JP5562939B2 - アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法 - Google Patents

アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法 Download PDF

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JP5562939B2
JP5562939B2 JP2011504178A JP2011504178A JP5562939B2 JP 5562939 B2 JP5562939 B2 JP 5562939B2 JP 2011504178 A JP2011504178 A JP 2011504178A JP 2011504178 A JP2011504178 A JP 2011504178A JP 5562939 B2 JP5562939 B2 JP 5562939B2
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cells
compound
oxygen atom
organ
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JP2011516572A5 (https=
JP2011516572A (ja
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マイケル エガン トーマス
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University of North Carolina at Chapel Hill
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011504178A 2008-04-09 2009-04-09 アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法 Expired - Fee Related JP5562939B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4358608P 2008-04-09 2008-04-09
US61/043,586 2008-04-09
PCT/US2009/040098 WO2009126822A2 (en) 2008-04-09 2009-04-09 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation

Publications (3)

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JP2011516572A JP2011516572A (ja) 2011-05-26
JP2011516572A5 JP2011516572A5 (https=) 2012-05-24
JP5562939B2 true JP5562939B2 (ja) 2014-07-30

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JP2011504178A Expired - Fee Related JP5562939B2 (ja) 2008-04-09 2009-04-09 アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法

Country Status (14)

Country Link
US (1) US8809303B2 (https=)
EP (1) EP2268286B1 (https=)
JP (1) JP5562939B2 (https=)
KR (1) KR20100135886A (https=)
CN (1) CN102083443B (https=)
AU (1) AU2009234156A1 (https=)
BR (1) BRPI0911195A2 (https=)
CA (1) CA2721082A1 (https=)
EA (1) EA201001450A1 (https=)
ES (1) ES2569608T3 (https=)
IL (1) IL208565A0 (https=)
MX (1) MX2010011050A (https=)
WO (1) WO2009126822A2 (https=)
ZA (1) ZA201007735B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0911195A2 (pt) 2008-04-09 2017-06-20 The Univ Of North Caroline At Chapel Hill métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular
BRPI1010516A2 (pt) * 2009-04-09 2015-08-25 Univ North Carolina Métodos de tratamento de edema relacionados à isquemia-reperfusão
CN103160570A (zh) * 2011-12-09 2013-06-19 彩虹天健康科技研究(北京)有限责任公司 Unc-51激酶和pp1磷酸酶相互作用机制的发现
ES2985591T3 (es) * 2018-02-12 2024-11-06 Inimmune Corp Ligandos de receptores tipo Toll
CN108836971B (zh) * 2018-08-16 2020-10-30 青岛大学 Ws6对小梁网细胞肌动蛋白形成的影响

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628984A (en) 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US6113918A (en) 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6013640A (en) * 1998-08-21 2000-01-11 Ribi Immunochem Research, Inc. Phosphoglycolipid and methods for its use
WO2001053462A1 (en) * 2000-01-19 2001-07-26 University Of North Carolina At Chapel Hill Liver tissue source
US6699846B2 (en) * 2000-03-17 2004-03-02 Corixa Corporation Mono- and disaccharides for the treatment of nitric oxide related disorders
WO2003105909A1 (ja) 2002-06-13 2003-12-24 三菱ウェルファーマ株式会社 肝虚血再灌流傷害の予防及び／又は治療のための医薬並びに移植肝臓の保護剤
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
WO2005039504A2 (en) 2003-10-24 2005-05-06 Eisai Co., Ltd. Compounds and methods for treating toll-like receptor 2-related diseases and conditions
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
US7928132B2 (en) 2004-08-06 2011-04-19 Ohio University Methods for the amelioration of episodes of acute or chronic ulcerative colitis
WO2005117975A2 (en) 2004-05-28 2005-12-15 Cedars-Sinai Medical Center Methods for treating vascular disease
ITMI20060530A1 (it) 2006-03-22 2007-09-23 Univ Milano Bicocca Antinfiammatori a struttura monosaccaridica
US8734788B2 (en) 2007-08-03 2014-05-27 Opsona Therapeutics Ltd Composition and method for treatment of reperfusion injury and tissue damage
BRPI0911195A2 (pt) 2008-04-09 2017-06-20 The Univ Of North Caroline At Chapel Hill métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular
BRPI1010516A2 (pt) 2009-04-09 2015-08-25 Univ North Carolina Métodos de tratamento de edema relacionados à isquemia-reperfusão

Also Published As

Publication number Publication date
ES2569608T3 (es) 2016-05-11
US20110053871A1 (en) 2011-03-03
IL208565A0 (en) 2010-12-30
EP2268286A1 (en) 2011-01-05
US8809303B2 (en) 2014-08-19
KR20100135886A (ko) 2010-12-27
ZA201007735B (en) 2013-04-24
CA2721082A1 (en) 2009-10-15
EP2268286A4 (en) 2011-10-12
MX2010011050A (es) 2010-11-01
CN102083443A (zh) 2011-06-01
WO2009126822A2 (en) 2009-10-15
CN102083443B (zh) 2014-01-15
EP2268286B1 (en) 2016-04-06
JP2011516572A (ja) 2011-05-26
BRPI0911195A2 (pt) 2017-06-20
AU2009234156A1 (en) 2009-10-15
EA201001450A1 (ru) 2011-08-30
WO2009126822A9 (en) 2009-12-17

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