JP5650642B2 - メチオニンアナログおよびそれらを使用する方法 - Google Patents

メチオニンアナログおよびそれらを使用する方法 Download PDF

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Publication number
JP5650642B2
JP5650642B2 JP2011521364A JP2011521364A JP5650642B2 JP 5650642 B2 JP5650642 B2 JP 5650642B2 JP 2011521364 A JP2011521364 A JP 2011521364A JP 2011521364 A JP2011521364 A JP 2011521364A JP 5650642 B2 JP5650642 B2 JP 5650642B2
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Japan
Prior art keywords
compound
alkyl
optionally substituted
pharmaceutically acceptable
cycloalkyl
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JP2011521364A
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Japanese (ja)
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JP2011529921A5 (https=
JP2011529921A (ja
Inventor
マンスール バッシィリ，
マンスール バッシィリ，
アフサネー ライミ−ラリジャーニ，
アフサネー ライミ−ラリジャーニ，
Original Assignee
バイオキシネス ファーマシューティカルズ， インコーポレイテッド
バイオキシネス ファーマシューティカルズ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011521364A 2008-08-01 2009-07-31 メチオニンアナログおよびそれらを使用する方法 Expired - Fee Related JP5650642B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8555608P 2008-08-01 2008-08-01
US61/085,556 2008-08-01
PCT/US2009/052474 WO2010014943A2 (en) 2008-08-01 2009-07-31 Methionine analogs and methods of using same

Publications (3)

Publication Number Publication Date
JP2011529921A JP2011529921A (ja) 2011-12-15
JP2011529921A5 JP2011529921A5 (https=) 2012-09-13
JP5650642B2 true JP5650642B2 (ja) 2015-01-07

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ID=41414372

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011521364A Expired - Fee Related JP5650642B2 (ja) 2008-08-01 2009-07-31 メチオニンアナログおよびそれらを使用する方法

Country Status (8)

Country Link
US (5) US8580859B2 (https=)
EP (1) EP2326619B1 (https=)
JP (1) JP5650642B2 (https=)
CN (1) CN102171185A (https=)
AU (1) AU2009276343A1 (https=)
CA (1) CA2733390A1 (https=)
IL (1) IL210956A0 (https=)
WO (1) WO2010014943A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2326619B1 (en) 2008-08-01 2019-02-27 Bioxiness Pharmaceuticals, Inc. Methionine analogs and methods of using same
US9200251B1 (en) 2011-03-31 2015-12-01 David Gordon Bermudes Bacterial methionine analogue and methionine synthesis inhibitor anticancer, antiinfective and coronary heart disease protective microcins and methods of treatment therewith
WO2019169029A1 (en) 2018-02-28 2019-09-06 Bioxiness Pharmaceuticals, Inc. Target specific chemotherapeutic agents

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Also Published As

Publication number Publication date
EP2326619A2 (en) 2011-06-01
US20170029369A1 (en) 2017-02-02
WO2010014943A3 (en) 2011-01-13
EP2326619B1 (en) 2019-02-27
US20140142189A1 (en) 2014-05-22
WO2010014943A2 (en) 2010-02-04
CA2733390A1 (en) 2010-02-04
US20110196014A1 (en) 2011-08-11
IL210956A0 (en) 2011-04-28
US9695119B2 (en) 2017-07-04
US20170267632A1 (en) 2017-09-21
US8580859B2 (en) 2013-11-12
CN102171185A (zh) 2011-08-31
JP2011529921A (ja) 2011-12-15
US20150329481A1 (en) 2015-11-19
AU2009276343A1 (en) 2010-02-04

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