JP5702384B2 - 中空マイクロニードルアレイ - Google Patents

中空マイクロニードルアレイ Download PDF

Info

Publication number
JP5702384B2
JP5702384B2 JP2012522974A JP2012522974A JP5702384B2 JP 5702384 B2 JP5702384 B2 JP 5702384B2 JP 2012522974 A JP2012522974 A JP 2012522974A JP 2012522974 A JP2012522974 A JP 2012522974A JP 5702384 B2 JP5702384 B2 JP 5702384B2
Authority
JP
Japan
Prior art keywords
fluid
reservoir
applicator
stored energy
energy device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012522974A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013500773A5 (OSRAM
JP2013500773A (ja
Inventor
エー．ゴンザレス バーナード
エー．ゴンザレス バーナード
エー．バートン スコット
エー．バートン スコット
フ ジャ
フ ジャ
ング チン−イー
ング チン−イー
パトリック シマーズ ライアン
パトリック シマーズ ライアン
ジェイ．ギルバート トーマス
ジェイ．ギルバート トーマス
エム．バーク シーン
エム．バーク シーン
エー．ハーキンス ロバート
エー．ハーキンス ロバート
エー．シュレイフ ラリー
エー．シュレイフ ラリー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of JP2013500773A publication Critical patent/JP2013500773A/ja
Publication of JP2013500773A5 publication Critical patent/JP2013500773A5/ja
Application granted granted Critical
Publication of JP5702384B2 publication Critical patent/JP5702384B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14506—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons mechanically driven, e.g. spring or clockwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP2012522974A 2009-07-31 2010-07-27 中空マイクロニードルアレイ Expired - Fee Related JP5702384B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23034709P 2009-07-31 2009-07-31
US61/230,347 2009-07-31
PCT/US2010/043414 WO2011014514A1 (en) 2009-07-31 2010-07-27 Hollow microneedle arrays

Publications (3)

Publication Number Publication Date
JP2013500773A JP2013500773A (ja) 2013-01-10
JP2013500773A5 JP2013500773A5 (OSRAM) 2013-09-12
JP5702384B2 true JP5702384B2 (ja) 2015-04-15

Family

ID=43017143

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012522974A Expired - Fee Related JP5702384B2 (ja) 2009-07-31 2010-07-27 中空マイクロニードルアレイ

Country Status (11)

Country Link
US (2) US10010706B2 (OSRAM)
EP (2) EP3354312A1 (OSRAM)
JP (1) JP5702384B2 (OSRAM)
KR (1) KR101712226B1 (OSRAM)
CN (1) CN102497909B (OSRAM)
AU (1) AU2010276511B2 (OSRAM)
BR (1) BR112012001685B8 (OSRAM)
CA (1) CA2769102C (OSRAM)
ES (1) ES2661063T3 (OSRAM)
RU (1) RU2508135C2 (OSRAM)
WO (1) WO2011014514A1 (OSRAM)

