JP5637848B2 - 髄膜炎ワクチンの製剤化 - Google Patents
髄膜炎ワクチンの製剤化 Download PDFInfo
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- JP5637848B2 JP5637848B2 JP2010510910A JP2010510910A JP5637848B2 JP 5637848 B2 JP5637848 B2 JP 5637848B2 JP 2010510910 A JP2010510910 A JP 2010510910A JP 2010510910 A JP2010510910 A JP 2010510910A JP 5637848 B2 JP5637848 B2 JP 5637848B2
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- saccharide
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- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- A—HUMAN NECESSITIES
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- A61K2039/70—Multivalent vaccine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US60/933,235 | 2007-06-04 | ||
| PCT/IB2008/002121 WO2008149238A2 (en) | 2007-06-04 | 2008-06-04 | Formulation of meningitis vaccines |
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| JP2010529103A JP2010529103A (ja) | 2010-08-26 |
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Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2304065T3 (es) | 1998-05-01 | 2008-09-01 | Novartis Vaccines And Diagnostics, Inc. | Antigenos y composiciones de neisseria meningitidis. |
| DK2270173T3 (en) | 1999-05-19 | 2016-03-07 | Glaxosmithkline Biolog Sa | Neisserial combination compositions |
| CA2864069A1 (en) | 1999-10-29 | 2001-05-03 | Novartis Vaccines And Diagnostics S.R.L. | Neisserial antigenic peptides |
| MXPA02008313A (es) | 2000-02-28 | 2002-12-09 | Chiron Spa | Expresion hibrida de proteinas de neisseria. |
| EP2279748A1 (en) * | 2000-06-29 | 2011-02-02 | SmithKline Beecham Biologicals S.A. | Multivalent vaccine composition |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| JP2008543907A (ja) * | 2005-06-27 | 2008-12-04 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組成物 |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| DK2200642T3 (da) * | 2007-10-19 | 2012-07-16 | Novartis Ag | Meningococvaccinepræparater |
| AU2009215364B2 (en) | 2008-02-21 | 2014-09-18 | Glaxosmithkline Biologicals S.A. | Meningococcal fHBP polypeptides |
| CA2728344A1 (en) | 2008-06-16 | 2010-01-14 | Academia Sinica | Compositions for inducing immune responses specific to globo h and ssea3 and uses thereof in cancer treatment |
| GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| JP5668049B2 (ja) * | 2009-03-24 | 2015-02-12 | ノバルティス アーゲー | 髄膜炎菌ｈ因子結合タンパク質および肺炎球菌糖結合体の組み合わせ |
| WO2010109323A1 (en) | 2009-03-24 | 2010-09-30 | Novartis Ag | Adjuvanting meningococcal factor h binding protein |
| AU2011268507B2 (en) | 2010-06-25 | 2014-08-14 | Novartis Ag | Combinations of meningococcal factor H binding proteins |
| DK3831406T3 (da) | 2010-08-23 | 2024-06-17 | Wyeth Llc | Stabile formuleringer af Neisseria-Meningitidis-RLP2086-antigener |
| ES2728282T3 (es) | 2010-09-10 | 2019-10-23 | Wyeth Llc | Variantes no lipidadas de antígenos ORF2086 de Neisseria meningitidis |
| US20130273098A1 (en) * | 2010-12-10 | 2013-10-17 | Jeffrey T. Blue | Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions |
| IN2012MU00206A (enExample) * | 2012-01-20 | 2013-08-09 | ||
| CN104159602B (zh) * | 2012-03-08 | 2017-10-24 | 葛兰素史密丝克莱恩生物有限公司 | 加强疫苗的含佐剂制剂 |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| MY198910A (en) | 2012-03-09 | 2023-10-02 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| RU2644340C2 (ru) | 2012-06-14 | 2018-02-08 | Новартис Аг | Вакцины для менингококка серогруппы х |
