JP5671347B2 - アドレナリン受容体のα１ループ２またはβ２ループ１上のエピトープを認識する抗体に対して結合親和性を有するペプチド - Google Patents
アドレナリン受容体のα１ループ２またはβ２ループ１上のエピトープを認識する抗体に対して結合親和性を有するペプチド Download PDFInfo
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1787—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
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- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08100510.0 | 2008-01-15 | ||
| EP08100510A EP2080519A1 (en) | 2008-01-15 | 2008-01-15 | Peptides having binding affinity to an antibody which recognizes an epitope on an alpha1 loop 2 or beta 2 loop 1 of an adrenoreceptor |
| PCT/EP2009/050446 WO2009090227A2 (en) | 2008-01-15 | 2009-01-15 | PEPTIDES HAVING BINDING AFFINITY TO AN ANTIBODY WHICH RECOGNIZES AN EPITOPE ON AN α1 LOOP 2 OR β2 LOOP 1 OF AN ADRENORECEPTOR |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011518113A JP2011518113A (ja) | 2011-06-23 |
| JP2011518113A5 JP2011518113A5 (enExample) | 2014-02-20 |
| JP5671347B2 true JP5671347B2 (ja) | 2015-02-18 |
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| JP2010542631A Expired - Fee Related JP5671347B2 (ja) | 2008-01-15 | 2009-01-15 | アドレナリン受容体のα１ループ２またはβ２ループ１上のエピトープを認識する抗体に対して結合親和性を有するペプチド |
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|---|---|
| US (2) | US8455442B2 (enExample) |
| EP (2) | EP2080519A1 (enExample) |
| JP (1) | JP5671347B2 (enExample) |
| ES (1) | ES2639573T3 (enExample) |
| WO (1) | WO2009090227A2 (enExample) |
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| EP2497828A1 (en) | 2011-03-07 | 2012-09-12 | Charité - Universitätsmedizin Berlin | Use of aptamers in therapy and/or diagnosis of autoimmune diseases |
| US20140199318A1 (en) | 2011-08-12 | 2014-07-17 | Max-Del-Bruck-Centrum Fur Molekulare Medizin | Agonistic autoantibodies to the alpha1-adrenergic receptor and the beta2-adrenergic receptor in alzheimer's and vascular dementia |
| KR20150032265A (ko) * | 2012-06-26 | 2015-03-25 | 에프. 호프만-라 로슈 아게 | 세포 침투성 펩티드 및 세포 침투성 펩티드의 식별 방법 |
| JP2017515799A (ja) * | 2014-04-03 | 2017-06-15 | オウ テルヴィスリク ピーマ バイオテウノロジーテ アレンダスケスクス | コレステロール低下剤およびクロストリジウム・ディフィシレに対する抗微生物剤としてのラクトバチルス・プランタルムＩｎｄｕｃｉａ株ＤＳＭ２１３７９ |
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| AU677968B2 (en) * | 1992-09-25 | 1997-05-15 | H. Lundbeck A/S | DNA encoding human alpha 1 adrenergic receptors and uses thereof |
| JP2003514772A (ja) * | 1999-09-21 | 2003-04-22 | アフィーナ イミュンテヒニク ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｄｃｍを引き起こす自己抗体に対するペプチド |
| WO2002038592A2 (de) * | 2000-11-08 | 2002-05-16 | Affina Immuntechnik Gmbh | Peptide, deren herstellung und verwendung zur bindung von immunglobulinen |
| US6451547B1 (en) * | 2001-04-25 | 2002-09-17 | Syn X Pharma | Process for differential diagnosis of Alzheimer's dementia and device therefor |
| US20020172676A1 (en) * | 2001-05-16 | 2002-11-21 | George Jackowski | Method of treatment of alzheimer's disease and device therefor |
| WO2004051280A2 (de) * | 2002-11-29 | 2004-06-17 | Max-Delbrück-Centrum für Molekulare Medizin | Bestimmung agonistischer autoantikörper |
| JP2008537961A (ja) * | 2005-04-15 | 2008-10-02 | ボード、オブ、トラスティーズ、オブ、ミシガン、ステイト、ユニバーシティ | Ｇｐｃｒモジュレーター |
| EP1832600A1 (en) * | 2006-03-09 | 2007-09-12 | Max-Delbrück-Centrum Für Molekulare Medizin | Peptides against autoantibodies associated with glaucoma and use of these peptides |
| WO2008151847A1 (en) | 2007-06-13 | 2008-12-18 | Max-Delbrück-Centrum für Molekulare Medizin | Autoantibody binding peptides and their use for the treatment of vascular diseases |
| WO2009132283A2 (en) * | 2008-04-24 | 2009-10-29 | University Of Miami | Method for treating autoimmune disorders |
| US8216786B2 (en) * | 2008-07-09 | 2012-07-10 | Celera Corporation | Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof |
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- 2009-01-15 EP EP09702027.5A patent/EP2244718B1/en active Active
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| ES2639573T3 (es) | 2017-10-27 |
| US20110104226A1 (en) | 2011-05-05 |
| EP2244718A2 (en) | 2010-11-03 |
| US20130302292A1 (en) | 2013-11-14 |
| JP2011518113A (ja) | 2011-06-23 |
| EP2244718B1 (en) | 2017-06-07 |
| WO2009090227A2 (en) | 2009-07-23 |
| EP2080519A1 (en) | 2009-07-22 |
| US8455442B2 (en) | 2013-06-04 |
| WO2009090227A3 (en) | 2010-02-04 |
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