Families Citing this family (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
US9119945B2 (en) 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
JP5535623B2 (ja) 2006-06-30 2014-07-02 アッヴィ バイオテクノロジー リミテッド 自動注射装置
EP2146689B1 (en) 2007-04-16 2020-08-12 Corium, Inc. Solvent-cast microneedle arrays containing active
EP2195052B1 (en) 2007-10-02 2019-09-04 Medimop Medical Projects Ltd. External drug pump
BR112012024238A2 (pt) 2010-03-25 2019-09-24 New Injection Systems Ltd injetor
AU2011242602B2 (en) 2010-04-21 2015-06-18 Abbvie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
CA2798145C (en) 2010-05-04 2022-10-18 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
AU2015203703B2 (en) * 2010-05-20 2018-01-18 Becton, Dickinson And Company Drug delivery device
EP3527241B1 (en) * 2010-05-20 2020-12-23 Becton, Dickinson and Company Drug delivery device
GB2483505B (en) * 2010-09-13 2012-10-10 Ndm Technologies Ltd Devices for transdermal drug delivery
WO2012061556A1 (en) * 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
BR112013018905B1 (pt) 2011-01-24 2021-07-13 Abbvie Biotechnology Ltd Dispositivos de injeção automática que têm superfícies de pega sobremoldadas.
US20140052067A1 (en) * 2011-03-18 2014-02-20 Universite Libre De Bruxelles Devices for puncturing for a human or animal body's membrane
CN102727992A (zh) * 2011-03-31 2012-10-17 株式会社汉比特科技与创新 印章式针组件
MX345747B (es) 2011-04-21 2017-02-14 Abbvie Inc Dispositivo de inyección automático portable.
CA2841785A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
EP2753377B1 (en) 2011-09-07 2022-05-04 Kindeva Drug Delivery L.P. Delivery system for hollow microneedle arrays
AU2012308764C1 (en) * 2011-09-13 2017-05-25 Unitract Syringe Pty Ltd Sterile fluid pathway connection to drug containers for drug delivery pumps
US10010707B2 (en) 2011-10-12 2018-07-03 3M Innovative Properties Company Integrated microneedle array delivery system
CN102327656B (zh) * 2011-10-18 2013-05-08 清华大学 一次性阵列式微型注射针头
BR112014013151B1 (pt) 2011-11-30 2022-02-08 3M Innovative Properties Company Dispositivo médico compreendendo microagulhas incluindo um agente terapêutico peptídeo e um aminoácido, métodos para produzir o dispositivo e método para estabilizar um agente terapêutico peptídeo
SG11201405643RA (en) * 2012-03-16 2014-10-30 Univ Singapore A novel method to fabricate polymeric microneedles
JP5903016B2 (ja) 2012-06-27 2016-04-13 コスメディ製薬株式会社 マイクロニードルパッチの保護離型シート
WO2014058746A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
US10300260B2 (en) 2012-10-10 2019-05-28 3M Innovative Properties Company Applicator and method for applying a microneedle device to skin
WO2014062538A1 (en) 2012-10-19 2014-04-24 3M Innovative Properties Company Polysaccharide-containing hydrogels, compositions, articles, and methods
USD705422S1 (en) 2012-10-26 2014-05-20 3M Innovative Properties Company Microneedle applicator
USD693921S1 (en) 2012-10-26 2013-11-19 3M Innovative Properties Company Microneedle applicator
US9789299B2 (en) 2012-11-16 2017-10-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
DK3081249T3 (da) * 2012-11-21 2021-03-15 Amgen Inc Lægemiddeladministrationsanordning
BR112015011662A2 (pt) 2012-11-23 2017-07-11 New Injection Systems Ltd montagem de auto-injetor
BR112015014969B1 (pt) 2012-12-21 2021-12-07 Corium, Inc Aparelho de microestruturas e método de fabricar um aparelho de microestruturas
US10549079B2 (en) 2012-12-21 2020-02-04 3M Innovative Properties Company Adhesive assemblies and microneedle injection apparatuses comprising same
US10105524B2 (en) 2012-12-27 2018-10-23 3M Innovative Properties Company Article with hollow microneedles and method of making
US20150352295A1 (en) * 2013-01-08 2015-12-10 3M Innovative Properties Company Application For Applying A Microneedle Device To Skin
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
JP6522523B2 (ja) * 2013-02-28 2019-05-29 ソレント・セラピューティクス・インコーポレイテッド 経皮的薬物送達装置
EP4094799A1 (en) * 2013-03-12 2022-11-30 Corium, Inc. Microprojection applicators
WO2014151654A1 (en) 2013-03-15 2014-09-25 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
CA2903459C (en) * 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
SG11201507885TA (en) 2013-03-22 2015-11-27 3M Innovative Properties Co Microneedle applicator comprising a counter assembly
US20140309096A1 (en) * 2013-04-15 2014-10-16 Becton, Dickinson And Company Biological Fluid Collection Device and Biological Fluid Separation System
BR112015029865B8 (pt) * 2013-05-31 2023-05-16 3M Innovative Properties Company Aparelho para injeção com microagulhas compreendendo um atuador invertido
