JP5577345B2 - 線維芽細胞成長因子受容体３（ｆｇｆｒ−３）阻害剤および治療方法 - Google Patents
線維芽細胞成長因子受容体３（ｆｇｆｒ−３）阻害剤および治療方法 Download PDFInfo
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Landscapes
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| PCT/US2009/060840 WO2010048026A2 (en) | 2008-10-20 | 2009-10-15 | Fibroblast growth factor receptor-3 (fgfr-3) inhibitors and methods of treatment |
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| JP2012505912A JP2012505912A (ja) | 2012-03-08 |
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| TWI381848B (zh) * | 2008-10-20 | 2013-01-11 | Imclone Llc | 抗纖維母細胞生長因子受體-3 (fgfr-3) 抗體及包含其之醫藥組合物 |
| PE20120553A1 (es) | 2009-03-25 | 2012-05-18 | Genentech Inc | Anticuerpos anti-fgfr3 |
| WO2013088191A1 (en) | 2011-12-12 | 2013-06-20 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Antagonist of the fibroblast growth factor receptor 3 (fgfr3) for use in the treatment or the prevention of skeletal disorders linked with abnormal activation of fgfr3 |
| EA201591324A1 (ru) | 2013-01-16 | 2016-01-29 | Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль) | Полипептид растворимого рецептора 3 фактора роста фибробластов (fgr3) для применения с целью предотвращения или лечения нарушений, связанных с замедлением роста скелета |
| MX2015011428A (es) | 2013-03-06 | 2016-02-03 | Genentech Inc | Metodos para tratar y prevenir la resistencia a los farmacos para el cancer. |
| TWI541022B (zh) * | 2013-12-18 | 2016-07-11 | 應克隆公司 | 針對纖維母細胞生長因子受體－３（ｆｇｆｒ３）之化合物及治療方法 |
| WO2015148708A1 (en) | 2014-03-25 | 2015-10-01 | Regeneron Pharmaceuticals, Inc. | Fgf21 receptor agonists and uses thereof |
| WO2015187521A2 (en) * | 2014-06-03 | 2015-12-10 | Merck Sharp & Dohme Corp. | Anti-blys antibodies |
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| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| EP0318554B2 (en) | 1987-05-21 | 2005-01-12 | Micromet AG | Targeted multifunctional proteins |
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| HRP20130163T1 (hr) * | 2006-09-07 | 2013-03-31 | Crucell Holland B.V. | Ljudske molekule za vezanje koje mogu neutralizirati virus influence h5n1 i njihova uporaba |
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| TWI381848B (zh) * | 2008-10-20 | 2013-01-11 | Imclone Llc | 抗纖維母細胞生長因子受體-3 (fgfr-3) 抗體及包含其之醫藥組合物 |
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| EA201170590A1 (ru) | 2011-10-31 |
| BRPI0919832A8 (pt) | 2019-01-08 |
| JP2012505912A (ja) | 2012-03-08 |
| US8404240B2 (en) | 2013-03-26 |
| WO2010048026A3 (en) | 2010-07-15 |
| MX2011004317A (es) | 2011-06-24 |
| CA2741127C (en) | 2015-06-02 |
| AU2009307841A1 (en) | 2010-04-29 |
| CN103524620A (zh) | 2014-01-22 |
| EA021584B1 (ru) | 2015-07-30 |
| EP2342232A2 (en) | 2011-07-13 |
| AR073770A1 (es) | 2010-12-01 |
| US20120009200A1 (en) | 2012-01-12 |
| CN102186884A (zh) | 2011-09-14 |
| US20120219563A1 (en) | 2012-08-30 |
| CN102186884B (zh) | 2014-08-13 |
| US8043618B2 (en) | 2011-10-25 |
| IL211807A0 (en) | 2011-06-30 |
| TW201026325A (en) | 2010-07-16 |
| WO2010048026A2 (en) | 2010-04-29 |
| TWI381848B (zh) | 2013-01-11 |
| UA101681C2 (ru) | 2013-04-25 |
| KR20110056554A (ko) | 2011-05-30 |
| NZ592369A (en) | 2013-02-22 |
| AU2009307841B2 (en) | 2013-09-12 |
| US20100098696A1 (en) | 2010-04-22 |
| ZA201101938B (en) | 2012-08-29 |
| KR101370798B1 (ko) | 2014-03-14 |
| BRPI0919832A2 (pt) | 2015-12-15 |
| CA2741127A1 (en) | 2010-04-29 |
| US8182815B2 (en) | 2012-05-22 |
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