JP5614853B2 - チオアミド化合物、その製造方法及び使用方法 - Google Patents

チオアミド化合物、その製造方法及び使用方法 Download PDF

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Publication number
JP5614853B2
JP5614853B2 JP2011533272A JP2011533272A JP5614853B2 JP 5614853 B2 JP5614853 B2 JP 5614853B2 JP 2011533272 A JP2011533272 A JP 2011533272A JP 2011533272 A JP2011533272 A JP 2011533272A JP 5614853 B2 JP5614853 B2 JP 5614853B2
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Prior art keywords
halo
alkyl
alkoxy
alkylthio
methyl
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JP2011533272A
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English (en)
Japanese (ja)
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JP2012506441A5 (OSRAM
JP2012506441A (ja
Inventor
イル ド ファロワ ロイック パトリック ル
イル ド ファロワ ロイック パトリック ル
ヒョウン イク リー
ヒョウン イク リー
フィリップ リード ティモンズ
フィリップ リード ティモンズ
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Merial Ltd
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Merial Ltd
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Publication of JP2012506441A5 publication Critical patent/JP2012506441A5/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP2011533272A 2008-10-21 2009-10-20 チオアミド化合物、その製造方法及び使用方法 Active JP5614853B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10711408P 2008-10-21 2008-10-21
US61/107,114 2008-10-21
PCT/US2009/061337 WO2010048191A1 (en) 2008-10-21 2009-10-20 Thioamide compounds, method of making and method of using thereof

Publications (3)

Publication Number Publication Date
JP2012506441A JP2012506441A (ja) 2012-03-15
JP2012506441A5 JP2012506441A5 (OSRAM) 2012-12-06
JP5614853B2 true JP5614853B2 (ja) 2014-10-29

Family

ID=41404569

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011533272A Active JP5614853B2 (ja) 2008-10-21 2009-10-20 チオアミド化合物、その製造方法及び使用方法

Country Status (15)

Country Link
US (2) US7964621B2 (OSRAM)
EP (1) EP2358687B9 (OSRAM)
JP (1) JP5614853B2 (OSRAM)
KR (2) KR101782308B1 (OSRAM)
CN (1) CN102239151B (OSRAM)
AU (1) AU2009307736B2 (OSRAM)
BR (1) BRPI0920145B8 (OSRAM)
CA (1) CA2741186C (OSRAM)
CL (1) CL2011000917A1 (OSRAM)
EA (1) EA026649B1 (OSRAM)
ES (1) ES2393965T3 (OSRAM)
MX (1) MX2011004217A (OSRAM)
NZ (1) NZ592382A (OSRAM)
WO (1) WO2010048191A1 (OSRAM)
ZA (1) ZA201103033B (OSRAM)

Cited By (2)

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JPH086603B2 (ja) 1986-02-27 1996-01-29 ベ−・ベ−・ツエ−・アクチエンゲゼルシヤフト・ブラウン・ボヴエリ・ウント・コンパニイ 舶用過給式デイ−ゼル機関
CN103003144B (zh) * 2010-08-10 2016-05-18 川崎重工业株式会社 原动机系统及船舶

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PH12018501647A1 (en) 2011-09-12 2019-02-27 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
SG11201404595TA (en) 2012-02-06 2014-09-26 Merial Ltd Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
CN103073487B (zh) * 2013-01-15 2014-11-19 西华大学 N-双取代硫代乙酰胺类化合物的合成方法
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
SG11201603430XA (en) 2013-11-01 2016-05-30 Merial Ltd Antiparasitic and pesticidal isoxazoline compounds
CN104610110A (zh) * 2014-03-12 2015-05-13 广东东阳光药业有限公司 一种制备4-取代硫代苯甲酰胺衍生物的方法
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
US10045979B2 (en) 2014-05-19 2018-08-14 Merial Inc. Anthelmintic compounds
ES2887302T3 (es) 2014-10-31 2021-12-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
US10081656B2 (en) 2015-05-20 2018-09-25 Merial, Inc. Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3525590B1 (en) 2016-10-14 2025-08-20 Boehringer Ingelheim Vetmedica GmbH Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
CN111194316A (zh) 2017-08-14 2020-05-22 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的吡唑-异噁唑啉化合物
IL279977B2 (en) 2018-07-09 2024-06-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
KR102281492B1 (ko) * 2018-12-24 2021-07-26 동인당제약 주식회사 세벨라머 함유 경구투여용 현탁제 조성물 및 그 제조방법
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
CN111781291A (zh) * 2020-06-23 2020-10-16 广西壮族自治区水产科学研究院 一种水中13种大环内酯类抗生素的高分辨质谱检测方法
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer
CN117837424A (zh) * 2024-02-04 2024-04-09 黄淮学院 一种控制农作物灰飞虱的方法

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US6239077B1 (en) 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
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AR035531A1 (es) * 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
EP1390344B1 (en) 2001-05-15 2006-12-27 Novartis AG Benzamidoacetonitrile derivatives and their use as antiparasitics
TWI236341B (en) 2001-06-15 2005-07-21 Novartis Ag Aminoacetonitrile compounds for use in the control of endoparasites
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH086603B2 (ja) 1986-02-27 1996-01-29 ベ−・ベ−・ツエ−・アクチエンゲゼルシヤフト・ブラウン・ボヴエリ・ウント・コンパニイ 舶用過給式デイ−ゼル機関
CN103003144B (zh) * 2010-08-10 2016-05-18 川崎重工业株式会社 原动机系统及船舶

Also Published As

Publication number Publication date
US20100130565A1 (en) 2010-05-27
ES2393965T9 (es) 2013-07-19
EP2358687B1 (en) 2012-09-19
BRPI0920145B1 (pt) 2021-03-30
US8314146B2 (en) 2012-11-20
BRPI0920145B8 (pt) 2021-05-25
KR20170003704A (ko) 2017-01-09
CA2741186C (en) 2016-07-19
CA2741186A1 (en) 2010-04-29
ES2393965T3 (es) 2013-01-03
NZ592382A (en) 2013-03-28
EA026649B1 (ru) 2017-05-31
CL2011000917A1 (es) 2011-09-16
EP2358687A1 (en) 2011-08-24
AU2009307736A1 (en) 2010-04-29
KR101782311B1 (ko) 2017-09-27
ZA201103033B (en) 2012-02-29
CN102239151A (zh) 2011-11-09
EP2358687B9 (en) 2013-04-17
KR20110071140A (ko) 2011-06-28
AU2009307736B2 (en) 2015-02-05
US20110190231A1 (en) 2011-08-04
US7964621B2 (en) 2011-06-21
BRPI0920145A2 (pt) 2017-06-06
EA201100666A1 (ru) 2011-12-30
JP2012506441A (ja) 2012-03-15
WO2010048191A1 (en) 2010-04-29
MX2011004217A (es) 2011-06-20
KR101782308B1 (ko) 2017-09-27
CN102239151B (zh) 2014-07-02

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