JP5600432B2 - コアセルベート化誘導リポソーム被包法及びその調合物 - Google Patents

コアセルベート化誘導リポソーム被包法及びその調合物 Download PDF

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JP5600432B2
JP5600432B2 JP2009504301A JP2009504301A JP5600432B2 JP 5600432 B2 JP5600432 B2 JP 5600432B2 JP 2009504301 A JP2009504301 A JP 2009504301A JP 2009504301 A JP2009504301 A JP 2009504301A JP 5600432 B2 JP5600432 B2 JP 5600432B2
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lipid
solution
aqueous
added
amikacin
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JP2009532481A (ja
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ウラジミール マリニン，
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インスメッド， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2009504301A 2006-04-06 2007-04-04 コアセルベート化誘導リポソーム被包法及びその調合物 Active JP5600432B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78968806P 2006-04-06 2006-04-06
US60/789,688 2006-04-06
PCT/US2007/008500 WO2007117550A2 (en) 2006-04-06 2007-04-04 Methods for coacervation induced liposomal encapsulation and formulations thereof

Related Child Applications (1)

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JP2014093375A Division JP2014139248A (ja) 2006-04-06 2014-04-30 コアセルベート化誘導リポソーム被包法及びその調合物

Publications (2)

Publication Number Publication Date
JP2009532481A JP2009532481A (ja) 2009-09-10
JP5600432B2 true JP5600432B2 (ja) 2014-10-01

Family

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Family Applications (5)

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JP2009504301A Active JP5600432B2 (ja) 2006-04-06 2007-04-04 コアセルベート化誘導リポソーム被包法及びその調合物
JP2014093375A Pending JP2014139248A (ja) 2006-04-06 2014-04-30 コアセルベート化誘導リポソーム被包法及びその調合物
JP2014165736A Active JP6088469B2 (ja) 2006-04-06 2014-08-18 コアセルベート化誘導リポソーム被包法及びその調合物
JP2016203842A Pending JP2017008114A (ja) 2006-04-06 2016-10-17 コアセルベート化誘導リポソーム被包法及びその調合物
JP2018000447A Pending JP2018048212A (ja) 2006-04-06 2018-01-05 コアセルベート化誘導リポソーム被包法及びその調合物

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JP2014093375A Pending JP2014139248A (ja) 2006-04-06 2014-04-30 コアセルベート化誘導リポソーム被包法及びその調合物
JP2014165736A Active JP6088469B2 (ja) 2006-04-06 2014-08-18 コアセルベート化誘導リポソーム被包法及びその調合物
JP2016203842A Pending JP2017008114A (ja) 2006-04-06 2016-10-17 コアセルベート化誘導リポソーム被包法及びその調合物
JP2018000447A Pending JP2018048212A (ja) 2006-04-06 2018-01-05 コアセルベート化誘導リポソーム被包法及びその調合物

Country Status (5)

Country Link
US (1) US20080089927A1 (enExample)
EP (2) EP2012750B1 (enExample)
JP (5) JP5600432B2 (enExample)
ES (1) ES2668554T3 (enExample)
WO (1) WO2007117550A2 (enExample)

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CN116437929B (zh) * 2020-07-02 2025-11-11 普渡研究基金会 抗微生物化合物的吸入制剂
CN116035946B (zh) * 2022-10-25 2025-07-25 上海美自无双生物科技有限公司 一种通过复合凝聚法制备神经酰胺细胞磷脂组合物的方法及应用
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Also Published As

Publication number Publication date
ES2668554T3 (es) 2018-05-18
JP2009532481A (ja) 2009-09-10
EP3354260B1 (en) 2020-12-09
EP2012750B1 (en) 2018-02-21
WO2007117550A2 (en) 2007-10-18
JP2014210819A (ja) 2014-11-13
EP2012750A2 (en) 2009-01-14
WO2007117550A3 (en) 2008-11-27
JP2014139248A (ja) 2014-07-31
JP6088469B2 (ja) 2017-03-01
JP2017008114A (ja) 2017-01-12
EP2012750A4 (en) 2013-02-20
US20080089927A1 (en) 2008-04-17
EP3354260A1 (en) 2018-08-01
JP2018048212A (ja) 2018-03-29

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