RU2009149359A - Состав вакцин против менингита - Google Patents
Состав вакцин против менингита Download PDFInfo
- Publication number
- RU2009149359A RU2009149359A RU2009149359/15A RU2009149359A RU2009149359A RU 2009149359 A RU2009149359 A RU 2009149359A RU 2009149359/15 A RU2009149359/15 A RU 2009149359/15A RU 2009149359 A RU2009149359 A RU 2009149359A RU 2009149359 A RU2009149359 A RU 2009149359A
- Authority
- RU
- Russia
- Prior art keywords
- conjugate
- water
- saccharide
- influenzae
- vaccine
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title claims abstract 25
- 201000009906 Meningitis Diseases 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 claims abstract 45
- 241000606768 Haemophilus influenzae Species 0.000 claims abstract 28
- 241000588650 Neisseria meningitidis Species 0.000 claims abstract 28
- 229960000814 tetanus toxoid Drugs 0.000 claims abstract 15
- 239000002671 adjuvant Substances 0.000 claims abstract 14
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims abstract 9
- 102000014914 Carrier Proteins Human genes 0.000 claims abstract 9
- 108010078791 Carrier Proteins Proteins 0.000 claims abstract 9
- 229940045808 haemophilus influenzae type b Drugs 0.000 claims abstract 8
- 239000012528 membrane Substances 0.000 claims abstract 6
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 claims abstract 4
- 229940001442 combination vaccine Drugs 0.000 claims abstract 4
- 239000007762 w/o emulsion Substances 0.000 claims abstract 4
- 238000004519 manufacturing process Methods 0.000 claims abstract 3
- 239000002775 capsule Substances 0.000 claims abstract 2
- 239000000427 antigen Substances 0.000 claims 18
- 102000036639 antigens Human genes 0.000 claims 18
- 108091007433 antigens Proteins 0.000 claims 18
- 238000000034 method Methods 0.000 claims 17
- 229960003983 diphtheria toxoid Drugs 0.000 claims 9
- 230000000844 anti-bacterial effect Effects 0.000 claims 7
- 241000991587 Enterovirus C Species 0.000 claims 6
- 241000700721 Hepatitis B virus Species 0.000 claims 6
- 201000005702 Pertussis Diseases 0.000 claims 6
- 230000005875 antibody response Effects 0.000 claims 5
- 239000003381 stabilizer Substances 0.000 claims 3
- 230000004044 response Effects 0.000 claims 2
- 239000002569 water oil cream Substances 0.000 claims 2
- 239000000872 buffer Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93323507P | 2007-06-04 | 2007-06-04 | |
| US60/933,235 | 2007-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2009149359A true RU2009149359A (ru) | 2011-07-20 |
Family
ID=40094241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009149359/15A RU2009149359A (ru) | 2007-06-04 | 2008-06-04 | Состав вакцин против менингита |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100203137A1 (enExample) |
| EP (1) | EP2152302B1 (enExample) |
| JP (1) | JP5637848B2 (enExample) |
| CN (1) | CN101678094B (enExample) |
| AU (2) | AU2008259423A1 (enExample) |
| BR (1) | BRPI0811979A2 (enExample) |
| CA (1) | CA2688268A1 (enExample) |
| ES (1) | ES2555786T3 (enExample) |
| IN (1) | IN2009KN04098A (enExample) |
| MX (1) | MX2009013112A (enExample) |
| NZ (1) | NZ581367A (enExample) |
| RU (1) | RU2009149359A (enExample) |
