CA2591659A1 - Regulation of metalloprotease cleavage of cell surface proteins - Google Patents
Regulation of metalloprotease cleavage of cell surface proteins Download PDFInfo
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- CA2591659A1 CA2591659A1 CA002591659A CA2591659A CA2591659A1 CA 2591659 A1 CA2591659 A1 CA 2591659A1 CA 002591659 A CA002591659 A CA 002591659A CA 2591659 A CA2591659 A CA 2591659A CA 2591659 A1 CA2591659 A1 CA 2591659A1
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Immunology (AREA)
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- Molecular Biology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Rheumatology (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63742504P | 2004-12-17 | 2004-12-17 | |
| US60/637,425 | 2004-12-17 | ||
| PCT/AU2005/001917 WO2006063415A1 (en) | 2004-12-17 | 2005-12-19 | Regulation of metalloprotease cleavage of cell surface proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2591659A1 true CA2591659A1 (en) | 2006-06-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002591659A Abandoned CA2591659A1 (en) | 2004-12-17 | 2005-12-19 | Regulation of metalloprotease cleavage of cell surface proteins |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7960513B2 (enExample) |
| EP (1) | EP1833964B1 (enExample) |
| JP (1) | JP5616572B2 (enExample) |
| AU (1) | AU2005316217A1 (enExample) |
| CA (1) | CA2591659A1 (enExample) |
| NZ (1) | NZ556143A (enExample) |
| WO (1) | WO2006063415A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2477932A1 (en) * | 2002-03-08 | 2003-09-18 | Axel Ullrich | Use of egfr transactivation inhibitors in human cancer |
| RU2392961C2 (ru) * | 2004-11-10 | 2010-06-27 | Хубрехт Лабораториум | Лечение аденомы и/или аденокарциномы кишечника с помощью ингибирования активации пути notch |
| JP2008536479A (ja) | 2005-02-11 | 2008-09-11 | ユニバーシティ オブ サザン カリフォルニア | ジスルフィド架橋を有するタンパク質の発現法 |
| EP2514767A1 (en) * | 2006-12-19 | 2012-10-24 | Ablynx N.V. | Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders |
| US8802394B2 (en) | 2008-11-13 | 2014-08-12 | Radu O. Minea | Method of expressing proteins with disulfide bridges with enhanced yields and activity |
| WO2010093976A1 (en) * | 2009-02-12 | 2010-08-19 | University Of Southern California | Bioadhesive patch for sutureless closure of soft tissue |
| AR098953A1 (es) * | 2013-12-24 | 2016-06-22 | Pf Medicament | Anticuerpo anti-adam17 (proteína desintegrina y metaloproteinasa-17) y su uso para el tratamiento de cáncer |
| EP3102940B1 (en) | 2014-02-04 | 2019-06-26 | Monash University | Anti-metalloprotease antibody for diagnosis and treatment of cancers |
| US11160873B2 (en) | 2014-02-04 | 2021-11-02 | Monash University | Anti-metalloprotease antibody for diagnosis and treatment of cancers |
| US20180057601A1 (en) * | 2014-12-24 | 2018-03-01 | Pierre Fabre Medicament | Novel humanized adam17 antibody |
| EP3690022A1 (en) | 2016-05-18 | 2020-08-05 | Keio University | Cell culture medium for culturing organoid, culture method, and organoid |
| EP3934418A4 (en) | 2019-03-08 | 2023-01-18 | Memorial Sloan Kettering Cancer Center | ADAM17 BINDING MOLECULES AND THEIR USES |
| US20250177333A1 (en) * | 2022-03-08 | 2025-06-05 | Nova Southeastern University | Method for treating rheumatoid arthritis (ra) using an enzyme-and substrate selective exosite inhibitor of a disintegrin and metalloprotease 10 (adam10) |
Family Cites Families (15)
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|---|---|---|---|---|
| US4849338A (en) | 1982-07-16 | 1989-07-18 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4843000A (en) | 1979-12-26 | 1989-06-27 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| AU649066B2 (en) | 1990-07-25 | 1994-05-12 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
| AU6136694A (en) | 1993-02-12 | 1994-08-29 | Repligen Corporation | Methods for generating broadly neutralizing anti-hiv antibodies and antigens capable of eliciting same |
| US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
| JP3974941B2 (ja) | 1995-11-21 | 2007-09-12 | イェール ユニバーシティ | 単分子セグメントの増幅および検出 |
| US5752019A (en) | 1995-12-22 | 1998-05-12 | International Business Machines Corporation | System and method for confirmationally-flexible molecular identification |
| US5835382A (en) | 1996-04-26 | 1998-11-10 | The Scripps Research Institute | Small molecule mimetics of erythropoietin |
| JP2000517185A (ja) * | 1996-08-29 | 2000-12-26 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 新規なメタロプロテアーゼファミリーｋｕｚ |
| US20040224378A1 (en) * | 2002-06-07 | 2004-11-11 | Athersys, Inc. | Methods for using ADAMTS-12, an integrin and metalloprotease with thrombspondin motifs |
| IL150347A (en) | 2002-06-20 | 2008-07-08 | Eci Telecom Ltd | Method and system for span optical power control |
| AU2003900541A0 (en) * | 2003-02-07 | 2003-02-20 | Ludwig Institute For Cancer Research | Modulation of cell adhesion and tumour cell metastasis |
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2005
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- 2005-12-19 EP EP05818563.8A patent/EP1833964B1/en not_active Expired - Lifetime
- 2005-12-19 NZ NZ556143A patent/NZ556143A/en not_active IP Right Cessation
- 2005-12-19 AU AU2005316217A patent/AU2005316217A1/en not_active Abandoned
- 2005-12-19 JP JP2007545789A patent/JP5616572B2/ja not_active Expired - Fee Related
- 2005-12-19 WO PCT/AU2005/001917 patent/WO2006063415A1/en not_active Ceased
- 2005-12-19 CA CA002591659A patent/CA2591659A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005316217A1 (en) | 2006-06-22 |
| US7960513B2 (en) | 2011-06-14 |
| US20080317763A1 (en) | 2008-12-25 |
| JP2008523787A (ja) | 2008-07-10 |
| NZ556143A (en) | 2010-05-28 |
| EP1833964A1 (en) | 2007-09-19 |
| JP5616572B2 (ja) | 2014-10-29 |
| EP1833964A4 (en) | 2009-05-13 |
| EP1833964B1 (en) | 2013-05-22 |
| WO2006063415A1 (en) | 2006-06-22 |
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