IN2014MN01973A - - Google Patents
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- Publication number
- IN2014MN01973A IN2014MN01973A IN1973MUN2014A IN2014MN01973A IN 2014MN01973 A IN2014MN01973 A IN 2014MN01973A IN 1973MUN2014 A IN1973MUN2014 A IN 1973MUN2014A IN 2014MN01973 A IN2014MN01973 A IN 2014MN01973A
- Authority
- IN
- India
- Prior art keywords
- arctigenin
- present
- anticancer agent
- arctiin
- daily dose
- Prior art date
Links
- NQWVSMVXKMHKTF-JKSUJKDBSA-N (-)-Arctigenin Chemical compound C1=C(OC)C(OC)=CC=C1C[C@@H]1[C@@H](CC=2C=C(OC)C(O)=CC=2)C(=O)OC1 NQWVSMVXKMHKTF-JKSUJKDBSA-N 0.000 abstract 4
- YYGRXNOXOVZIKE-UHFFFAOYSA-N Arctigenin Natural products COC1CCC(CC2COC(=O)C2CC3CCC(O)C(C3)OC)CC1OC YYGRXNOXOVZIKE-UHFFFAOYSA-N 0.000 abstract 4
- OIFFJDGSLVHPCW-UHFFFAOYSA-N Guayarol Natural products COc1ccc(CC2C(Cc3ccc(O)c(O)c3)COC2=O)cc1OC OIFFJDGSLVHPCW-UHFFFAOYSA-N 0.000 abstract 4
- NQWVSMVXKMHKTF-UHFFFAOYSA-N L-Arctigenin Natural products C1=C(OC)C(OC)=CC=C1CC1C(CC=2C=C(OC)C(O)=CC=2)C(=O)OC1 NQWVSMVXKMHKTF-UHFFFAOYSA-N 0.000 abstract 4
- NWFYESYCEQICQP-UHFFFAOYSA-N methylmatairesinol Natural products C1=C(OC)C(OC)=CC=C1CC1C(=O)OCC1CC1=CC=C(O)C(OC)=C1 NWFYESYCEQICQP-UHFFFAOYSA-N 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 239000002246 antineoplastic agent Substances 0.000 abstract 3
- XOJVHLIYNSOZOO-SWOBOCGESA-N Arctiin Chemical compound C1=C(OC)C(OC)=CC=C1C[C@@H]1[C@@H](CC=2C=C(OC)C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)=CC=2)C(=O)OC1 XOJVHLIYNSOZOO-SWOBOCGESA-N 0.000 abstract 2
- BPYGTFFYYOWDBC-LOVSFRALSA-N arctiin Natural products COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc3ccc(O[C@@H]4O[C@H](C)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)cc1OC BPYGTFFYYOWDBC-LOVSFRALSA-N 0.000 abstract 2
- 240000005528 Arctium lappa Species 0.000 abstract 1
- 235000003130 Arctium lappa Nutrition 0.000 abstract 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 abstract 1
- 201000002528 pancreatic cancer Diseases 0.000 abstract 1
- 208000008443 pancreatic carcinoma Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012069964 | 2012-03-26 | ||
| PCT/JP2013/058692 WO2013146734A1 (ja) | 2012-03-26 | 2013-03-26 | 抗癌剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN01973A true IN2014MN01973A (enExample) | 2015-07-10 |
Family
ID=49259985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1973MUN2014 IN2014MN01973A (enExample) | 2012-03-26 | 2013-03-26 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9700572B2 (enExample) |
| EP (1) | EP2832355A4 (enExample) |
| JP (1) | JP5707534B2 (enExample) |
| KR (1) | KR20140139073A (enExample) |
| CN (1) | CN104379143A (enExample) |
| HK (1) | HK1203811A1 (enExample) |
| IN (1) | IN2014MN01973A (enExample) |
