JP5731515B2 - ２−チオヒスチジンなどの合成方法 - Google Patents

２−チオヒスチジンなどの合成方法 Download PDF

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Publication number
JP5731515B2
JP5731515B2 JP2012532584A JP2012532584A JP5731515B2 JP 5731515 B2 JP5731515 B2 JP 5731515B2 JP 2012532584 A JP2012532584 A JP 2012532584A JP 2012532584 A JP2012532584 A JP 2012532584A JP 5731515 B2 JP5731515 B2 JP 5731515B2
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Japan
Prior art keywords
formula
compound
mixture
acid
stereoisomer
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Expired - Fee Related
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JP2012532584A
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English (en)
Japanese (ja)
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JP2013506705A (ja
JP2013506705A5 (zh
Inventor
エーデルメイヤー、イレーヌ
ドネイ、シルビアン
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Tetrahedron SAS
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Tetrahedron SAS
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
JP2012532584A 2009-10-06 2010-10-06 ２−チオヒスチジンなどの合成方法 Expired - Fee Related JP5731515B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0956968A FR2950890B1 (fr) 2009-10-06 2009-10-06 Procede de synthese de la 2-thiohistidine et analogues
FR0956968 2009-10-06
PCT/EP2010/064947 WO2011042478A1 (fr) 2009-10-06 2010-10-06 Procede de synthese de la 2-thiohistidine et analogues

Publications (3)

Publication Number Publication Date
JP2013506705A JP2013506705A (ja) 2013-02-28
JP2013506705A5 JP2013506705A5 (zh) 2013-11-21
JP5731515B2 true JP5731515B2 (ja) 2015-06-10

Family

ID=41664356

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012532584A Expired - Fee Related JP5731515B2 (ja) 2009-10-06 2010-10-06 ２−チオヒスチジンなどの合成方法

Country Status (14)

Country Link
US (1) US8835477B2 (zh)
EP (1) EP2486019B1 (zh)
JP (1) JP5731515B2 (zh)
KR (1) KR101773995B1 (zh)
CN (1) CN102596915B (zh)
AU (1) AU2010305397B2 (zh)
BR (1) BR112012007944A2 (zh)
CA (1) CA2776833C (zh)
ES (1) ES2540279T3 (zh)
FR (1) FR2950890B1 (zh)
HU (1) HUE025487T2 (zh)
IN (1) IN2012DN03819A (zh)
RU (1) RU2548153C2 (zh)
WO (1) WO2011042478A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3021655B1 (fr) 2014-05-30 2016-07-08 Tetrahedron Nouveaux composes de type 5-acylsulfanyl-histidine en tant que precurseurs des 5-sulfanylhistidines correspondantes et de leurs disulfures
JP6864131B1 (ja) * 2020-03-04 2021-04-28 長瀬産業株式会社 Ｌ−エルゴチオネイン含有組成物
EP4326302A1 (en) * 2021-04-22 2024-02-28 University of Vermont and State Agricultural College Substitution of histidine with 2-thiohistidine in bioactive peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707087B1 (fr) * 1993-06-28 1995-10-13 Bioxytech Nouveau procédé de préparation de l'ergothionéine.
FR2714380B1 (fr) 1993-12-24 1996-05-24 Bioxytech Utilisation de dérivés 2-mercapto-imidazole substitués en position 4 (ou 5) comme agents antioxydants, leur procédé de préparation et leurs applications en pharmacie, cosmétique ou alimentaire.
EP0939628B1 (en) * 1996-07-22 2003-03-05 Monsanto Company Thiol sulfone metalloprotease inhibitors
CN101426763A (zh) * 2000-10-11 2009-05-06 埃斯佩里安医疗公司 用于胆固醇治疗和相关应用的硫化物和二硫化物化合物和组合物
US7767826B2 (en) * 2007-10-05 2010-08-03 Pharmatech International, Inc. Process for the synthesis of L-(+)-ergothioneine
FR2950889B1 (fr) 2009-10-06 2011-11-18 Tetrahedron Procede de synthese de l'ergothioneine et analogues

Also Published As

Publication number Publication date
ES2540279T3 (es) 2015-07-09
KR101773995B1 (ko) 2017-09-01
CA2776833A1 (fr) 2011-04-14
JP2013506705A (ja) 2013-02-28
CN102596915A (zh) 2012-07-18
WO2011042478A1 (fr) 2011-04-14
FR2950890B1 (fr) 2011-12-30
US20120330029A1 (en) 2012-12-27
FR2950890A1 (fr) 2011-04-08
IN2012DN03819A (zh) 2015-08-28
RU2012117977A (ru) 2013-11-20
EP2486019B1 (fr) 2015-03-25
CA2776833C (fr) 2019-03-19
CN102596915B (zh) 2016-04-20
AU2010305397B2 (en) 2014-07-10
EP2486019A1 (fr) 2012-08-15
RU2548153C2 (ru) 2015-04-20
US8835477B2 (en) 2014-09-16
AU2010305397A1 (en) 2012-05-24
HUE025487T2 (en) 2016-04-28
BR112012007944A2 (pt) 2015-09-22
KR20120100977A (ko) 2012-09-12

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