JP5656474B2 - 脂肪族光学活性フルオロアルコールの製造方法 - Google Patents
脂肪族光学活性フルオロアルコールの製造方法 Download PDFInfo
- Publication number
- JP5656474B2 JP5656474B2 JP2010146219A JP2010146219A JP5656474B2 JP 5656474 B2 JP5656474 B2 JP 5656474B2 JP 2010146219 A JP2010146219 A JP 2010146219A JP 2010146219 A JP2010146219 A JP 2010146219A JP 5656474 B2 JP5656474 B2 JP 5656474B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- substituent
- alkyl group
- reaction
- fluorine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010146219A JP5656474B2 (ja) | 2010-06-28 | 2010-06-28 | 脂肪族光学活性フルオロアルコールの製造方法 |
| EP11005179.4A EP2399895B1 (en) | 2010-06-28 | 2011-06-27 | Process for producing optically active aliphatic fluoroalcohol |
| US13/170,347 US8558033B2 (en) | 2010-06-28 | 2011-06-28 | Process for producing optically active aliphatic fluoroalcohol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010146219A JP5656474B2 (ja) | 2010-06-28 | 2010-06-28 | 脂肪族光学活性フルオロアルコールの製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012006888A JP2012006888A (ja) | 2012-01-12 |
| JP2012006888A5 JP2012006888A5 (https=) | 2013-07-18 |
| JP5656474B2 true JP5656474B2 (ja) | 2015-01-21 |
Family
ID=44533673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010146219A Active JP5656474B2 (ja) | 2010-06-28 | 2010-06-28 | 脂肪族光学活性フルオロアルコールの製造方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US8558033B2 (https=) |
| EP (1) | EP2399895B1 (https=) |
| JP (1) | JP5656474B2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104447205A (zh) * | 2014-11-27 | 2015-03-25 | 广东东阳光药业有限公司 | 制备(s)-三氟异丙醇的方法 |
| JP6457841B2 (ja) * | 2015-03-03 | 2019-01-23 | 公立大学法人 富山県立大学 | キラル−1,1−ジフルオロ−2−プロパノールの工業的な製造方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2962668B2 (ja) | 1995-12-06 | 1999-10-12 | 科学技術振興事業団 | 光学活性アルコール類の製造方法 |
| JPH09301929A (ja) | 1996-03-11 | 1997-11-25 | Showa Shell Sekiyu Kk | 応答速度の速い反強誘電性液晶化合物およびそれを含む反強誘電性液晶組成物 |
| GB9706321D0 (en) | 1997-03-26 | 1997-05-14 | Zeneca Ltd | Catalytic hydrogenation |
| JP4425654B2 (ja) * | 2004-02-03 | 2010-03-03 | 高砂香料工業株式会社 | 水溶性遷移金属−ジアミン錯体、及びその製造方法、並びにその用途 |
| JP4621918B2 (ja) * | 2005-12-09 | 2011-02-02 | 国立大学法人 千葉大学 | 新規不斉イリジウム触媒の製造方法とこれらを用いる光学活性β−ヒドロキシ−α−アミノ酸誘導体の製造方法 |
| EP2054363B1 (en) | 2006-07-27 | 2013-04-17 | F. Hoffmann-La Roche AG | Asymmetric hydrogenation of 1,1,1-trifluoroacetone |
| WO2008107334A2 (en) * | 2007-03-05 | 2008-09-12 | F. Hoffmann-La Roche Ag | Process for the synthesis of glyt-1 inhibitors |
| WO2010004957A1 (ja) * | 2008-07-08 | 2010-01-14 | 住友化学株式会社 | キラルなイリジウムアクア錯体およびそれを用いた光学活性ヒドロキシ化合物の製造方法 |
| JP5727127B2 (ja) * | 2009-04-10 | 2015-06-03 | 関東化学株式会社 | 不斉触媒およびこれを用いた光学活性アルコール類の製造方法 |
-
2010
- 2010-06-28 JP JP2010146219A patent/JP5656474B2/ja active Active
-
2011
- 2011-06-27 EP EP11005179.4A patent/EP2399895B1/en not_active Not-in-force
- 2011-06-28 US US13/170,347 patent/US8558033B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8558033B2 (en) | 2013-10-15 |
| JP2012006888A (ja) | 2012-01-12 |
| EP2399895A3 (en) | 2012-10-17 |
| US20110319671A1 (en) | 2011-12-29 |
| EP2399895B1 (en) | 2018-08-08 |
| EP2399895A2 (en) | 2011-12-28 |
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