AU2010272920B2 - Aminopyridine derivatives for treating tumors and inflammatory diseases - Google Patents

Aminopyridine derivatives for treating tumors and inflammatory diseases Download PDF

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Publication number
AU2010272920B2
AU2010272920B2 AU2010272920A AU2010272920A AU2010272920B2 AU 2010272920 B2 AU2010272920 B2 AU 2010272920B2 AU 2010272920 A AU2010272920 A AU 2010272920A AU 2010272920 A AU2010272920 A AU 2010272920A AU 2010272920 B2 AU2010272920 B2 AU 2010272920B2
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Prior art keywords
pyridin
pyrazol
benzimidazol
methyl
amino
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Ceased
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AU2010272920A
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AU2010272920A1 (en
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Michel Calderini
Christina Esdar
Ulrich Graedler
Margarita Wucherer-Plietker
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Merck Patent GmbH
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Merck Patent GmbH
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  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
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  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Vascular Medicine (AREA)
AU2010272920A 2009-07-15 2010-06-17 Aminopyridine derivatives for treating tumors and inflammatory diseases Ceased AU2010272920B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009033208A DE102009033208A1 (de) 2009-07-15 2009-07-15 Aminopyridinderivate
DE102009033208.1 2009-07-15
PCT/EP2010/003659 WO2011006567A1 (de) 2009-07-15 2010-06-17 Aminopyridinderivate zur behandlung von tumoren und entzündungskrankheiten

Publications (2)

Publication Number Publication Date
AU2010272920A1 AU2010272920A1 (en) 2012-03-08
AU2010272920B2 true AU2010272920B2 (en) 2016-05-05

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AU2010272920A Ceased AU2010272920B2 (en) 2009-07-15 2010-06-17 Aminopyridine derivatives for treating tumors and inflammatory diseases

Country Status (11)

Country Link
US (1) US8648201B2 (enExample)
EP (1) EP2454253B1 (enExample)
JP (1) JP5681182B2 (enExample)
CN (1) CN102471317B (enExample)
AR (1) AR077567A1 (enExample)
AU (1) AU2010272920B2 (enExample)
CA (1) CA2768169C (enExample)
DE (1) DE102009033208A1 (enExample)
ES (1) ES2534095T3 (enExample)
IL (1) IL217467A (enExample)
WO (1) WO2011006567A1 (enExample)

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JP5690839B2 (ja) * 2009-12-04 2015-03-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ロイコトリエン産生のベンゾイミダゾール阻害薬
KR20140014205A (ko) * 2011-03-04 2014-02-05 렉시컨 파마슈티컬스 인코퍼레이티드 Mst1 키나제 억제제 및 그의 사용 방법
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BR112015000399A2 (pt) * 2012-07-10 2017-06-27 Ares Trading Sa derivados de pirazolil pirimidina
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WO2014058691A1 (en) * 2012-10-08 2014-04-17 Merck Sharp & Dohme Corp. Inhibitors of irak4 activity
US20160166576A1 (en) 2013-07-11 2016-06-16 Merck Sharp & Dohme Corp. Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
CA2935897C (en) 2014-02-19 2018-07-03 Piramal Enterprises Limited Compounds for use as gpr120 agonists
CA2955919A1 (en) 2014-07-25 2016-01-28 Piramal Enterprises Limited Substituted phenyl alkanoic acid compounds as gpr120 agonists and uses thereof
EP3191463B1 (en) * 2014-09-11 2019-10-30 Piramal Enterprises Limited Fused heterocyclic compounds as gpr120 agonists
US9359336B2 (en) 2014-10-09 2016-06-07 Allergan, Inc. Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors
EP3325100A4 (en) 2015-07-17 2019-02-20 Memorial Sloan-Kettering Cancer Center COMBINATION THERAPY WITH PDK1 AND PI3K INHIBITORS
TW202340194A (zh) 2017-02-16 2023-10-16 美商基利科學股份有限公司 吡咯并[1,2-b]嗒𠯤衍生物
TWI721483B (zh) 2018-07-13 2021-03-11 美商基利科學股份有限公司 吡咯并[1,2-b]嗒𠯤衍生物
CN112457308B (zh) * 2019-09-09 2024-01-02 上海长森药业有限公司 新型三环芳香杂环化合物，及其制备方法、药物组合物和应用
CA3196620A1 (en) 2020-10-05 2022-04-14 Enliven Therapeutics, Inc. 5- and 6-azaindole compounds for inhibition of bcr-abl tyrosine kinases
KR20250016079A (ko) * 2022-03-02 2025-02-03 항저우 바이오-신세리티 파마-테크 컴퍼니 리미티드 히스타민 h3 수용체 길항제 및 이의 약학적 용도
WO2025247379A1 (zh) * 2024-05-30 2025-12-04 深圳微芯生物科技股份有限公司 一种苯并咪唑类化合物、其制备方法及应用

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JP5681182B2 (ja) 2015-03-04
CN102471317B (zh) 2014-02-26
EP2454253B1 (de) 2015-01-21
WO2011006567A1 (de) 2011-01-20
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IL217467A0 (en) 2012-03-01
CN102471317A (zh) 2012-05-23
AR077567A1 (es) 2011-09-07
US20120115861A1 (en) 2012-05-10
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