| WO (1) | WO2008149238A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX343752B (es) | 1998-05-01 | 2016-11-22 | Novartis Vaccines & Diagnostics Inc | Antigenos de neisseria meningitidis y composiciones que los contienen. |
| EP1179072A2 (en) | 1999-05-19 | 2002-02-13 | Chiron S.P.A. | Combination neisserial compositions |
| PT2275551E (pt) | 1999-10-29 | 2015-06-29 | Novartis Vaccines & Diagnostic | Péptidos antigénicos de neisseria |
| PT2270030E (pt) | 2000-02-28 | 2012-07-24 | Novartis Vaccines & Diagnostic | Expressão heteróloga de proteínas de neisseria |
| EP1946769B1 (en) * | 2000-06-29 | 2012-05-30 | SmithKline Beecham Biologicals S.A. | Multivalent vaccine composition with reduced dose of Haemophilus influenzae type B |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| HUE045482T2 (hu) | 2005-06-27 | 2019-12-30 | Glaxosmithkline Biologicals Sa | Immunogén készítmény |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| HRP20120433T1 (en) * | 2007-10-19 | 2012-07-31 | Novartis@Ag | Meningococcal vaccine formulations |
| AU2009215364B2 (en) | 2008-02-21 | 2014-09-18 | Glaxosmithkline Biologicals S.A. | Meningococcal fHBP polypeptides |
| JP2011524375A (ja) * | 2008-06-16 | 2011-09-01 | アカデミア シニカ | ＧｌｏｂｏＨおよびＳＳＥＡ３に特異的な免疫反応を誘起する組成物および癌治療におけるその使用 |
| GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| EP3017826A1 (en) * | 2009-03-24 | 2016-05-11 | Novartis AG | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
| CN104548082A (zh) | 2009-03-24 | 2015-04-29 | 诺华股份有限公司 | 为脑膜炎球菌因子h结合蛋白添加佐剂 |
| WO2011161653A1 (en) | 2010-06-25 | 2011-12-29 | Novartis Ag | Combinations of meningococcal factor h binding proteins |
| CA2808975C (en) | 2010-08-23 | 2018-10-30 | Wyeth Llc | Stable formulations of neisseria meningitidis rlp2086 antigens |
| KR101584871B1 (ko) | 2010-09-10 | 2016-01-22 | 와이어쓰 엘엘씨 | 네이세리아 메닝기티디스 orf2086 항원의 비-지질화된 변이체 |
| US20130273098A1 (en) * | 2010-12-10 | 2013-10-17 | Jeffrey T. Blue | Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions |
| IN2012MU00206A (enExample) * | 2012-01-20 | 2013-08-09 | ||
| CA2866406A1 (en) * | 2012-03-08 | 2013-09-12 | Novartis Ag | Adjuvanted formulations of booster vaccines |
| CA2865745C (en) | 2012-03-09 | 2018-01-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| ES2847923T3 (es) | 2012-06-14 | 2021-08-04 | Glaxosmithkline Biologicals Sa | Vacunas contra el meningococo del serogrupo X |
| CA2903716C (en) | 2013-03-08 | 2019-04-09 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| KR20190049940A (ko) | 2015-02-19 | 2019-05-09 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
| CN109890413B (zh) | 2016-09-02 | 2024-04-16 | 赛诺菲巴斯德股份有限公司 | 脑膜炎奈瑟氏菌疫苗 |
| SG11201906519RA (en) | 2017-01-31 | 2019-08-27 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| CA3155669A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| US5425946A (en) | 1992-08-31 | 1995-06-20 | North American Vaccine, Inc. | Vaccines against group C Neisseria meningitidis |
| CA2142981C (en) | 1992-08-31 | 2007-10-23 | Joseph Y. Tai | Vaccines against group c neisseria meningitidis |
| GB9422096D0 (en) * | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
| EP0833662B2 (en) | 1995-06-23 | 2011-01-26 | SmithKline Beecham Biologicals S.A. | A vaccine composition comprsing a Haemophilus influenzae B polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| EP1946769B1 (en) | 2000-06-29 | 2012-05-30 | SmithKline Beecham Biologicals S.A. | Multivalent vaccine composition with reduced dose of Haemophilus influenzae type B |
| CA2435681C (en) | 2001-01-23 | 2011-06-21 | Aventis Pasteur | Multivalent meningococcal polysaccharide-protein conjugate vaccine |
| GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| ES2616180T3 (es) | 2002-03-26 | 2017-06-09 | Glaxosmithkline Biologicals Sa | Sacáridos modificados con estabilidad mejorada en agua para su uso como medicamento |
| DK1587537T3 (da) * | 2003-01-30 | 2012-07-16 | Novartis Ag | Injicerbare vacciner mod multiple meningococ-serogrupper |
| ES2397923T3 (es) | 2003-10-02 | 2013-03-12 | Novartis Ag | Vacunas líquidas para múltiples serogrupos meningocócicos |
| GB0405787D0 (en) * | 2004-03-15 | 2004-04-21 | Chiron Srl | Low dose vaccines |
| GB0409745D0 (en) * | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
| GB0500787D0 (en) * | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
| GB0505518D0 (en) * | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
| CN1709505B (zh) * | 2005-07-13 | 2010-06-16 | 北京绿竹生物制药有限公司 | 多价细菌荚膜多糖-蛋白质结合物联合疫苗 |
| CN102973929B (zh) * | 2005-09-01 | 2017-04-26 | 诺华疫苗和诊断有限两合公司 | 含血清群c脑膜炎球菌的多价疫苗 |
| GB0524066D0 (en) * | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| HRP20120433T1 (en) * | 2007-10-19 | 2012-07-31 | Novartis@Ag | Meningococcal vaccine formulations |
-
2008
- 2008-06-04 IN IN4098KON2009 patent/IN2009KN04098A/en unknown
- 2008-06-04 MX MX2009013112A patent/MX2009013112A/es active IP Right Grant
- 2008-06-04 BR BRPI0811979-1A2A patent/BRPI0811979A2/pt not_active IP Right Cessation
- 2008-06-04 CA CA2688268A patent/CA2688268A1/en not_active Abandoned
- 2008-06-04 RU RU2009149359/15A patent/RU2009149359A/ru not_active Application Discontinuation
- 2008-06-04 WO PCT/IB2008/002121 patent/WO2008149238A2/en not_active Ceased
- 2008-06-04 NZ NZ581367A patent/NZ581367A/en not_active IP Right Cessation
- 2008-06-04 AU AU2008259423A patent/AU2008259423A1/en not_active Abandoned
- 2008-06-04 JP JP2010510910A patent/JP5637848B2/ja not_active Expired - Fee Related
- 2008-06-04 CN CN200880018507.2A patent/CN101678094B/zh not_active Expired - Fee Related
- 2008-06-04 EP EP08789070.3A patent/EP2152302B1/en not_active Not-in-force
- 2008-06-04 US US12/451,831 patent/US20100203137A1/en not_active Abandoned
- 2008-06-04 ES ES08789070.3T patent/ES2555786T3/es active Active
-
2014
- 2014-07-15 AU AU2014204425A patent/AU2014204425B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2555786T3 (es) | 2016-01-08 |
| CA2688268A1 (en) | 2008-12-11 |
| WO2008149238A2 (en) | 2008-12-11 |
| AU2014204425A1 (en) | 2014-08-07 |
| MX2009013112A (es) | 2010-03-01 |
| NZ581367A (en) | 2012-05-25 |
| AU2014204425B2 (en) | 2015-10-29 |
| EP2152302B1 (en) | 2015-10-07 |
| WO2008149238A3 (en) | 2009-08-06 |
| JP2010529103A (ja) | 2010-08-26 |
| CN101678094B (zh) | 2014-08-27 |
| JP5637848B2 (ja) | 2014-12-10 |
| US20100203137A1 (en) | 2010-08-12 |
| EP2152302A2 (en) | 2010-02-17 |
| BRPI0811979A2 (pt) | 2014-10-21 |
| AU2008259423A1 (en) | 2008-12-11 |
| CN101678094A (zh) | 2010-03-24 |
| IN2009KN04098A (enExample) | 2015-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20130826 |