JP5581490B2 - 抗体媒介による細菌のクオラムセンシングの破壊 - Google Patents
抗体媒介による細菌のクオラムセンシングの破壊 Download PDFInfo
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Classifications
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| EP2911694A4 (en) | 2012-10-26 | 2016-07-13 | Sorrento Therapeutics Inc | ANTI-INFECTIOUS BINDING PROTEINS THAT BIND TO AIP2 |
| DE102013211850A1 (de) * | 2013-06-21 | 2014-12-24 | Gilupi Gmbh | Schnelltest zum Nachweisen von Erregermaterial, insbesondere zur Unterstützung der Diagnose einer Sepsis, sowie Kit und Vorrichtung zur Durchführung eines Sepsistests |
| NZ717476A (en) * | 2013-08-01 | 2022-04-29 | Univ Catholique Louvain | Anti-garp protein and uses thereof |
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| EP0932613B1 (en) * | 1996-05-22 | 2005-03-09 | New York University | Blocking expression of virulence factors in s. aureus |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| WO2001085664A2 (en) * | 2000-05-10 | 2001-11-15 | Princeton University | Compounds and methods for regulating bacterial growth and pathogenesis |
| US7786257B2 (en) | 2000-12-18 | 2010-08-31 | University Of Kansas | Signal-1/signal-2 bifunctional peptide inhibitors |
| US6463632B2 (en) * | 2001-02-07 | 2002-10-15 | Hans Oetiker Ag Maschinen-Und Apparatefabrik | Guide arrangement for tightening tool emplacement in hose clamps provided with plastically deformable ears |
| CN1164612C (zh) * | 2001-09-11 | 2004-09-01 | 四川新泰克控股有限责任公司 | 人工组合的抗菌工程多肽及其制备方法 |
| CA2495725C (en) | 2002-08-13 | 2013-06-25 | Haptogen Ltd | Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody |
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| CN101835484B (zh) | 2014-07-16 |
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| JP2014221774A (ja) | 2014-11-27 |
| WO2009055054A3 (en) | 2009-09-03 |
| JP2011500814A (ja) | 2011-01-06 |
| WO2009055054A2 (en) | 2009-04-30 |
| CN101835484A (zh) | 2010-09-15 |
| CA2703133C (en) | 2017-09-19 |
| CN104211775A (zh) | 2014-12-17 |
| US9394371B2 (en) | 2016-07-19 |
| EP2842565A1 (en) | 2015-03-04 |
| CA2975568A1 (en) | 2009-04-30 |
| US20170043020A1 (en) | 2017-02-16 |
| JP2018021021A (ja) | 2018-02-08 |
| CA2703133A1 (en) | 2009-04-30 |
| KR101557173B1 (ko) | 2015-10-05 |
| KR20100102100A (ko) | 2010-09-20 |
| EP2211889B1 (en) | 2014-08-20 |
| JP6183910B2 (ja) | 2017-08-23 |
| ES2603061T3 (es) | 2017-02-23 |
| EP2842565B1 (en) | 2016-08-24 |
| EP2211889A2 (en) | 2010-08-04 |
| US20100291093A1 (en) | 2010-11-18 |
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