1)エアリフトまたは乾燥機入り口、2)乾燥機中、3)非被覆キブル(Ro−Tap登録商標を経てエンローバーまで)および4)被覆キブル(エンローバーから包装系を経て)。キブルは押出機で高温高圧で処理される。これらの条件(122℃および15psi)は、レトルト内部でみられ、商業的無菌でキブルを製造すると信じられているものと同様である。湿ったキブルは押出し機に残され、100℃に戻される(flash back)。圧力の急激な低下がキブルを膨化させ、その円形および目標の密度を形成することをもたらす。キブルの表面は、押出し機から乾燥機へのエアリフトにおいて輸送する高容量の空気で急速に冷却される。蒸発冷却は表面温度を約50℃に落とし、その後キブルは乾燥機から熱を吸収する。乾燥機の出口で、キブルは再度約70℃に加温され、製造設備の大気条件に依存する冷たい湿潤な空気にさらされ得るRo−Tap登録商標でふるい分けされる。キブルは次いでエンロービング(局所液および乾燥原料で被覆)される。エンローバーに続いて、キブルは大気条件まで冷却され、包装が行われ、最小の水分損失がある。
局所被覆およびプレコンディショニング段階において添加された乳酸含有の製剤の様々なレベルでの犬用キブル製剤の食味が、対照に対して、犬で、摂取比0.5は犬が対照飼料と試験で同じ摂取を有したことを示すところの、0.5〜0.77の間の摂取比で試験された。結果は表13に示される。
Claims (6)
- 組成物に抗菌効果を付与するための有効量の原料を含むペットフード組成物であって、
原料が腐敗微生物に対して活性を有し、組成物中に0.1重量%から3重量%の量であり、かつ組成物は乾燥キャットフードまたは乾燥ドッグフードであり、かつ原料が乳酸であり、
ここで、該組成物は5.5未満のpHを有する、ペットフード組成物。 - 組成物が0.13%から3%の乳酸を含み、組成物のpHが4から5である、請求項1に記載のペットフード組成物。
- 以下の工程:
a.キブル生地を形成する、湿潤または乾燥原料を上昇温度にて混合することによるプレコンディショニング;
b.キブル生地の高温高圧での押出し;
c.押出しキブルの乾燥;および
d.局所用液および/または乾燥原料での乾燥したキブルのエンロービング;
を含むペットフード組成物の製造方法であって、抗菌効果を組成物に付与する原料がキブルに段階aおよび/またはbで、組成物の0.1重量%から3重量%の量で適用され、原料が腐敗微生物に対して活性を有し、組成物は乾燥キャットフードまたは乾燥ドッグフードであり、かつ原料が乳酸であり、
ここで、該組成物は5.5未満のpHを有する、ペットフード組成物の製造方法。 - 組成物が0.13%から3%の乳酸を含み、組成物のpHが4から5である、請求項3に記載の製造方法。
- 組成物に抗菌効果を付与するための有効量の原料を添加することを含む、ペットフード組成物の微生物増殖を阻害する方法であって、原料が組成物中に0.1重量%から3重量%の量であり、組成物は乾燥キャットフードまたは乾燥ドッグフードであり、かつ原料が乳酸であり、
ここで、該組成物は5.5未満のpHを有する、方法。 - 組成物が0.13%から3%の乳酸を含み、4から5のpHを有する、請求項5に記載の方法。
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US37032810P | 2010-08-03 | 2010-08-03 | |
US61/370,328 | 2010-08-03 | ||
PCT/US2011/046422 WO2012018913A1 (en) | 2010-08-03 | 2011-08-03 | Pet food compositions having antimicrobial activity |
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- 2011-08-03 ES ES11745645.9T patent/ES2600312T3/es active Active
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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JP7277228B2 (ja) | 2019-04-12 | 2023-05-18 | キヤノン株式会社 | 液体収納容器の製造方法 |
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AU2011285786B2 (en) | 2014-02-06 |
US20220151264A1 (en) | 2022-05-19 |
CA2805500A1 (en) | 2012-02-09 |
EP2597963B1 (en) | 2016-07-27 |
CN103140141A (zh) | 2013-06-05 |
ZA201300577B (en) | 2015-10-28 |
JP2013534139A (ja) | 2013-09-02 |
CA2805500C (en) | 2015-01-27 |
EP3090634A1 (en) | 2016-11-09 |
RU2546879C2 (ru) | 2015-04-10 |
AU2011285786A1 (en) | 2013-02-07 |
WO2012018913A1 (en) | 2012-02-09 |
RU2013109298A (ru) | 2014-09-10 |
BR112013002685A2 (pt) | 2016-05-31 |
US20130122164A1 (en) | 2013-05-16 |
DK2597963T3 (da) | 2016-10-24 |
CN105558385A (zh) | 2016-05-11 |
US20170042193A1 (en) | 2017-02-16 |
ES2600312T3 (es) | 2017-02-08 |
US20200221735A1 (en) | 2020-07-16 |
EP2597963A1 (en) | 2013-06-05 |
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