US9872975B2 (en) * 2013-05-31 2018-01-23 3M Innovative Properties Company Microneedle injection and infusion apparatus and method of using same
US9895520B2 (en) 2013-05-31 2018-02-20 3M Innovative Properties Company Microneedle injection apparatus comprising a dual cover
EP3020445A4 (en) 2013-07-08 2017-03-08 Toppan Printing Co., Ltd. Hollow needle-like body device
EP3021931B1 (en) 2013-07-16 2021-09-01 Kindeva Drug Delivery L.P. Hollow microneedle array article
WO2015009524A1 (en) 2013-07-16 2015-01-22 3M Innovative Properties Company Hollow microneedle with beveled tip
WO2015009523A1 (en) 2013-07-16 2015-01-22 3M Innovative Properties Company Hollow microneedle with bevel opening
CN105407957A (zh) 2013-07-16 2016-03-16 3M创新有限公司 一种包括微针的制品
EP3763383A1 (en) 2013-12-16 2021-01-13 Massachusetts Institute Of Technology Micromolded or 3-d printed pulsatile release vaccine formulations
DK3082902T3 (da) * 2013-12-19 2019-12-16 Medtronic Minimed Inc Kropsbåret injektor og anvendelsesmetode
GB201401133D0 (en) * 2014-01-23 2014-03-12 Renephra Ltd Fluid extraction device, applicator device and associated methods
WO2015119906A1 (en) 2014-02-05 2015-08-13 Amgen Inc. Drug delivery system with electromagnetic field generator
GB201402261D0 (en) 2014-02-10 2014-03-26 Owen Mumford Ltd Injector apparatus
FI3834824T3 (fi) 2014-03-28 2025-12-05 Univ Duke Estrogeenireseptoripositiivisen rintasyövän hoito selektiivisellä estrogeenireseptorin modulaattorilla
RU2633228C1 (ru) * 2014-04-30 2017-10-11 Кимберли-Кларк Ворлдвайд, Инк. Картридж для подачи текучей среды в устройство трансдермальной доставки лекарств (варианты)
MX384280B (es) * 2014-04-30 2025-03-14 Vivasor Inc Metodo y aparato de administracion transdermica de medicamentos.
MX376608B (es) * 2014-04-30 2025-03-04 Vivasor Inc Porcion del receptaculo de un aparato y metodo de administracion transdermica de medicamentos.
CN104056346B (zh) * 2014-06-16 2017-04-26 游学秋 异平面微针阵列及其制作方法
JPWO2016006409A1 (ja) 2014-07-09 2017-04-27 凸版印刷株式会社 液剤注入装置
CN104117138A (zh) * 2014-07-24 2014-10-29 河南科技大学 一种超声微针复合经皮给药装置
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
WO2016072060A1 (ja) 2014-11-05 2016-05-12 凸版印刷株式会社 マイクロニードルセット
US10010708B2 (en) * 2014-12-20 2018-07-03 Esthetic Education LLC Microneedle cartridge and nosecone assembly
EP3037124A1 (en) 2014-12-22 2016-06-29 Universite Libre De Bruxelles Drug delivery device with microneedles
ES2885923T3 (es) * 2015-01-21 2021-12-15 Kindeva Drug Delivery Lp Conjunto de microagujas
JP2018502927A (ja) 2015-01-27 2018-02-01 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルワクチンパッチ用ミョウバン含有コーティング製剤
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
CN107206220A (zh) 2015-02-16 2017-09-26 凸版印刷株式会社 微针
CN112545886A (zh) 2015-03-10 2021-03-26 里珍纳龙药品有限公司 无菌刺穿系统和方法
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
CN107580489B (zh) 2015-03-26 2020-10-16 因内博注射剂公司 加压气体驱动的药剂转移和再悬浮设备和方法
US10893865B2 (en) 2015-04-13 2021-01-19 Mayo Foundation For Medical Education And Research Magnetic wound closure systems
MX393599B (es) 2015-04-29 2025-03-19 Radius Pharmaceuticals Inc Rad1901 para usarse en el tratamiento de cancer en sujetos con cancer positivo a receptor de estrogeno alfa resistente a farmaco
US11207465B2 (en) 2015-06-04 2021-12-28 West Pharma. Services Il. Ltd. Cartridge insertion for drug delivery device
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
CN108430536B (zh) 2015-10-09 2022-04-08 西医药服务以色列分公司 填充定制注射筒的方法
US10518071B2 (en) * 2015-12-29 2019-12-31 Gajanan Kulkarni Transdermal microneedle drug delivery device and method
US11311674B2 (en) 2016-01-21 2022-04-26 West Pharma. Services IL, Ltd. Medicament delivery device comprising a visual indicator
EP3405227B1 (en) * 2016-01-21 2020-06-17 West Pharma. Services Il, Ltd. Force containment in an automatic injector
JP6542481B2 (ja) 2016-01-21 2019-07-10 ウェスト ファーマ サービシーズ イスラエル リミテッド システム
US11389597B2 (en) 2016-03-16 2022-07-19 West Pharma. Services IL, Ltd. Staged telescopic screw assembly having different visual indicators
GB2552193A (en) * 2016-07-13 2018-01-17 Ndm Technologies Ltd Improvements in or relating to transdermal delivery
CN109562229B (zh) 2016-08-01 2021-07-13 西医药服务以色列有限公司 抗旋转药筒销
US11730892B2 (en) 2016-08-01 2023-08-22 West Pharma. Services IL, Ltd. Partial door closure prevention spring
WO2018029520A1 (en) 2016-08-08 2018-02-15 Unitract Syringe Pty Ltd Drug delivery device and method for connecting a fluid flowpath
CN106362250B (zh) * 2016-09-18 2021-03-05 电子科技大学 微型阵列注射器
WO2018060024A1 (en) 2016-09-27 2018-04-05 Sanofi-Aventis Deutschland Gmbh A medicament delivery device
CN107913460B (zh) * 2016-10-10 2021-06-22 苏州纳通生物纳米技术有限公司 一种液体定量输送系统
CN107913459A (zh) * 2016-10-10 2018-04-17 苏州纳通生物纳米技术有限公司 一种液体定量输送装置
