MX2010011050A - Metodos para regular el reodernamiento citoesqueletico de actina y la formacion de aberturas intercelulares. - Google Patents
Metodos para regular el reodernamiento citoesqueletico de actina y la formacion de aberturas intercelulares.Info
- Publication number
- MX2010011050A MX2010011050A MX2010011050A MX2010011050A MX2010011050A MX 2010011050 A MX2010011050 A MX 2010011050A MX 2010011050 A MX2010011050 A MX 2010011050A MX 2010011050 A MX2010011050 A MX 2010011050A MX 2010011050 A MX2010011050 A MX 2010011050A
- Authority
- MX
- Mexico
- Prior art keywords
- cell
- carbon atoms
- compound
- actin
- cells
- Prior art date
Links
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- 239000000347 magnesium hydroxide Substances 0.000 description 1
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- AXLHVTKGDPVANO-UHFFFAOYSA-N methyl 2-amino-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate Chemical compound COC(=O)C(N)CNC(=O)OC(C)(C)C AXLHVTKGDPVANO-UHFFFAOYSA-N 0.000 description 1
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- 125000005981 pentynyl group Chemical group 0.000 description 1
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- 239000006187 pill Substances 0.000 description 1
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- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- BDAWXSQJJCIFIK-UHFFFAOYSA-N potassium methoxide Chemical compound [K+].[O-]C BDAWXSQJJCIFIK-UHFFFAOYSA-N 0.000 description 1
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
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- 229960003415 propylparaben Drugs 0.000 description 1
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- 210000001147 pulmonary artery Anatomy 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
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- 235000017281 sodium acetate Nutrition 0.000 description 1
- 235000011083 sodium citrates Nutrition 0.000 description 1
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 description 1
- 239000000176 sodium gluconate Substances 0.000 description 1
- 235000012207 sodium gluconate Nutrition 0.000 description 1
- 229940005574 sodium gluconate Drugs 0.000 description 1
- 229910000104 sodium hydride Inorganic materials 0.000 description 1
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- 229940005581 sodium lactate Drugs 0.000 description 1
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- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
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- 235000012222 talc Nutrition 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4358608P | 2008-04-09 | 2008-04-09 | |
| PCT/US2009/040098 WO2009126822A2 (en) | 2008-04-09 | 2009-04-09 | Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010011050A true MX2010011050A (es) | 2010-11-01 |
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Family Applications (1)
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| MX2010011050A MX2010011050A (es) | 2008-04-09 | 2009-04-09 | Metodos para regular el reodernamiento citoesqueletico de actina y la formacion de aberturas intercelulares. |
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| Country | Link |
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| US (1) | US8809303B2 (https=) |
| EP (1) | EP2268286B1 (https=) |
| JP (1) | JP5562939B2 (https=) |
| KR (1) | KR20100135886A (https=) |
| CN (1) | CN102083443B (https=) |
| AU (1) | AU2009234156A1 (https=) |
| BR (1) | BRPI0911195A2 (https=) |
| CA (1) | CA2721082A1 (https=) |
| EA (1) | EA201001450A1 (https=) |
| ES (1) | ES2569608T3 (https=) |
| IL (1) | IL208565A0 (https=) |
| MX (1) | MX2010011050A (https=) |
| WO (1) | WO2009126822A2 (https=) |
| ZA (1) | ZA201007735B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0911195A2 (pt) | 2008-04-09 | 2017-06-20 | The Univ Of North Caroline At Chapel Hill | métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular |
| BRPI1010516A2 (pt) * | 2009-04-09 | 2015-08-25 | Univ North Carolina | Métodos de tratamento de edema relacionados à isquemia-reperfusão |
