EA201001450A1 - Способы регулирования реаранжировки актинового цитоскелета и формирования межклеточных промежутков - Google Patents

Способы регулирования реаранжировки актинового цитоскелета и формирования межклеточных промежутков

Info

Publication number
EA201001450A1
EA201001450A1 EA201001450A EA201001450A EA201001450A1 EA 201001450 A1 EA201001450 A1 EA 201001450A1 EA 201001450 A EA201001450 A EA 201001450A EA 201001450 A EA201001450 A EA 201001450A EA 201001450 A1 EA201001450 A1 EA 201001450A1
Authority
EA
Eurasian Patent Office
Prior art keywords
formation
actin cytoskeleton
methods
organization
inter
Prior art date
Application number
EA201001450A
Other languages
English (en)
Russian (ru)
Inventor
Томас Майкл Игэн
Original Assignee
Зе Юнивёсэти Оф Ноф Кэрэлайн Эт Чэпл Хил
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Зе Юнивёсэти Оф Ноф Кэрэлайн Эт Чэпл Хил filed Critical Зе Юнивёсэти Оф Ноф Кэрэлайн Эт Чэпл Хил
Publication of EA201001450A1 publication Critical patent/EA201001450A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201001450A 2008-04-09 2009-04-09 Способы регулирования реаранжировки актинового цитоскелета и формирования межклеточных промежутков EA201001450A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4358608P 2008-04-09 2008-04-09
PCT/US2009/040098 WO2009126822A2 (en) 2008-04-09 2009-04-09 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation

Publications (1)

Publication Number Publication Date
EA201001450A1 true EA201001450A1 (ru) 2011-08-30

Family

ID=41162617

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001450A EA201001450A1 (ru) 2008-04-09 2009-04-09 Способы регулирования реаранжировки актинового цитоскелета и формирования межклеточных промежутков

Country Status (14)

Country Link
US (1) US8809303B2 (https=)
EP (1) EP2268286B1 (https=)
JP (1) JP5562939B2 (https=)
KR (1) KR20100135886A (https=)
CN (1) CN102083443B (https=)
AU (1) AU2009234156A1 (https=)
BR (1) BRPI0911195A2 (https=)
CA (1) CA2721082A1 (https=)
EA (1) EA201001450A1 (https=)
ES (1) ES2569608T3 (https=)
IL (1) IL208565A0 (https=)
MX (1) MX2010011050A (https=)
WO (1) WO2009126822A2 (https=)
ZA (1) ZA201007735B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100135886A (ko) 2008-04-09 2010-12-27 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법
AU2010233151A1 (en) * 2009-04-09 2011-11-17 The University Of North Carolina At Chapel Hill Methods of treating edema related to ischemia-reperfusion
CN103160570A (zh) * 2011-12-09 2013-06-19 彩虹天健康科技研究(北京)有限责任公司 Unc-51激酶和pp1磷酸酶相互作用机制的发现
JP7362667B2 (ja) 2018-02-12 2023-10-17 イニミューン・コーポレーション Ｔｏｌｌ様受容体リガンド
CN108836971B (zh) * 2018-08-16 2020-10-30 青岛大学 Ws6对小梁网细胞肌动蛋白形成的影响

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628984A (en) 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
US5843024A (en) * 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US6113918A (en) 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6013640A (en) * 1998-08-21 2000-01-11 Ribi Immunochem Research, Inc. Phosphoglycolipid and methods for its use
WO2001053462A1 (en) 2000-01-19 2001-07-26 University Of North Carolina At Chapel Hill Liver tissue source
US6699846B2 (en) 2000-03-17 2004-03-02 Corixa Corporation Mono- and disaccharides for the treatment of nitric oxide related disorders
JPWO2003105909A1 (ja) * 2002-06-13 2005-10-13 三菱ウェルファーマ株式会社 肝虚血再灌流傷害の予防及び／又は治療のための医薬並びに移植肝臓の保護剤
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
US7202234B2 (en) 2003-10-24 2007-04-10 Eisai Co., Ltd. Compounds and methods for treating Toll-like receptor 2-related diseases and conditions
US7928132B2 (en) 2004-08-06 2011-04-19 Ohio University Methods for the amelioration of episodes of acute or chronic ulcerative colitis
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
US7959918B2 (en) * 2004-05-28 2011-06-14 Cedars-Sinai Medical Center Methods for treating vascular disease
ITMI20060530A1 (it) * 2006-03-22 2007-09-23 Univ Milano Bicocca Antinfiammatori a struttura monosaccaridica
EP2170366B1 (en) 2007-08-03 2013-11-06 Opsona Therapeutics Limited Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage
KR20100135886A (ko) 2008-04-09 2010-12-27 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법
AU2010233151A1 (en) 2009-04-09 2011-11-17 The University Of North Carolina At Chapel Hill Methods of treating edema related to ischemia-reperfusion

Also Published As

Publication number Publication date
AU2009234156A1 (en) 2009-10-15
ZA201007735B (en) 2013-04-24
EP2268286A1 (en) 2011-01-05
CN102083443A (zh) 2011-06-01
EP2268286B1 (en) 2016-04-06
WO2009126822A2 (en) 2009-10-15
IL208565A0 (en) 2010-12-30
US8809303B2 (en) 2014-08-19
BRPI0911195A2 (pt) 2017-06-20
MX2010011050A (es) 2010-11-01
KR20100135886A (ko) 2010-12-27
CA2721082A1 (en) 2009-10-15
WO2009126822A9 (en) 2009-12-17
ES2569608T3 (es) 2016-05-11
JP5562939B2 (ja) 2014-07-30
JP2011516572A (ja) 2011-05-26
EP2268286A4 (en) 2011-10-12
CN102083443B (zh) 2014-01-15
US20110053871A1 (en) 2011-03-03

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