JP5684130B2 - 組換えベクター - Google Patents

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JP5684130B2
JP5684130B2 JP2011529292A JP2011529292A JP5684130B2 JP 5684130 B2 JP5684130 B2 JP 5684130B2 JP 2011529292 A JP2011529292 A JP 2011529292A JP 2011529292 A JP2011529292 A JP 2011529292A JP 5684130 B2 JP5684130 B2 JP 5684130B2
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sequence
retrovirus
polynucleotide
vector
cells
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Japanese (ja)
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JP2012503987A5 (https=
JP2012503987A (ja
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グルーバー，ハリー，イー．
ジョリー，ダグラス
ペレス，オマール
ログ，クリストファー，アール．
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トカジェン インコーポレーテッド
トカジェン インコーポレーテッド
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
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    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
    • C12Y305/04001—Cytosine deaminase (3.5.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C12N2310/141—MicroRNAs, miRNAs
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/10—Vectors comprising a special translation-regulating system regulates levels of translation
    • C12N2840/102—Vectors comprising a special translation-regulating system regulates levels of translation inhibiting translation
    • C—CHEMISTRY; METALLURGY
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011529292A 2008-09-26 2009-09-26 組換えベクター Expired - Fee Related JP5684130B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10066608P 2008-09-26 2008-09-26
US61/100,666 2008-09-26
US12061808P 2008-12-08 2008-12-08
US61/120,618 2008-12-08
US18682309P 2009-06-13 2009-06-13
US61/186,823 2009-06-13
PCT/US2009/058512 WO2010036986A2 (en) 2008-09-26 2009-09-26 Recombinant vectors

Related Child Applications (1)

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JP2015004923A Division JP5992548B2 (ja) 2008-09-26 2015-01-14 組換えベクター

Publications (3)

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JP2012503987A JP2012503987A (ja) 2012-02-16
JP2012503987A5 JP2012503987A5 (https=) 2012-11-15
JP5684130B2 true JP5684130B2 (ja) 2015-03-11

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ID=42060421

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JP2011529292A Expired - Fee Related JP5684130B2 (ja) 2008-09-26 2009-09-26 組換えベクター
JP2011529291A Expired - Fee Related JP5771147B2 (ja) 2008-09-26 2009-09-26 遺伝子治療ベクターおよびシトシンデアミナーゼ
JP2015004923A Expired - Fee Related JP5992548B2 (ja) 2008-09-26 2015-01-14 組換えベクター
JP2015097980A Expired - Fee Related JP6062485B2 (ja) 2008-09-26 2015-05-13 遺伝子治療ベクターおよびシトシンデアミナーゼ
JP2016159893A Expired - Fee Related JP6523224B2 (ja) 2008-09-26 2016-08-17 組換えベクター
JP2019086133A Pending JP2019141088A (ja) 2008-09-26 2019-04-26 組換えベクター

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JP2011529291A Expired - Fee Related JP5771147B2 (ja) 2008-09-26 2009-09-26 遺伝子治療ベクターおよびシトシンデアミナーゼ
JP2015004923A Expired - Fee Related JP5992548B2 (ja) 2008-09-26 2015-01-14 組換えベクター
JP2015097980A Expired - Fee Related JP6062485B2 (ja) 2008-09-26 2015-05-13 遺伝子治療ベクターおよびシトシンデアミナーゼ
JP2016159893A Expired - Fee Related JP6523224B2 (ja) 2008-09-26 2016-08-17 組換えベクター
JP2019086133A Pending JP2019141088A (ja) 2008-09-26 2019-04-26 組換えベクター

Country Status (18)

Country Link
US (3) US8722867B2 (https=)
EP (4) EP2346995B1 (https=)
JP (6) JP5684130B2 (https=)
KR (3) KR101870056B1 (https=)
CN (4) CN102227503B (https=)
AU (1) AU2009303690B2 (https=)
BR (1) BRPI0919113A2 (https=)
CA (1) CA2738472A1 (https=)
CO (1) CO6362050A2 (https=)
DK (1) DK2346995T3 (https=)
EA (2) EA201790824A3 (https=)
ES (2) ES2706899T3 (https=)
IL (3) IL211847A (https=)
MX (3) MX2011003039A (https=)
MY (1) MY156333A (https=)
NZ (1) NZ592070A (https=)
WO (2) WO2010045002A2 (https=)
ZA (1) ZA201102115B (https=)

Cited By (1)

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JP2015119712A (ja) * 2008-09-26 2015-07-02 トカジェン インコーポレーテッド 組換えベクター

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