| CN103160570A (zh) * | 2011-12-09 | 2013-06-19 | 彩虹天健康科技研究(北京)有限责任公司 | Unc-51激酶和pp1磷酸酶相互作用机制的发现 |
| ES2985591T3 (es) * | 2018-02-12 | 2024-11-06 | Inimmune Corp | Ligandos de receptores tipo Toll |
| CN108836971B (zh) * | 2018-08-16 | 2020-10-30 | 青岛大学 | Ws6对小梁网细胞肌动蛋白形成的影响 |
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| US5628984A (en) | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
| US5843024A (en) | 1996-05-17 | 1998-12-01 | Breonics, Inc. | Solution and process for resuscitation and preparation of ischemically damaged tissue |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US6013640A (en) * | 1998-08-21 | 2000-01-11 | Ribi Immunochem Research, Inc. | Phosphoglycolipid and methods for its use |
| WO2001053462A1 (en) * | 2000-01-19 | 2001-07-26 | University Of North Carolina At Chapel Hill | Liver tissue source |
| US6699846B2 (en) * | 2000-03-17 | 2004-03-02 | Corixa Corporation | Mono- and disaccharides for the treatment of nitric oxide related disorders |
| WO2003105909A1 (ja) | 2002-06-13 | 2003-12-24 | 三菱ウェルファーマ株式会社 | 肝虚血再灌流傷害の予防及び／又は治療のための医薬並びに移植肝臓の保護剤 |
| US7960522B2 (en) | 2003-01-06 | 2011-06-14 | Corixa Corporation | Certain aminoalkyl glucosaminide phosphate compounds and their use |
| WO2005039504A2 (en) | 2003-10-24 | 2005-05-06 | Eisai Co., Ltd. | Compounds and methods for treating toll-like receptor 2-related diseases and conditions |
| US20060211752A1 (en) | 2004-03-16 | 2006-09-21 | Kohn Leonard D | Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression |
| US7928132B2 (en) | 2004-08-06 | 2011-04-19 | Ohio University | Methods for the amelioration of episodes of acute or chronic ulcerative colitis |
| WO2005117975A2 (en) | 2004-05-28 | 2005-12-15 | Cedars-Sinai Medical Center | Methods for treating vascular disease |
| ITMI20060530A1 (it) | 2006-03-22 | 2007-09-23 | Univ Milano Bicocca | Antinfiammatori a struttura monosaccaridica |
| US8734788B2 (en) | 2007-08-03 | 2014-05-27 | Opsona Therapeutics Ltd | Composition and method for treatment of reperfusion injury and tissue damage |
| BRPI0911195A2 (pt) | 2008-04-09 | 2017-06-20 | The Univ Of North Caroline At Chapel Hill | métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular |
| BRPI1010516A2 (pt) | 2009-04-09 | 2015-08-25 | Univ North Carolina | Métodos de tratamento de edema relacionados à isquemia-reperfusão |
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2009
- 2009-04-09 BR BRPI0911195A patent/BRPI0911195A2/pt not_active IP Right Cessation
- 2009-04-09 ES ES09730162.6T patent/ES2569608T3/es active Active
- 2009-04-09 JP JP2011504178A patent/JP5562939B2/ja not_active Expired - Fee Related
- 2009-04-09 WO PCT/US2009/040098 patent/WO2009126822A2/en not_active Ceased
- 2009-04-09 US US12/936,801 patent/US8809303B2/en not_active Expired - Fee Related
- 2009-04-09 EP EP09730162.6A patent/EP2268286B1/en active Active
- 2009-04-09 CA CA2721082A patent/CA2721082A1/en not_active Abandoned
- 2009-04-09 AU AU2009234156A patent/AU2009234156A1/en not_active Abandoned
- 2009-04-09 EA EA201001450A patent/EA201001450A1/ru unknown
- 2009-04-09 KR KR1020107024897A patent/KR20100135886A/ko not_active Withdrawn
- 2009-04-09 MX MX2010011050A patent/MX2010011050A/es active IP Right Grant
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2010
- 2010-10-07 IL IL208565A patent/IL208565A0/en unknown
- 2010-10-28 ZA ZA2010/07735A patent/ZA201007735B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2569608T3 (es) | 2016-05-11 |
| US20110053871A1 (en) | 2011-03-03 |
| IL208565A0 (en) | 2010-12-30 |
| EP2268286A1 (en) | 2011-01-05 |
| US8809303B2 (en) | 2014-08-19 |
| KR20100135886A (ko) | 2010-12-27 |
| ZA201007735B (en) | 2013-04-24 |
| CA2721082A1 (en) | 2009-10-15 |
| EP2268286A4 (en) | 2011-10-12 |
| CN102083443A (zh) | 2011-06-01 |
| WO2009126822A2 (en) | 2009-10-15 |
| CN102083443B (zh) | 2014-01-15 |
| EP2268286B1 (en) | 2016-04-06 |
| JP2011516572A (ja) | 2011-05-26 |
| BRPI0911195A2 (pt) | 2017-06-20 |
| AU2009234156A1 (en) | 2009-10-15 |
| EA201001450A1 (ru) | 2011-08-30 |
| WO2009126822A9 (en) | 2009-12-17 |
| JP5562939B2 (ja) | 2014-07-30 |
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