| JP6446377B2 (ja) | 2013-03-08 | 2018-12-26 | ファイザー・インク | 免疫原性融合ポリペプチド |
| KR20180099912A (ko) | 2013-09-08 | 2018-09-05 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
| EP3270959A1 (en) | 2015-02-19 | 2018-01-24 | Pfizer Inc | Neisseria meningitidis compositions and methods thereof |
| PT3506935T (pt) | 2016-09-02 | 2024-04-01 | Sanofi Pasteur Inc | Vacina contra neisseria meningitidis |
| SG10202111092UA (en) | 2017-01-31 | 2021-11-29 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| KR102871663B1 (ko) | 2019-09-27 | 2025-10-16 | 화이자 인코포레이티드 | 네이세리아 메닌기티디스 조성물 및 그의 방법 |
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| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| PL175595B1 (pl) | 1992-08-31 | 1999-01-29 | North American Vaccine Inc | Antygenowy/immunogenny koniugat do wytwarzania szczepionki przeciwko infekcji N.meningitidis, sposób wytwarzania antygenowego/immunogennego koniugatu oraz szczepionka przeciwko infekcji N.meningitidis |
| US5425946A (en) | 1992-08-31 | 1995-06-20 | North American Vaccine, Inc. | Vaccines against group C Neisseria meningitidis |
| GB9422096D0 (en) * | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
| CA2222455C (en) | 1995-03-22 | 2013-05-28 | Smithkline Beecham Biologicals S.A. | A vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| EP2279748A1 (en) | 2000-06-29 | 2011-02-02 | SmithKline Beecham Biologicals S.A. | Multivalent vaccine composition |
| JP2005504718A (ja) | 2001-01-23 | 2005-02-17 | アヴェンティス パストゥール | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| DK1490409T3 (da) | 2002-03-26 | 2009-03-23 | Novartis Vaccines & Diagnostic | Modificerede saccharider med forbedret stabilitet i vand |
| CA3042073C (en) * | 2003-01-30 | 2022-09-13 | Novartis Vaccines And Diagnostics S.R.L. | Injectable vaccines against multiple meningococcal serogroups |
| SI1670506T1 (sl) | 2003-10-02 | 2013-03-29 | Novartis Ag | Tekoča cepiva proti multiplim meningokoknim seroskupinam |
| GB0405787D0 (en) * | 2004-03-15 | 2004-04-21 | Chiron Srl | Low dose vaccines |
| GB0409745D0 (en) * | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
| GB0500787D0 (en) * | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
| GB0505518D0 (en) * | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
| CN1709505B (zh) * | 2005-07-13 | 2010-06-16 | 北京绿竹生物制药有限公司 | 多价细菌荚膜多糖-蛋白质结合物联合疫苗 |
| CA2621023C (en) * | 2005-09-01 | 2019-07-02 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | Multiple vaccination including serogroup c meningococcus |
| GB0524066D0 (en) * | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| DK2200642T3 (da) * | 2007-10-19 | 2012-07-16 | Novartis Ag | Meningococvaccinepræparater |
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| CN101678094B (zh) | 2014-08-27 |
| JP2010529103A (ja) | 2010-08-26 |
| RU2009149359A (ru) | 2011-07-20 |
| AU2008259423A1 (en) | 2008-12-11 |
| BRPI0811979A2 (pt) | 2014-10-21 |
| WO2008149238A3 (en) | 2009-08-06 |
| AU2014204425B2 (en) | 2015-10-29 |
| CN101678094A (zh) | 2010-03-24 |
| EP2152302A2 (en) | 2010-02-17 |
| ES2555786T3 (es) | 2016-01-08 |
| AU2014204425A1 (en) | 2014-08-07 |
| WO2008149238A2 (en) | 2008-12-11 |
| EP2152302B1 (en) | 2015-10-07 |
| CA2688268A1 (en) | 2008-12-11 |
| US20100203137A1 (en) | 2010-08-12 |
| NZ581367A (en) | 2012-05-25 |
| IN2009KN04098A (enExample) | 2015-08-28 |
| MX2009013112A (es) | 2010-03-01 |
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