EP3315156A1 (en) * 2016-11-01 2018-05-02 Sanofi-Aventis Deutschland GmbH Medicament delivery device
AU2017373857A1 (en) * 2016-12-05 2019-06-13 Morningside Venture Investments Limited Transdermal drug delivery devices and methods
USD819197S1 (en) 2016-12-16 2018-05-29 Kimberly-Clark Worldwide, Inc. Fluid delivery apparatus
AU2017376502B2 (en) 2016-12-16 2023-10-05 Vivasor, Inc. Method for administering a medicament suitable for treating a migraine or cluster headache
WO2018111616A1 (en) 2016-12-16 2018-06-21 Kimberly-Clark Worldwide, Inc. Application device for a fluid delivery apparatus and method of use
CN114681787A (zh) 2016-12-16 2022-07-01 索伦托治疗有限公司 具有控制器组件的流体递送装置及其使用方法
USD836774S1 (en) 2016-12-16 2018-12-25 Sorrento Therapeutics, Inc. Cartridge for a fluid delivery apparatus
EP3338832A1 (en) * 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medicament delivery device
KR102881465B1 (ko) 2017-01-05 2025-11-04 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 経皮薬剤送達の装置及び方法
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
CN115025327B (zh) 2017-05-05 2024-06-28 里珍纳龙药品有限公司 自动注射器和相关使用方法
JP6921997B2 (ja) 2017-05-30 2021-08-18 ウェスト ファーマ サービシーズ イスラエル リミテッド ウェアラブル注射器のモジュラ駆動トレイン
JP6979119B2 (ja) * 2017-08-10 2021-12-08 ウェスト ファーマ サービシーズ イスラエル リミテッド 注射器の遅延式カートリッジ穿孔機構
WO2019077519A1 (en) 2017-10-17 2019-04-25 3M Innovative Properties Company APPLICATOR FOR APPLYING A SKIN INJECTION CHIP
DE102017223505A1 (de) 2017-12-21 2019-06-27 Vetter Pharma-Fertigung GmbH & Co. KG Behälter für medizinische Flüssigkeiten und Verfahren zum Befüllen eines solchen Behälters
CN111683703B (zh) 2017-12-22 2022-11-18 西氏医药包装(以色列)有限公司 适用于不同尺寸的药筒的注射器
US11058605B2 (en) 2018-03-08 2021-07-13 Flex Ltd. Sterilization fluid path with barrier removal
CN112218669B (zh) * 2018-04-11 2024-03-05 赛诺菲 药物递送装置
US20210030963A1 (en) * 2018-04-11 2021-02-04 Sanofi Drug Delivery Device
US11690799B2 (en) 2018-04-19 2023-07-04 Lts Lohmann Therapie-Systeme Ag Microneedle system for applying interferon
WO2019220320A1 (en) 2018-05-16 2019-11-21 3M Innovative Properties Company Microneedle biosensor
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl
CN109568711B (zh) * 2018-11-01 2021-01-01 江苏爱朋医疗科技股份有限公司 输液管的自锁装置
CA3119992A1 (en) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
WO2020143987A1 (en) * 2019-01-07 2020-07-16 Shl Medical Ag Medicament delivery device
DE102019200557A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
KR20210127961A (ko) 2019-02-12 2021-10-25 래디어스 파마슈티컬스, 인코포레이티드 방법 및 화합물
EP3958946A4 (en) * 2019-04-20 2023-05-03 Biolark, Inc. INFUSION SET WITH REDUCED PATIENT PAIN
WO2020219388A1 (en) * 2019-04-20 2020-10-29 Biolark. Inc. An infusion set with full insertion and removal action
CA3178260A1 (en) 2020-05-13 2021-11-18 Massachusetts Institute Of Technology Compositions of polymeric microdevices and their use in cancer immunotherapy
CA3182778A1 (en) * 2020-06-17 2021-12-23 Biolinq, Inc. Devices and methods for application of microneedle arrays
CA3190784A1 (en) * 2020-08-03 2022-02-10 Qulab Medical Ltd. Minimally-invasive monitoring patch
EP4247457B1 (en) * 2020-11-19 2025-12-24 Becton, Dickinson and Company Drug delivery device with container holder
USD920500S1 (en) * 2020-12-14 2021-05-25 Xianlin He Microneedle instrument
US11389376B2 (en) 2020-12-21 2022-07-19 Mediccene Inc. Wearable intravenous fluid delivery system
JP7734362B2 (ja) * 2021-01-16 2025-09-05 シンクランド株式会社 アプリケータ及びアプリケータ用カートリッジ
MX2023010227A (es) * 2021-03-01 2024-02-27 Deka Products Lp Aparatos, sistemas y métodos dispensadores de agente médico.
US12161832B2 (en) 2021-03-01 2024-12-10 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
US12357804B2 (en) 2021-03-01 2025-07-15 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12029562B2 (en) 2021-04-14 2024-07-09 Satio, Inc. Dermal patch system
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
SE545876C2 (en) 2021-09-28 2024-02-27 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
USD1057153S1 (en) 2022-04-29 2025-01-07 Biolinq Incorporated Microneedle array sensor applicator device
AU2023298288A1 (en) * 2022-06-27 2025-01-30 Nutromics Technology Pty Ltd Extended wear microneedle apparatus
AU2023371939A1 (en) 2022-11-05 2025-05-22 Kindeva Drug Delivery L.P. Microneedle array applicator and system
AU2023395786A1 (en) 2022-12-16 2025-07-31 Kindeva Drug Delivery L.P. Drug delivery device
WO2024145424A1 (en) * 2022-12-28 2024-07-04 Satio, Inc. Dermal patch for delivering a pharmaceutical
JP7738215B1 (ja) * 2024-01-29 2025-09-11 久光製薬株式会社 アプリケータ
WO2025164447A1 (ja) * 2024-01-29 2025-08-07 久光製薬株式会社 アプリケータ
WO2025164446A1 (ja) * 2024-01-29 2025-08-07 久光製薬株式会社 アプリケータ

