JP5707534B2 - 抗癌剤 - Google Patents

抗癌剤 Download PDF

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Publication number
JP5707534B2
JP5707534B2 JP2014507890A JP2014507890A JP5707534B2 JP 5707534 B2 JP5707534 B2 JP 5707534B2 JP 2014507890 A JP2014507890 A JP 2014507890A JP 2014507890 A JP2014507890 A JP 2014507890A JP 5707534 B2 JP5707534 B2 JP 5707534B2
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JP
Japan
Prior art keywords
burdock
arctigenin
arctiin
extract
glucose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2014507890A
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English (en)
Japanese (ja)
Other versions
JPWO2013146734A1 (ja
Inventor
江角　浩安
浩安 江角
公史 池田
公史 池田
千香 三好
千香 三好
重利 門田
重利 門田
敏樹 大窪
敏樹 大窪
与茂田　敏
敏 与茂田
布施　貴史
貴史 布施
孝則 川島
孝則 川島
殖幹 千葉
殖幹 千葉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kracie Pharma Ltd
National Cancer Center Japan
University of Toyama NUC
Original Assignee
Kracie Pharma Ltd
National Cancer Center Japan
University of Toyama NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kracie Pharma Ltd, National Cancer Center Japan, University of Toyama NUC filed Critical Kracie Pharma Ltd
Priority to JP2014507890A priority Critical patent/JP5707534B2/ja
Application granted granted Critical
Publication of JP5707534B2 publication Critical patent/JP5707534B2/ja
Publication of JPWO2013146734A1 publication Critical patent/JPWO2013146734A1/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014507890A 2012-03-26 2013-03-26 抗癌剤 Active JP5707534B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2014507890A JP5707534B2 (ja) 2012-03-26 2013-03-26 抗癌剤

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2012069964 2012-03-26
JP2012069964 2012-03-26
JP2014507890A JP5707534B2 (ja) 2012-03-26 2013-03-26 抗癌剤
PCT/JP2013/058692 WO2013146734A1 (ja) 2012-03-26 2013-03-26 抗癌剤

Publications (2)

Publication Number Publication Date
JP5707534B2 true JP5707534B2 (ja) 2015-04-30
JPWO2013146734A1 JPWO2013146734A1 (ja) 2015-12-14

Family

ID=49259985

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014507890A Active JP5707534B2 (ja) 2012-03-26 2013-03-26 抗癌剤

Country Status (8)

Country Link
US (1) US9700572B2 (enExample)
EP (1) EP2832355A4 (enExample)
JP (1) JP5707534B2 (enExample)
KR (1) KR20140139073A (enExample)
CN (1) CN104379143A (enExample)
HK (1) HK1203811A1 (enExample)
IN (1) IN2014MN01973A (enExample)
WO (1) WO2013146734A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5696191B2 (ja) * 2013-04-27 2015-04-08 クラシエ製薬株式会社 抗癌幹細胞剤
JP2016079163A (ja) * 2014-10-14 2016-05-16 医療環境テクノ株式会社 腫瘍を処置するための組成物およびその製造方法
JP6773665B2 (ja) * 2015-10-09 2020-10-21 クラシエ製薬株式会社 血管壁強化剤、血管壁を強化する方法および血管網形成抑制剤
JP6876502B2 (ja) * 2016-04-25 2021-05-26 クラシエホールディングス株式会社 未分化細胞除去剤
CN105832719B (zh) * 2016-04-28 2019-05-03 上海中医药大学附属龙华医院 牛蒡苷元在调节pp2a活性中的应用
CN109045010B (zh) * 2018-09-19 2021-03-30 淮海工学院 一种具有抗肿瘤作用的药物组合物及其应用
US11412028B2 (en) 2019-02-08 2022-08-09 Bluepipes, Inc. Online platform and a method for facilitating sharing of data between users
JP7526562B2 (ja) * 2019-11-21 2024-08-01 クラシエ株式会社 レンギョウ葉の加工方法および加工レンギョウ葉

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002065298A (ja) 2000-08-30 2002-03-05 Japan Science & Technology Corp 薬剤成分のスクリーニング方法
CN101036644A (zh) * 2006-03-13 2007-09-19 海南盛科天然药物研究院有限公司 含牛蒡子苷元的药用组合物及其制备方法
KR20080107794A (ko) * 2007-06-08 2008-12-11 경남대학교 산학협력단 우방자 추출물을 함유하는 항암 조성물
EP2412377B1 (en) * 2009-03-27 2018-12-26 Kracie Holdings Ltd. Burdock fruit extract containing arctigenin at high content and process for producing same
KR101538450B1 (ko) 2010-09-27 2015-07-22 구라시에제약 주식회사 악티게닌 함유 우방자 추출물 및 그 제조방법
CN102440986B (zh) * 2010-10-08 2014-12-03 鲁南制药集团股份有限公司 牛蒡子苷元在制备防治辐射或化学品引起的骨髓抑制的药物中的用途

Also Published As

Publication number Publication date
HK1203811A1 (en) 2015-11-06
IN2014MN01973A (enExample) 2015-07-10
WO2013146734A1 (ja) 2013-10-03
US20150196576A1 (en) 2015-07-16
JPWO2013146734A1 (ja) 2015-12-14
US9700572B2 (en) 2017-07-11
EP2832355A1 (en) 2015-02-04
CN104379143A (zh) 2015-02-25
KR20140139073A (ko) 2014-12-04
EP2832355A4 (en) 2015-12-23

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