| WO (1) | WO2013146734A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11412028B2 (en) | 2019-02-08 | 2022-08-09 | Bluepipes, Inc. | Online platform and a method for facilitating sharing of data between users |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5696191B2 (ja) * | 2013-04-27 | 2015-04-08 | クラシエ製薬株式会社 | 抗癌幹細胞剤 |
| JP2016079163A (ja) * | 2014-10-14 | 2016-05-16 | 医療環境テクノ株式会社 | 腫瘍を処置するための組成物およびその製造方法 |
| JP6773665B2 (ja) * | 2015-10-09 | 2020-10-21 | クラシエ製薬株式会社 | 血管壁強化剤、血管壁を強化する方法および血管網形成抑制剤 |
| JP6876502B2 (ja) * | 2016-04-25 | 2021-05-26 | クラシエホールディングス株式会社 | 未分化細胞除去剤 |
| CN105832719B (zh) * | 2016-04-28 | 2019-05-03 | 上海中医药大学附属龙华医院 | 牛蒡苷元在调节pp2a活性中的应用 |
| CN109045010B (zh) * | 2018-09-19 | 2021-03-30 | 淮海工学院 | 一种具有抗肿瘤作用的药物组合物及其应用 |
| JP7526562B2 (ja) * | 2019-11-21 | 2024-08-01 | クラシエ株式会社 | レンギョウ葉の加工方法および加工レンギョウ葉 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002065298A (ja) | 2000-08-30 | 2002-03-05 | Japan Science & Technology Corp | 薬剤成分のスクリーニング方法 |
| CN101036644A (zh) * | 2006-03-13 | 2007-09-19 | 海南盛科天然药物研究院有限公司 | 含牛蒡子苷元的药用组合物及其制备方法 |
| KR20080107794A (ko) * | 2007-06-08 | 2008-12-11 | 경남대학교 산학협력단 | 우방자 추출물을 함유하는 항암 조성물 |
| EP2412377B1 (en) * | 2009-03-27 | 2018-12-26 | Kracie Holdings Ltd. | Burdock fruit extract containing arctigenin at high content and process for producing same |
| KR101538450B1 (ko) | 2010-09-27 | 2015-07-22 | 구라시에제약 주식회사 | 악티게닌 함유 우방자 추출물 및 그 제조방법 |
| CN102440986B (zh) * | 2010-10-08 | 2014-12-03 | 鲁南制药集团股份有限公司 | 牛蒡子苷元在制备防治辐射或化学品引起的骨髓抑制的药物中的用途 |
-
2013
- 2013-03-26 IN IN1973MUN2014 patent/IN2014MN01973A/en unknown
- 2013-03-26 WO PCT/JP2013/058692 patent/WO2013146734A1/ja not_active Ceased
- 2013-03-26 CN CN201380016479.1A patent/CN104379143A/zh active Pending
- 2013-03-26 KR KR1020147029903A patent/KR20140139073A/ko not_active Ceased
- 2013-03-26 JP JP2014507890A patent/JP5707534B2/ja active Active
- 2013-03-26 EP EP13767892.6A patent/EP2832355A4/en not_active Ceased
- 2013-03-26 HK HK15103344.0A patent/HK1203811A1/xx unknown
-
2014
- 2014-09-24 US US14/494,637 patent/US9700572B2/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11412028B2 (en) | 2019-02-08 | 2022-08-09 | Bluepipes, Inc. | Online platform and a method for facilitating sharing of data between users |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1203811A1 (en) | 2015-11-06 |
| WO2013146734A1 (ja) | 2013-10-03 |
| US20150196576A1 (en) | 2015-07-16 |
| JPWO2013146734A1 (ja) | 2015-12-14 |
| US9700572B2 (en) | 2017-07-11 |
| JP5707534B2 (ja) | 2015-04-30 |
| EP2832355A1 (en) | 2015-02-04 |
| CN104379143A (zh) | 2015-02-25 |
| KR20140139073A (ko) | 2014-12-04 |
| EP2832355A4 (en) | 2015-12-23 |
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