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2814987C2 (de) * 1978-04-07 1980-02-14 Erwin Noll Tätowierzange zum Kennzeichnen der Ohren von Tieren
US4755173A (en) 1986-02-25 1988-07-05 Pacesetter Infusion, Ltd. Soft cannula subcutaneous injection set
US5176662A (en) 1990-08-23 1993-01-05 Minimed Technologies, Ltd. Subcutaneous injection set with improved cannula mounting arrangement
US5257980A (en) 1993-04-05 1993-11-02 Minimed Technologies, Ltd. Subcutaneous injection set with crimp-free soft cannula
CA2132277C (en) * 1993-10-22 2005-05-10 Giorgio Cirelli Injection device
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US6607509B2 (en) 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
DE60138411D1 (de) 2000-10-13 2009-05-28 Alza Corp Vorrichtung und verfahren zum durchstechen der haut mit micronadeln
ATE298528T1 (de) 2000-10-13 2005-07-15 Alza Corp Mikroklingeanordungsaufprallapplikator
AU2002333554C1 (en) 2001-09-12 2008-12-11 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
US6689100B2 (en) 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6945952B2 (en) 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
ES2720098T3 (es) 2002-07-22 2019-07-17 Becton Dickinson Co Dispositivo de infusión similar a un parche
WO2004011065A1 (en) 2002-07-31 2004-02-05 Alza Corporation Injection device providing automatic needle retraction
ATE331542T1 (de) * 2002-08-29 2006-07-15 Novo Nordisk As Injektionsvorrichtung mit frontladung
AU2003278798A1 (en) * 2002-09-12 2004-04-30 Children's Hospital Medical Center Method and device for painless injection of medication
US6896666B2 (en) * 2002-11-08 2005-05-24 Kochamba Family Trust Cutaneous injection delivery under suction
US7252651B2 (en) * 2003-01-07 2007-08-07 Becton, Dickinson And Company Disposable injection device
CA2523267C (en) 2003-04-23 2013-09-03 Biovalve Technologies, Inc. Hydraulically actuated pump for long duration medicament administration
US6926694B2 (en) 2003-05-09 2005-08-09 Medsolve Technologies, Llc Apparatus and method for delivery of therapeutic and/or diagnostic agents
ES2822181T3 (es) * 2003-08-12 2021-04-29 Becton Dickinson Co Dispositivo de infusión a modo de parche
EP1680154B1 (en) 2003-10-31 2012-01-04 ALZA Corporation Self-actuating applicator for microprojection array
US7753879B2 (en) 2004-01-29 2010-07-13 M2 Group Holdings, Inc. Disposable medicine dispensing device
EP1773444B1 (en) 2004-06-10 2017-09-20 3M Innovative Properties Company Patch application device and kit
EP1904158B1 (en) * 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
AU2006261898B2 (en) 2005-06-27 2011-11-03 3M Innovative Properties Company Microneedle array applicator device
JP4963849B2 (ja) * 2006-03-13 2012-06-27 シスメックス株式会社 微細孔形成システム
JP2008154849A (ja) * 2006-12-25 2008-07-10 Ritsumeikan 注入装置
EP2150297A1 (en) * 2007-04-30 2010-02-10 Medtronic MiniMed, Inc. Needle inserting and fluid flow connection for infusion medium delivery system
KR20190064676A (ko) 2008-11-18 2019-06-10 쓰리엠 이노베이티브 프로퍼티즈 컴파니 중공 마이크로니들 어레이
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US10800040B1 (en) 2017-12-14 2020-10-13 Amazon Technologies, Inc. Simulation-real world feedback loop for learning robotic control policies

