JP5681182B2 - 腫瘍および炎症性疾患の処置のためのアミノピリジン誘導体 - Google Patents

腫瘍および炎症性疾患の処置のためのアミノピリジン誘導体 Download PDF

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JP5681182B2
JP5681182B2 JP2012519900A JP2012519900A JP5681182B2 JP 5681182 B2 JP5681182 B2 JP 5681182B2 JP 2012519900 A JP2012519900 A JP 2012519900A JP 2012519900 A JP2012519900 A JP 2012519900A JP 5681182 B2 JP5681182 B2 JP 5681182B2
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mmol
amino
disease
compounds
methyl
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JP2012532899A (ja
JP2012532899A5 (enExample
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ミシェル，カルデリーニ
ヴッヘラー−プリートカー，マルガリータ
ウルリッヒ グレードラー、
ウルリッヒ グレードラー、
エスダール，クリスティーナ
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Merck Patent GmbH
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JP2012519900A 2009-07-15 2010-06-17 腫瘍および炎症性疾患の処置のためのアミノピリジン誘導体 Expired - Fee Related JP5681182B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009033208A DE102009033208A1 (de) 2009-07-15 2009-07-15 Aminopyridinderivate
DE102009033208.1 2009-07-15
PCT/EP2010/003659 WO2011006567A1 (de) 2009-07-15 2010-06-17 Aminopyridinderivate zur behandlung von tumoren und entzündungskrankheiten

Publications (3)

Publication Number Publication Date
JP2012532899A JP2012532899A (ja) 2012-12-20
JP2012532899A5 JP2012532899A5 (enExample) 2013-08-29
JP5681182B2 true JP5681182B2 (ja) 2015-03-04

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US (1) US8648201B2 (enExample)
EP (1) EP2454253B1 (enExample)
JP (1) JP5681182B2 (enExample)
CN (1) CN102471317B (enExample)
AR (1) AR077567A1 (enExample)
AU (1) AU2010272920B2 (enExample)
CA (1) CA2768169C (enExample)
DE (1) DE102009033208A1 (enExample)
ES (1) ES2534095T3 (enExample)
IL (1) IL217467A (enExample)
WO (1) WO2011006567A1 (enExample)

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JP5690839B2 (ja) * 2009-12-04 2015-03-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ロイコトリエン産生のベンゾイミダゾール阻害薬
AU2012225805B2 (en) * 2011-03-04 2017-03-02 Lexicon Pharmaceuticals, Inc. MST1 kinase inhibitors and methods of their use
WO2013019682A1 (en) * 2011-07-29 2013-02-07 Tempero Pharmaceuticals, Inc. Compounds and methods
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WO2014058691A1 (en) * 2012-10-08 2014-04-17 Merck Sharp & Dohme Corp. Inhibitors of irak4 activity
EP2903617B1 (en) 2012-10-08 2019-01-30 Merck Sharp & Dohme Corp. Inhibitors of irak4 activity
EP3019171B1 (en) 2013-07-11 2018-09-05 Merck Sharp & Dohme Corp. Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
DK3107901T3 (da) 2014-02-19 2020-06-22 Piramal Entpr Ltd Forbindelser til brug som gpr120 agonister
CA2955919A1 (en) 2014-07-25 2016-01-28 Piramal Enterprises Limited Substituted phenyl alkanoic acid compounds as gpr120 agonists and uses thereof
EP3191463B1 (en) * 2014-09-11 2019-10-30 Piramal Enterprises Limited Fused heterocyclic compounds as gpr120 agonists
US9359336B2 (en) 2014-10-09 2016-06-07 Allergan, Inc. Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors
WO2017015152A1 (en) 2015-07-17 2017-01-26 Memorial Sloan-Kettering Cancer Center Combination therapy using pdk1 and pi3k inhibitors
JOP20180011A1 (ar) 2017-02-16 2019-01-30 Gilead Sciences Inc مشتقات بيرولو [1، 2-b]بيريدازين
TWI898556B (zh) 2018-07-13 2025-09-21 美商基利科學股份有限公司 吡咯并[1,2-b]嗒衍生物
CN112457308B (zh) * 2019-09-09 2024-01-02 上海长森药业有限公司 新型三环芳香杂环化合物，及其制备方法、药物组合物和应用
WO2022076975A1 (en) 2020-10-05 2022-04-14 Enliven Therapeutics, Inc. 5- and 6-azaindole compounds for inhibition of bcr-abl tyrosine kinases
WO2023166351A1 (zh) * 2022-03-02 2023-09-07 杭州百诚医药科技股份有限公司 组胺h3受体抑制剂及其医药用途

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IL217467A0 (en) 2012-03-01
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AU2010272920A1 (en) 2012-03-08
US20120115861A1 (en) 2012-05-10
CA2768169A1 (en) 2011-01-20
EP2454253A1 (de) 2012-05-23
JP2012532899A (ja) 2012-12-20
CA2768169C (en) 2017-06-13
US8648201B2 (en) 2014-02-11
AR077567A1 (es) 2011-09-07
CN102471317A (zh) 2012-05-23
WO2011006567A1 (de) 2011-01-20
ES2534095T3 (es) 2015-04-17
DE102009033208A1 (de) 2011-01-20
CN102471317B (zh) 2014-02-26
AU2010272920B2 (en) 2016-05-05

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