AU2009234156A1 - Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation - Google Patents

Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation Download PDF

Info

Publication number
AU2009234156A1
AU2009234156A1 AU2009234156A AU2009234156A AU2009234156A1 AU 2009234156 A1 AU2009234156 A1 AU 2009234156A1 AU 2009234156 A AU2009234156 A AU 2009234156A AU 2009234156 A AU2009234156 A AU 2009234156A AU 2009234156 A1 AU2009234156 A1 AU 2009234156A1
Authority
AU
Australia
Prior art keywords
cell
compound
ischemia
cells
actin cytoskeletal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009234156A
Other languages
English (en)
Inventor
Thomas Michael Egan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of North Carolina at Chapel Hill
Original Assignee
University of North Carolina at Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of North Carolina at Chapel Hill filed Critical University of North Carolina at Chapel Hill
Publication of AU2009234156A1 publication Critical patent/AU2009234156A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2009234156A 2008-04-09 2009-04-09 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation Abandoned AU2009234156A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4358608P 2008-04-09 2008-04-09
US61/043,586 2008-04-09
PCT/US2009/040098 WO2009126822A2 (en) 2008-04-09 2009-04-09 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation

Publications (1)

Publication Number Publication Date
AU2009234156A1 true AU2009234156A1 (en) 2009-10-15

Family

ID=41162617

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009234156A Abandoned AU2009234156A1 (en) 2008-04-09 2009-04-09 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation

Country Status (14)

Country Link
US (1) US8809303B2 (https=)
EP (1) EP2268286B1 (https=)
JP (1) JP5562939B2 (https=)
KR (1) KR20100135886A (https=)
CN (1) CN102083443B (https=)
AU (1) AU2009234156A1 (https=)
BR (1) BRPI0911195A2 (https=)
CA (1) CA2721082A1 (https=)
EA (1) EA201001450A1 (https=)
ES (1) ES2569608T3 (https=)
IL (1) IL208565A0 (https=)
MX (1) MX2010011050A (https=)
WO (1) WO2009126822A2 (https=)
ZA (1) ZA201007735B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0911195A2 (pt) 2008-04-09 2017-06-20 The Univ Of North Caroline At Chapel Hill métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular
BRPI1010516A2 (pt) * 2009-04-09 2015-08-25 Univ North Carolina Métodos de tratamento de edema relacionados à isquemia-reperfusão
CN103160570A (zh) * 2011-12-09 2013-06-19 彩虹天健康科技研究(北京)有限责任公司 Unc-51激酶和pp1磷酸酶相互作用机制的发现
ES2985591T3 (es) * 2018-02-12 2024-11-06 Inimmune Corp Ligandos de receptores tipo Toll
CN108836971B (zh) * 2018-08-16 2020-10-30 青岛大学 Ws6对小梁网细胞肌动蛋白形成的影响

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628984A (en) 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US6113918A (en) 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6013640A (en) * 1998-08-21 2000-01-11 Ribi Immunochem Research, Inc. Phosphoglycolipid and methods for its use
WO2001053462A1 (en) * 2000-01-19 2001-07-26 University Of North Carolina At Chapel Hill Liver tissue source
US6699846B2 (en) * 2000-03-17 2004-03-02 Corixa Corporation Mono- and disaccharides for the treatment of nitric oxide related disorders
WO2003105909A1 (ja) 2002-06-13 2003-12-24 三菱ウェルファーマ株式会社 肝虚血再灌流傷害の予防及び／又は治療のための医薬並びに移植肝臓の保護剤
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
WO2005039504A2 (en) 2003-10-24 2005-05-06 Eisai Co., Ltd. Compounds and methods for treating toll-like receptor 2-related diseases and conditions
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
US7928132B2 (en) 2004-08-06 2011-04-19 Ohio University Methods for the amelioration of episodes of acute or chronic ulcerative colitis
WO2005117975A2 (en) 2004-05-28 2005-12-15 Cedars-Sinai Medical Center Methods for treating vascular disease
ITMI20060530A1 (it) 2006-03-22 2007-09-23 Univ Milano Bicocca Antinfiammatori a struttura monosaccaridica
US8734788B2 (en) 2007-08-03 2014-05-27 Opsona Therapeutics Ltd Composition and method for treatment of reperfusion injury and tissue damage
BRPI0911195A2 (pt) 2008-04-09 2017-06-20 The Univ Of North Caroline At Chapel Hill métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular
BRPI1010516A2 (pt) 2009-04-09 2015-08-25 Univ North Carolina Métodos de tratamento de edema relacionados à isquemia-reperfusão

Also Published As

Publication number Publication date
ES2569608T3 (es) 2016-05-11
US20110053871A1 (en) 2011-03-03
IL208565A0 (en) 2010-12-30
EP2268286A1 (en) 2011-01-05
US8809303B2 (en) 2014-08-19
KR20100135886A (ko) 2010-12-27
ZA201007735B (en) 2013-04-24
CA2721082A1 (en) 2009-10-15
EP2268286A4 (en) 2011-10-12
MX2010011050A (es) 2010-11-01
CN102083443A (zh) 2011-06-01
WO2009126822A2 (en) 2009-10-15
CN102083443B (zh) 2014-01-15
EP2268286B1 (en) 2016-04-06
JP2011516572A (ja) 2011-05-26
BRPI0911195A2 (pt) 2017-06-20
EA201001450A1 (ru) 2011-08-30
WO2009126822A9 (en) 2009-12-17
JP5562939B2 (ja) 2014-07-30

Similar Documents

Publication Publication Date Title
JP6879980B2 (ja) ウロリチンまたはその前駆体の投与によるオートファジーの増強または寿命の延長
US20120064044A1 (en) Methods of treating edema related to ischemia-reperfusion
EP2268286B1 (en) Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation
CN111655258B (zh) 用于冷冻保存的组合物和其使用方法
CN109803664A (zh) 用于改善细胞、组织和器官的活力和功能的试剂、组合物和方法
Turbow et al. Direct effects of 6‐aminonicotinamide on the developing rat embryo in vitro and in vivo
SK5796A3 (en) Use of indenoindole compounds
JP2017535546A (ja) 新規な方法
RU2521199C1 (ru) Фармацевтическая композиция для профилактики и лечения сосудистых нарушений и нейропатий
US20060014709A1 (en) Drug or cosmetic
JP6878418B2 (ja) 移植片拒絶反応の処置方法
US10828338B2 (en) Methods for improving cognition and slowing cognitive impairment using nonviable lyophilized pluripotent stem cells
US6313104B1 (en) Organoprotective solutions
JP2022083279A (ja) 腎臓保護用の組成物
EP1142570A1 (en) Angiogenesis inhibitor
Zhang et al. The Immunomodulatory Role of Protein Kinase A Signaling in Liver Ischemia/Reperfusion Injury in Mice.: Abstract# P-157
CN103989701A (zh) 聚乙二醇4000或聚乙二醇6000在制备预防或治疗水母毒素心脏毒性药物中的应用
KR20170110520A (ko) mTOR 억제제 및 N-아세틸시스테인을 포함하는 간섬유화 억제용 조성물

Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period