CN102171185A - 甲硫氨酸类似物及其使用方法 - Google Patents

甲硫氨酸类似物及其使用方法 Download PDF

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Publication number
CN102171185A
CN102171185A CN2009801390134A CN200980139013A CN102171185A CN 102171185 A CN102171185 A CN 102171185A CN 2009801390134 A CN2009801390134 A CN 2009801390134A CN 200980139013 A CN200980139013 A CN 200980139013A CN 102171185 A CN102171185 A CN 102171185A
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China
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compound
alkyl
optionally substituted
cycloalkyl
moiety
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Pending
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CN2009801390134A
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English (en)
Chinese (zh)
Inventor
曼索尔.巴希里
阿夫萨内.拉希米-拉里贾尼
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Bioxiness Pharmaceuticals Inc
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Bioxiness Pharmaceuticals Inc
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Publication of CN102171185A publication Critical patent/CN102171185A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2009801390134A 2008-08-01 2009-07-31 甲硫氨酸类似物及其使用方法 Pending CN102171185A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8555608P 2008-08-01 2008-08-01
US61/085,556 2008-08-01
PCT/US2009/052474 WO2010014943A2 (en) 2008-08-01 2009-07-31 Methionine analogs and methods of using same

Publications (1)

Publication Number Publication Date
CN102171185A true CN102171185A (zh) 2011-08-31

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ID=41414372

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801390134A Pending CN102171185A (zh) 2008-08-01 2009-07-31 甲硫氨酸类似物及其使用方法

Country Status (8)

Country Link
US (5) US8580859B2 (https=)
EP (1) EP2326619B1 (https=)
JP (1) JP5650642B2 (https=)
CN (1) CN102171185A (https=)
AU (1) AU2009276343A1 (https=)
CA (1) CA2733390A1 (https=)
IL (1) IL210956A0 (https=)
WO (1) WO2010014943A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102171185A (zh) 2008-08-01 2011-08-31 拜奥西尼斯医药股份有限公司 甲硫氨酸类似物及其使用方法
US9200251B1 (en) 2011-03-31 2015-12-01 David Gordon Bermudes Bacterial methionine analogue and methionine synthesis inhibitor anticancer, antiinfective and coronary heart disease protective microcins and methods of treatment therewith
WO2019169029A1 (en) 2018-02-28 2019-09-06 Bioxiness Pharmaceuticals, Inc. Target specific chemotherapeutic agents

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Also Published As

Publication number Publication date
US20110196014A1 (en) 2011-08-11
JP2011529921A (ja) 2011-12-15
EP2326619B1 (en) 2019-02-27
WO2010014943A2 (en) 2010-02-04
IL210956A0 (en) 2011-04-28
WO2010014943A3 (en) 2011-01-13
US20170267632A1 (en) 2017-09-21
US8580859B2 (en) 2013-11-12
US9695119B2 (en) 2017-07-04
US20140142189A1 (en) 2014-05-22
JP5650642B2 (ja) 2015-01-07
EP2326619A2 (en) 2011-06-01
US20170029369A1 (en) 2017-02-02
US20150329481A1 (en) 2015-11-19
AU2009276343A1 (en) 2010-02-04
CA2733390A1 (en) 2010-02-04

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Application publication date: 20110831