Also Published As

Publication number Publication date
RU2012102688A (ru) 2013-09-10
ES2661063T3 (es) 2018-03-27
CN102497909A (zh) 2012-06-13
AU2010276511B2 (en) 2013-09-19
US10010706B2 (en) 2018-07-03
WO2011014514A8 (en) 2011-09-15
CA2769102C (en) 2017-09-19
BR112012001685B1 (pt) 2020-11-03
EP2459267B1 (en) 2017-12-20
BR112012001685A2 (pt) 2017-06-13
CN102497909B (zh) 2014-10-29
RU2508135C2 (ru) 2014-02-27
WO2011014514A1 (en) 2011-02-03
EP3354312A1 (en) 2018-08-01
EP2459267A1 (en) 2012-06-06
AU2010276511A1 (en) 2012-02-16
BR112012001685B8 (pt) 2021-06-22
JP2013500773A (ja) 2013-01-10
KR101712226B1 (ko) 2017-03-03
KR20120039733A (ko) 2012-04-25
US20180304063A1 (en) 2018-10-25
US11103685B2 (en) 2021-08-31
US20120123387A1 (en) 2012-05-17
CA2769102A1 (en) 2011-02-03

Similar Documents

Publication Publication Date Title
JP5702384B2 (ja) 中空マイクロニードルアレイ
JP6411888B2 (ja) 中空マイクロニードルアレイのための送達システム
CN104870049B (zh) 粘合剂组件和包括该粘合剂组件的微针注入设备
DK1523355T3 (en) PLASTER-LIKE INFUSION DEVICE
JP5450568B2 (ja) パッチ様注入装置
CN110958893B (zh) 药物输送装置

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130726

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130726

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140509

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140513

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140811

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150120

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150219

R150 Certificate of patent or registration of utility model

Ref document number: 5702384

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: R3D02

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees