JP5616572B2 - 哺乳類修飾ａｄａｍ１０プロテアーゼまたはそのフラグメント、単離核酸、遺伝子構築物、宿主細胞、抗体、及び産生方法 - Google Patents
哺乳類修飾ａｄａｍ１０プロテアーゼまたはそのフラグメント、単離核酸、遺伝子構築物、宿主細胞、抗体、及び産生方法 Download PDFInfo
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- A61P37/00—Drugs for immunological or allergic disorders
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
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| US63742504P | 2004-12-17 | 2004-12-17 | |
| US60/637,425 | 2004-12-17 | ||
| PCT/AU2005/001917 WO2006063415A1 (en) | 2004-12-17 | 2005-12-19 | Regulation of metalloprotease cleavage of cell surface proteins |
Publications (3)
| Publication Number | Publication Date |
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| JP2008523787A JP2008523787A (ja) | 2008-07-10 |
| JP2008523787A5 JP2008523787A5 (enExample) | 2009-01-29 |
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| JP2007545789A Expired - Fee Related JP5616572B2 (ja) | 2004-12-17 | 2005-12-19 | 哺乳類修飾ａｄａｍ１０プロテアーゼまたはそのフラグメント、単離核酸、遺伝子構築物、宿主細胞、抗体、及び産生方法 |
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| EP (1) | EP1833964B1 (enExample) |
| JP (1) | JP5616572B2 (enExample) |
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| CA (1) | CA2591659A1 (enExample) |
| NZ (1) | NZ556143A (enExample) |
| WO (1) | WO2006063415A1 (enExample) |
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| CA2477932A1 (en) * | 2002-03-08 | 2003-09-18 | Axel Ullrich | Use of egfr transactivation inhibitors in human cancer |
| RU2392961C2 (ru) * | 2004-11-10 | 2010-06-27 | Хубрехт Лабораториум | Лечение аденомы и/или аденокарциномы кишечника с помощью ингибирования активации пути notch |
| JP2008536479A (ja) | 2005-02-11 | 2008-09-11 | ユニバーシティ オブ サザン カリフォルニア | ジスルフィド架橋を有するタンパク質の発現法 |
| EP2514767A1 (en) * | 2006-12-19 | 2012-10-24 | Ablynx N.V. | Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders |
| US8802394B2 (en) | 2008-11-13 | 2014-08-12 | Radu O. Minea | Method of expressing proteins with disulfide bridges with enhanced yields and activity |
| WO2010093976A1 (en) * | 2009-02-12 | 2010-08-19 | University Of Southern California | Bioadhesive patch for sutureless closure of soft tissue |
| AR098953A1 (es) * | 2013-12-24 | 2016-06-22 | Pf Medicament | Anticuerpo anti-adam17 (proteína desintegrina y metaloproteinasa-17) y su uso para el tratamiento de cáncer |
| EP3102940B1 (en) | 2014-02-04 | 2019-06-26 | Monash University | Anti-metalloprotease antibody for diagnosis and treatment of cancers |
| US11160873B2 (en) | 2014-02-04 | 2021-11-02 | Monash University | Anti-metalloprotease antibody for diagnosis and treatment of cancers |
| US20180057601A1 (en) * | 2014-12-24 | 2018-03-01 | Pierre Fabre Medicament | Novel humanized adam17 antibody |
| EP3690022A1 (en) | 2016-05-18 | 2020-08-05 | Keio University | Cell culture medium for culturing organoid, culture method, and organoid |
| EP3934418A4 (en) | 2019-03-08 | 2023-01-18 | Memorial Sloan Kettering Cancer Center | ADAM17 BINDING MOLECULES AND THEIR USES |
| US20250177333A1 (en) * | 2022-03-08 | 2025-06-05 | Nova Southeastern University | Method for treating rheumatoid arthritis (ra) using an enzyme-and substrate selective exosite inhibitor of a disintegrin and metalloprotease 10 (adam10) |
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| US4849338A (en) | 1982-07-16 | 1989-07-18 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4843000A (en) | 1979-12-26 | 1989-06-27 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| AU649066B2 (en) | 1990-07-25 | 1994-05-12 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
| AU6136694A (en) | 1993-02-12 | 1994-08-29 | Repligen Corporation | Methods for generating broadly neutralizing anti-hiv antibodies and antigens capable of eliciting same |
| US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
| JP3974941B2 (ja) | 1995-11-21 | 2007-09-12 | イェール ユニバーシティ | 単分子セグメントの増幅および検出 |
| US5752019A (en) | 1995-12-22 | 1998-05-12 | International Business Machines Corporation | System and method for confirmationally-flexible molecular identification |
| US5835382A (en) | 1996-04-26 | 1998-11-10 | The Scripps Research Institute | Small molecule mimetics of erythropoietin |
| JP2000517185A (ja) * | 1996-08-29 | 2000-12-26 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 新規なメタロプロテアーゼファミリーｋｕｚ |
| US20040224378A1 (en) * | 2002-06-07 | 2004-11-11 | Athersys, Inc. | Methods for using ADAMTS-12, an integrin and metalloprotease with thrombspondin motifs |
| IL150347A (en) | 2002-06-20 | 2008-07-08 | Eci Telecom Ltd | Method and system for span optical power control |
| AU2003900541A0 (en) * | 2003-02-07 | 2003-02-20 | Ludwig Institute For Cancer Research | Modulation of cell adhesion and tumour cell metastasis |
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- 2005-12-19 EP EP05818563.8A patent/EP1833964B1/en not_active Expired - Lifetime
- 2005-12-19 NZ NZ556143A patent/NZ556143A/en not_active IP Right Cessation
- 2005-12-19 AU AU2005316217A patent/AU2005316217A1/en not_active Abandoned
- 2005-12-19 JP JP2007545789A patent/JP5616572B2/ja not_active Expired - Fee Related
- 2005-12-19 WO PCT/AU2005/001917 patent/WO2006063415A1/en not_active Ceased
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| US7960513B2 (en) | 2011-06-14 |
| US20080317763A1 (en) | 2008-12-25 |
| JP2008523787A (ja) | 2008-07-10 |
| NZ556143A (en) | 2010-05-28 |
| CA2591659A1 (en) | 2006-06-22 |
| EP1833964A1 (en) | 2007-09-19 |
| EP1833964A4 (en) | 2009-05-13 |
| EP1833964B1 (en) | 2013-05-22 |
| WO2006063415A1 (en) | 2006-06-22 |
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